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WormBase Tree Display for Gene: WBGene00000467

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Name Class

WBGene00000467SMapS_parentSequenceF52B5
IdentityVersion1
NameCGC_namecep-1Person_evidenceWBPerson539
Sequence_nameF52B5.5
Molecular_nameF52B5.5a
F52B5.5a.1
CE29805
F52B5.5b
CE38369
F52B5.5b.1
F52B5.5b.2
F52B5.5b.3
F52B5.5b.4
Other_nameCELE_F52B5.5Accession_evidenceNDBBX284601
Public_namecep-1
DB_infoDatabaseWormQTLgeneWBGene00000467
WormFluxgeneWBGene00000467
NDBlocus_tagCELE_F52B5.5
NCBIgene172616
RefSeqproteinNM_001026307.8
NM_001392668.1
SwissProtUniProtAccQ20646
UniProt_GCRPUniProtAccQ20646
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcep
Allele (54)
StrainWBStrain00022753
WBStrain00034662
WBStrain00034663
WBStrain00034811
WBStrain00035557
WBStrain00040683
WBStrain00004786
RNASeq_FPKM (74)
GO_annotation (45)
Ortholog (17)
Structured_descriptionConcise_descriptioncep-1 encodes an ortholog of the human tumor suppressor p53 (OMIM:191170, mutated in Li-Fraumeni syndrome) that promotes DNA damage-induced apoptosis and is required for normal meiotic segregation in the germ line, and affects sensitivity to hypoxia-induced lethality and longevity in response to starvation; CEP-1 is expressed ubiquitously in embryos and in the nucleoli of a subset of pharyngeal cells.Paper_evidenceWBPaper00004589
WBPaper00004919
WBPaper00004952
WBPaper00012759
WBPaper00012806
WBPaper00013586
WBPaper00013634
Curator_confirmedWBPerson48
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables several functions, including DNA-binding transcription factor activity; protein homodimerization activity; and zinc ion binding activity. Involved in several processes, including determination of adult lifespan; intracellular signal transduction; and positive regulation of transcription by RNA polymerase II. Located in germ cell nucleus; nucleolus; and nucleoplasm. Expressed in Z2; Z3; germ line; pharyngeal cell; and pharynx. Used to study cancer.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:162Homo sapiensPaper_evidenceWBPaper00004952
Curator_confirmedWBPerson324
Date_last_updated03 Feb 2020 00:00:00
Models_disease_in_annotationWBDOannot00000735
Molecular_info (7)
Experimental_info (11)
Map_infoMapIPosition2.73569Error0.00602
PositivePositive_cloneF52B5Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4212
4897
Pseudo_map_position
ReferenceWBPaper00004757
WBPaper00004919
WBPaper00004952
WBPaper00005597
WBPaper00005698
WBPaper00006339
WBPaper00010015
WBPaper00010377
WBPaper00013133
WBPaper00016598
WBPaper00016847
WBPaper00017077
WBPaper00017949
WBPaper00018146
WBPaper00018972
WBPaper00019399
WBPaper00019428
WBPaper00019492
WBPaper00023469
WBPaper00023993
WBPaper00024036
WBPaper00024051
WBPaper00024072
WBPaper00024290
WBPaper00024301
WBPaper00024354
WBPaper00024937
WBPaper00024954
WBPaper00025087
WBPaper00025091
WBPaper00025747
WBPaper00025933
WBPaper00025987
WBPaper00026229
WBPaper00026289
WBPaper00026339
WBPaper00026857
WBPaper00026934
WBPaper00027032
WBPaper00027172
WBPaper00027178
WBPaper00027215
WBPaper00027223
WBPaper00027421
WBPaper00027462
WBPaper00027594
WBPaper00027633
WBPaper00027648
WBPaper00027700
WBPaper00028397
WBPaper00028418
WBPaper00028420
WBPaper00028462
WBPaper00028477
WBPaper00028561
WBPaper00028759
WBPaper00028782
WBPaper00028948
WBPaper00029085
WBPaper00029132
WBPaper00029176
WBPaper00029200
WBPaper00030303
WBPaper00030412
WBPaper00030422
WBPaper00030775
WBPaper00030934
WBPaper00030994
WBPaper00031034
WBPaper00031056
WBPaper00031095
WBPaper00031253
WBPaper00031296
WBPaper00031318
WBPaper00031460
WBPaper00031557
WBPaper00031571
WBPaper00031605
WBPaper00031994
WBPaper00032022
WBPaper00032112
WBPaper00032132
WBPaper00032137
WBPaper00032220
WBPaper00032237
WBPaper00032243
WBPaper00032268
WBPaper00032356
WBPaper00032410
WBPaper00033066
WBPaper00033127
WBPaper00033129
WBPaper00033164
WBPaper00033279
WBPaper00033376
WBPaper00033433
WBPaper00033462
WBPaper00033761
WBPaper00033940
WBPaper00033961
WBPaper00033963
WBPaper00034305
WBPaper00034306
WBPaper00034523
WBPaper00034556
WBPaper00034799
WBPaper00034891
WBPaper00035215
WBPaper00035318
WBPaper00035505
WBPaper00035670
WBPaper00035946
WBPaper00035965
WBPaper00036108
WBPaper00036343
WBPaper00036429
WBPaper00036708
WBPaper00036748
WBPaper00036971
WBPaper00037696
WBPaper00037717
WBPaper00038001
WBPaper00038332
WBPaper00038703
WBPaper00038788
WBPaper00038927
WBPaper00039038
WBPaper00039044
WBPaper00039512
WBPaper00039522
WBPaper00039612
WBPaper00040167
WBPaper00040454
WBPaper00040627
WBPaper00040786
WBPaper00040806
WBPaper00041066
WBPaper00041146
WBPaper00041408
WBPaper00041495
WBPaper00041636
WBPaper00041756
WBPaper00041842
WBPaper00042351
WBPaper00042387
WBPaper00042800
WBPaper00043090
WBPaper00043113
WBPaper00043156
WBPaper00043639
WBPaper00043656
WBPaper00043659
WBPaper00043688
WBPaper00043757
WBPaper00043764
WBPaper00044006
WBPaper00044144
WBPaper00044530
WBPaper00044641
WBPaper00044798
WBPaper00044858
WBPaper00044938
WBPaper00044942
WBPaper00045135
WBPaper00045160
WBPaper00045374
WBPaper00045380
WBPaper00045529
WBPaper00045881
WBPaper00045919
WBPaper00046362
WBPaper00047291
WBPaper00047319
WBPaper00047796
WBPaper00047842
WBPaper00048895
WBPaper00048917
WBPaper00049178
WBPaper00049480
WBPaper00049555
WBPaper00050026
WBPaper00050185
WBPaper00050325
WBPaper00050602
WBPaper00051304
WBPaper00051429
WBPaper00051521
WBPaper00051565
WBPaper00052038
WBPaper00053133
WBPaper00053171
WBPaper00053317
WBPaper00054641
WBPaper00054936
WBPaper00054944
WBPaper00055127
WBPaper00055912
WBPaper00055968
WBPaper00056260
WBPaper00056435
WBPaper00056814
WBPaper00056888
WBPaper00057060
WBPaper00057093
WBPaper00057362
WBPaper00057391
WBPaper00057707
WBPaper00057788
WBPaper00058667
WBPaper00058851
WBPaper00059071
WBPaper00059531
WBPaper00059862
WBPaper00060598
WBPaper00060608
WBPaper00060623
WBPaper00060635
WBPaper00060693
WBPaper00061254
WBPaper00061470
WBPaper00061670
WBPaper00061938
WBPaper00062146
WBPaper00062454
WBPaper00062498
WBPaper00062559
WBPaper00062567
WBPaper00062587
WBPaper00062642
WBPaper00062645
WBPaper00062809
WBPaper00062826
WBPaper00062830
WBPaper00063038
WBPaper00063044
WBPaper00063123
WBPaper00063964
WBPaper00064084
WBPaper00064182
WBPaper00064212
WBPaper00064243
WBPaper00064255
WBPaper00064256
WBPaper00064312
WBPaper00064388
WBPaper00064609
WBPaper00065276
WBPaper00065765
WBPaper00065779
WBPaper00065862
WBPaper00065937
PictureWBPicture0000013091
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
[wm99ab616], [wm2001p535] and [jwm2000ab65] used cep-1 as an unapproved name for CGC plx-2 (K04B12.1). The CGC cep-1 (F52B5.5) is a p53 homolog.
MethodGene