WormBase Tree Display for Gene: WBGene00001579
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| WBGene00001579 | SMap | S_parent | Sequence | CHROMOSOME_IV | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | gex-2 | Person_evidence | WBPerson419 | |||||
| Sequence_name | F56A11.1 | ||||||||
| Molecular_name | F56A11.1 | ||||||||
| F56A11.1.1 | |||||||||
| CE31351 | |||||||||
| Other_name | CELE_F56A11.1 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | gex-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gex | ||||||||
| Allele (162) | |||||||||
| Strain | WBStrain00036391 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Ortholog (50) | |||||||||
| Structured_description | Concise_description | The gex-2 gene encodes a homolog of p140/Sra-1, a mammalian protein ligand of the small GTPase Rac1; gex-2 is required for tissue morphogenesis and cell migrations. | Paper_evidence | WBPaper00005149 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA 7-methylguanosine cap binding activity. Involved in several processes, including embryonic body morphogenesis; positive regulation of clathrin-dependent endocytosis; and positive regulation of egg-laying behavior. Located in cell junction. Part of SCAR complex. Human ortholog(s) of this gene implicated in several diseases, including Schaaf-Yang syndrome; autism spectrum disorder; and epilepsy (multiple). Is an ortholog of human CYFIP1 (cytoplasmic FMR1 interacting protein 1) and CYFIP2 (cytoplasmic FMR1 interacting protein 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111715 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13759) | ||||
| DOID:0080430 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13760) | ||||||
| DOID:0060041 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13759) | ||||||
| DOID:3328 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13759) | ||||||
| DOID:5419 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13759) | ||||||
| Molecular_info (5) | |||||||||
| Experimental_info | RNAi_result (33) | ||||||||
| Expr_pattern | Expr1827 | ||||||||
| Expr1026712 | |||||||||
| Expr1030945 | |||||||||
| Expr1152359 | |||||||||
| Expr2012023 | |||||||||
| Expr2030259 | |||||||||
| Drives_construct | WBCnstr00036849 | ||||||||
| Construct_product | WBCnstr00036849 | ||||||||
| Antibody | WBAntibody00000462 | ||||||||
| WBAntibody00000463 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (133) | |||||||||
| Interaction (42) | |||||||||
| Map_info | Map | IV | Position | -24.7527 | Error | 0.274792 | |||
| Positive | Positive_clone | F56A11 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5641 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005123 | ||||||||
| WBPaper00005194 | |||||||||
| WBPaper00005843 | |||||||||
| WBPaper00006422 | |||||||||
| WBPaper00010071 | |||||||||
| WBPaper00010423 | |||||||||
| WBPaper00010768 | |||||||||
| WBPaper00011871 | |||||||||
| WBPaper00013425 | |||||||||
| WBPaper00017095 | |||||||||
| WBPaper00018044 | |||||||||
| WBPaper00018124 | |||||||||
| WBPaper00018742 | |||||||||
| WBPaper00023294 | |||||||||
| WBPaper00026360 | |||||||||
| WBPaper00027244 | |||||||||
| WBPaper00027296 | |||||||||
| WBPaper00030644 | |||||||||
| WBPaper00032090 | |||||||||
| WBPaper00032282 | |||||||||
| WBPaper00032784 | |||||||||
| WBPaper00032907 | |||||||||
| WBPaper00033517 | |||||||||
| WBPaper00034889 | |||||||||
| WBPaper00034968 | |||||||||
| WBPaper00035252 | |||||||||
| WBPaper00036815 | |||||||||
| WBPaper00037146 | |||||||||
| WBPaper00037977 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00039213 | |||||||||
| WBPaper00039521 | |||||||||
| WBPaper00039779 | |||||||||
| WBPaper00048636 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061188 | |||||||||
| Remark | the 3' end is on C18H7 (nucleotides 1 to 3,000) | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
