ZK1236.5 encodes a protein with no obvious non-nematode homologs; eitherZK1236.9, or ZK1236.5, or both proteins weakly inhibit DHC-1 in vivo;likewise, either ZK1236.5, or ZK1236.9, or both proteins are required inmass RNAi assays for normal osmoregulation and normally rapid growth.
Enriched in NSM; germ line; and intestine based on RNA-seq and microarray studies. Is affected by several genes including hsf-1; let-7; and gld-1 based on proteomic; RNA-seq; and microarray studies. Is affected by seven chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies.