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WormBase Tree Display for Gene: WBGene00000292

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Name Class

WBGene00000292SMapS_parentSequenceD2024
IdentityVersion1
NameCGC_namecap-1Person_evidenceWBPerson1562
Sequence_nameD2024.6
Molecular_nameD2024.6
D2024.6.1
CE04295
Other_nameCAPZ/A
CELE_D2024.6Accession_evidenceNDBBX284604
Public_namecap-1
DB_infoDatabaseAceViewgene4H994
WormQTLgeneWBGene00000292
WormFluxgeneWBGene00000292
NDBlocus_tagCELE_D2024.6
PanthergeneCAEEL|WormBase=WBGene00000292|UniProtKB=P34685
familyPTHR10653
NCBIgene177497
RefSeqproteinNM_068744.6
SwissProtUniProtAccP34685
TREEFAMTREEFAM_IDTF314822
UniProt_GCRPUniProtAccP34685
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcap
Allele (20)
Legacy_information[C.elegansII] NMK. Encodes homolog of actin capping protein, alpha subunit.Functional in yeast. [Waddle et al. 1993]
StrainWBStrain00028916
WBStrain00055410
RNASeq_FPKM (74)
GO_annotation (11)
Contained_in_operonCEOP4216
Ortholog (45)
Structured_descriptionConcise_descriptioncap-1 encodes an F-actin capping protein alpha subunit that affects fertility; likely expressed in touch receptor neurons.Paper_evidenceWBPaper00001839
WBPaper00004651
WBPaper00005356
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable actin filament binding activity. Predicted to be involved in actin cytoskeleton organization and barbed-end actin filament capping. Part of dynactin complex. Human ortholog(s) of this gene implicated in male infertility. Is an ortholog of human CAPZA1 (capping actin protein of muscle Z-line subunit alpha 1) and CAPZA2 (capping actin protein of muscle Z-line subunit alpha 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:12336Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:24205)
Molecular_infoCorresponding_CDSD2024.6
Corresponding_transcriptD2024.6.1
Other_sequence (48)
Associated_featureWBsf651895
WBsf668004
WBsf230233
WBsf230234
Experimental_infoRNAi_resultWBRNAi00088764Inferred_automaticallyRNAi_primary
WBRNAi00008578Inferred_automaticallyRNAi_primary
WBRNAi00090793Inferred_automaticallyRNAi_primary
WBRNAi00007972Inferred_automaticallyRNAi_primary
WBRNAi00043464Inferred_automaticallyRNAi_primary
WBRNAi00088657Inferred_automaticallyRNAi_primary
WBRNAi00091225Inferred_automaticallyRNAi_primary
WBRNAi00085703Inferred_automaticallyRNAi_primary
WBRNAi00091224Inferred_automaticallyRNAi_primary
WBRNAi00001944Inferred_automaticallyRNAi_primary
Expr_patternChronogram1048
Expr5625
Expr16434
Expr1010907
Expr1030189
Expr1147458
Expr2009715
Expr2027954
Drives_constructWBCnstr00002987
WBCnstr00009612
WBCnstr00037600
Construct_productWBCnstr00037600
AntibodyWBAntibody00001781
Microarray_results (20)
Expression_cluster (102)
Interaction (119)
Map_infoMapIVPosition3.30656Error0.001843
PositivePositive_clone (2)
Pseudo_map_position
ReferenceWBPaper00001839
WBPaper00002000
WBPaper00005356
WBPaper00014754
WBPaper00014852
WBPaper00015440
WBPaper00021014
WBPaper00022120
WBPaper00026225
WBPaper00037699
WBPaper00038491
WBPaper00047309
WBPaper00052206
WBPaper00055090
WBPaper00063091
WBPaper00065093
WBPaper00065275
WBPaper00065624
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene