WormBase Tree Display for Gene: WBGene00012448
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| WBGene00012448 | SMap | S_parent | Sequence | CHROMOSOME_V | |||
|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||
| Name | CGC_name | cyp-33D3 | |||||
| Sequence_name | Y17D7A.4 | ||||||
| Molecular_name | Y17D7A.4 | ||||||
| Y17D7A.4.1 | |||||||
| CE16589 | |||||||
| Other_name | CELE_Y17D7A.4 | Accession_evidence | NDB | BX284605 | |||
| Public_name | cyp-33D3 | ||||||
| DB_info | Database | AceView | gene | 5T310 | |||
| WormQTL | gene | WBGene00012448 | |||||
| WormFlux | gene | WBGene00012448 | |||||
| NDB | locus_tag | CELE_Y17D7A.4 | |||||
| Panther | gene | CAEEL|WormBase=WBGene00012448|UniProtKB=G5EE22 | |||||
| family | PTHR24300 | ||||||
| NCBI | gene | 189444 | |||||
| RefSeq | protein | NM_075278.4 | |||||
| TrEMBL | UniProtAcc | G5EE22 | |||||
| UniProt_GCRP | UniProtAcc | G5EE22 | |||||
| OMIM | gene | 601130 | |||||
| 608713 | |||||||
| 610670 | |||||||
| Species | Caenorhabditis elegans | ||||||
| History | Version_change (2) | ||||||
| Status | Live | ||||||
| Gene_info | Biotype | SO:0001217 | |||||
| Gene_class | cyp | ||||||
| Allele (116) | |||||||
| RNASeq_FPKM (74) | |||||||
| GO_annotation (15) | |||||||
| Ortholog (114) | |||||||
| Paralog (44) | |||||||
| Structured_description | Automated_description | Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including Keshan disease; glucose metabolism disease (multiple); and hematologic cancer (multiple). Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2C19 (cytochrome P450 family 2 subfamily C member 19); and CYP2C8 (cytochrome P450 family 2 subfamily C member 8). | Paper_evidence | WBPaper00065943 | |||
| Curator_confirmed | WBPerson324 | ||||||
| WBPerson37462 | |||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
| Disease_info | Potential_model | DOID:3454 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||
| DOID:4195 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2623) | ||||
| DOID:1470 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||
| DOID:0080665 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2623) | ||||
| DOID:0050073 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||
| DOID:9744 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||
| DOID:13839 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||
| DOID:2559 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||
| DOID:0050741 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||
| DOID:2841 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||
| DOID:0050742 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2615) | ||||
| DOID:526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2615) | ||||
| DOID:9538 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621,HGNC:2625) | ||||
| DOID:9351 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2623) | ||||
| DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2623) | ||||
| DOID:10923 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||
| DOID:5844 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||
| DOID:4248 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||
| DOID:1073 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2622) | ||||
| DOID:0110808 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20582) | ||||
| DOID:9974 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2615) | ||||
| DOID:9993 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2623) | ||||
| DOID:14067 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||
| DOID:11714 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||
| DOID:10591 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||
| DOID:10763 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580,HGNC:2623) | ||||
| DOID:9952 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||
| DOID:750 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||
| DOID:2048 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||
| DOID:9976 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2615) | ||||
| DOID:9828 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2615) | ||||
| DOID:9970 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||
| DOID:399 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2615,HGNC:2621) | ||||
| DOID:0050083 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||
| DOID:11054 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2623) | ||||
| DOID:13922 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||
| DOID:4483 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||
| DOID:783 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2622) | ||||
| DOID:12930 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||
| DOID:4661 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||
| DOID:3393 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||
| DOID:5520 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621,HGNC:2623,HGNC:2625) | ||||
| DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||
| DOID:0080887 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||
| DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||
| DOID:9119 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2615,HGNC:2625) | ||||
| Molecular_info | Corresponding_CDS | Y17D7A.4 | |||||
| Corresponding_CDS_history | Y17D7A.4:wp106 | ||||||
| Corresponding_transcript | Y17D7A.4.1 | ||||||
| Other_sequence (20) | |||||||
| Associated_feature | WBsf982076 | ||||||
| WBsf1003019 | |||||||
| WBsf1021557 | |||||||
| Experimental_info | RNAi_result | WBRNAi00036657 | Inferred_automatically | RNAi_primary | |||
| WBRNAi00092667 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00055560 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00095077 | Inferred_automatically | RNAi_primary | |||||
| Expr_pattern | Expr1021931 | ||||||
| Expr1159061 | |||||||
| Expr2010722 | |||||||
| Expr2028960 | |||||||
| Microarray_results (15) | |||||||
| Expression_cluster (106) | |||||||
| Interaction (35) | |||||||
| Map_info | Map | V | Position | 18.0657 | Error | 0.02692 | |
| Positive | Positive_clone | Y17D7A | Inferred_automatically | From sequence, transcript, pseudogene data | |||
| Pseudo_map_position | |||||||
| Reference | WBPaper00038491 | ||||||
| WBPaper00055090 | |||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
| Method | Gene |
