WormBase Tree Display for Gene: WBGene00001690
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| WBGene00001690 | Evidence | Paper_evidence | WBPaper00003717 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | R08B4 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | grd-1 | Person_evidence | WBPerson83 | |||||
| Sequence_name | R08B4.1 | ||||||||
| Molecular_name | R08B4.1 | ||||||||
| R08B4.1.1 | |||||||||
| CE34080 | |||||||||
| R08B4.1.2 | |||||||||
| Other_name | CELE_R08B4.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | grd-1 | ||||||||
| DB_info | Database | AceView | gene | XL733 | |||||
| WormQTL | gene | WBGene00001690 | |||||||
| WormFlux | gene | WBGene00001690 | |||||||
| NDB | locus_tag | CELE_R08B4.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001690|UniProtKB=Q7YXC8 | |||||||
| family | PTHR46706 | ||||||||
| NCBI | gene | 181300 | |||||||
| RefSeq | protein | NM_001029672.3 | |||||||
| TrEMBL | UniProtAcc | Q21835 | |||||||
| UniProt_GCRP | UniProtAcc | Q21835 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | grd | ||||||||
| Allele (93) | |||||||||
| Strain | WBStrain00035810 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (3) | |||||||||
| Ortholog (42) | |||||||||
| Paralog (24) | |||||||||
| Structured_description | Concise_description | grd-1 encodes a hedgehog-like protein, with (from N- to C-terminus) asignal sequence, a Ground domain, an extended region of low-complexitysequence, and a Hint/Hog domain; GRD-1 is expressed in rectal cells; theHint/Hog domain is predicted to cut GRD-1 into two halves and thencovalently link cholesterol to the C-terminus of the Ground domain; theGround domain is predicted to form a cysteine-crosslinked proteininvolved in intercellular signalling, and it has subtle similarity tothe N-terminal Hedge domain of HEDGEHOG proteins; GRD-1 is weaklyrequired for normal molting; GRD-1 is also required for normal growth tofull size, cuticle adhesion, and male tail development; all of theserequirements may reflect common defects in cholesterol-dependenthedgehog-like signalling or in vesicle trafficking. | Paper_evidence | WBPaper00003717 | |||||
| WBPaper00026841 | |||||||||
| WBPaper00027263 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 05 Nov 2006 00:00:00 | ||||||||
| Automated_description | Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in extracellular region. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | R08B4.1 | |||||||
| Corresponding_CDS_history | R08B4.1:wp52 | ||||||||
| R08B4.1:wp83 | |||||||||
| R08B4.1:wp101 | |||||||||
| R08B4.1b:wp272 | |||||||||
| Corresponding_transcript | R08B4.1.1 | ||||||||
| R08B4.1.2 | |||||||||
| Other_sequence (17) | |||||||||
| Associated_feature | WBsf648520 | ||||||||
| WBsf648521 | |||||||||
| WBsf1023814 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00076990 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00077015 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00051525 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00017576 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00111006 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr633 | ||||||||
| Expr4417 | |||||||||
| Expr1026738 | |||||||||
| Expr1031009 | |||||||||
| Expr1155201 | |||||||||
| Expr2012231 | |||||||||
| Expr2030467 | |||||||||
| Drives_construct | WBCnstr00011978 | ||||||||
| WBCnstr00012457 | |||||||||
| WBCnstr00036766 | |||||||||
| Construct_product | WBCnstr00036766 | ||||||||
| Microarray_results (27) | |||||||||
| Expression_cluster (197) | |||||||||
| Interaction | WBInteraction000114598 | ||||||||
| WBInteraction000114599 | |||||||||
| WBInteraction000114607 | |||||||||
| WBInteraction000173618 | |||||||||
| WBInteraction000237583 | |||||||||
| WBProcess | WBbiopr:00000123 | ||||||||
| Map_info | Map | X | Position | 2.85852 | Error | 0.000413 | |||
| Positive | Positive_clone | R08B4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4384 | |||||||
| 4421 | |||||||||
| 5511 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00002823 | ||||||||
| WBPaper00003717 | |||||||||
| WBPaper00011801 | |||||||||
| WBPaper00026841 | |||||||||
| WBPaper00027263 | |||||||||
| WBPaper00028754 | |||||||||
| WBPaper00031588 | |||||||||
| WBPaper00039178 | |||||||||
| WBPaper00062715 | |||||||||
| WBPaper00064105 | |||||||||
| WBPaper00066317 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
