WormBase Tree Display for Gene: WBGene00012448
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WBGene00012448 | SMap | S_parent | Sequence | CHROMOSOME_V | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | cyp-33D3 | |||||||
Sequence_name | Y17D7A.4 | ||||||||
Molecular_name | Y17D7A.4 | ||||||||
Y17D7A.4.1 | |||||||||
CE16589 | |||||||||
Other_name | CELE_Y17D7A.4 | Accession_evidence | NDB | BX284605 | |||||
Public_name | cyp-33D3 | ||||||||
DB_info | Database | AceView | gene | 5T310 | |||||
WormQTL | gene | WBGene00012448 | |||||||
WormFlux | gene | WBGene00012448 | |||||||
NDB | locus_tag | CELE_Y17D7A.4 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00012448|UniProtKB=G5EE22 | |||||||
family | PTHR24300 | ||||||||
NCBI | gene | 189444 | |||||||
RefSeq | protein | NM_075278.4 | |||||||
TrEMBL | UniProtAcc | G5EE22 | |||||||
UniProt_GCRP | UniProtAcc | G5EE22 | |||||||
OMIM | gene | 601130 | |||||||
608713 | |||||||||
610670 | |||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:53 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 21 Sep 2004 09:38:16 | WBPerson1971 | Name_change | CGC_name | cyp-33D3 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | cyp | ||||||||
Allele (116) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (15) | |||||||||
Ortholog (114) | |||||||||
Paralog (44) | |||||||||
Structured_description | Automated_description | Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including Keshan disease; glucose metabolism disease (multiple); and hematologic cancer (multiple). Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2C19 (cytochrome P450 family 2 subfamily C member 19); and CYP2C8 (cytochrome P450 family 2 subfamily C member 8). | Paper_evidence | WBPaper00065943 | |||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:3454 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||
DOID:4195 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2623) | ||||||
DOID:1470 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||||
DOID:0080665 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2623) | ||||||
DOID:0050073 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||||
DOID:9744 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||||
DOID:13839 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||||
DOID:2559 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||||
DOID:0050741 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||||
DOID:2841 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||||
DOID:0050742 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2615) | ||||||
DOID:526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2615) | ||||||
DOID:9538 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621,HGNC:2625) | ||||||
DOID:9351 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2623) | ||||||
DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2623) | ||||||
DOID:10923 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||||
DOID:5844 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||||
DOID:4248 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||||
DOID:1073 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2622) | ||||||
DOID:0110808 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20582) | ||||||
DOID:9974 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2615) | ||||||
DOID:9993 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2623) | ||||||
DOID:14067 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||||
DOID:11714 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||||
DOID:10591 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||||
DOID:10763 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580,HGNC:2623) | ||||||
DOID:9952 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||||
DOID:750 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||||
DOID:2048 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||||
DOID:9976 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2615) | ||||||
DOID:9828 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2615) | ||||||
DOID:9970 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||||
DOID:399 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2615,HGNC:2621) | ||||||
DOID:0050083 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||||
DOID:11054 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2623) | ||||||
DOID:13922 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||||
DOID:4483 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2625) | ||||||
DOID:783 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2622) | ||||||
DOID:12930 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||||
DOID:4661 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||||
DOID:3393 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||||
DOID:5520 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621,HGNC:2623,HGNC:2625) | ||||||
DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||||
DOID:0080887 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20580) | ||||||
DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2621) | ||||||
DOID:9119 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2615,HGNC:2625) | ||||||
Molecular_info | Corresponding_CDS | Y17D7A.4 | |||||||
Corresponding_CDS_history | Y17D7A.4:wp106 | ||||||||
Corresponding_transcript | Y17D7A.4.1 | ||||||||
Other_sequence (20) | |||||||||
Associated_feature (3) | |||||||||
Experimental_info | RNAi_result | WBRNAi00036657 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00092667 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00055560 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00095077 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr1021931 | ||||||||
Expr1159061 | |||||||||
Expr2010722 | |||||||||
Expr2028960 | |||||||||
Microarray_results (15) | |||||||||
Expression_cluster (106) | |||||||||
Interaction (35) | |||||||||
Map_info | Map | V | Position | 18.0657 | Error | 0.02692 | |||
Positive | Positive_clone | Y17D7A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00038491 | ||||||||
WBPaper00055090 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |