WormBase Tree Display for Gene: WBGene00020788
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| WBGene00020788 | SMap | S_parent | Sequence | T25B6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | nep-22 | Person_evidence | WBPerson260 | |||||
| Sequence_name | T25B6.2 | ||||||||
| Molecular_name | T25B6.2 | ||||||||
| T25B6.2.1 | |||||||||
| CE14174 | |||||||||
| Other_name | CELE_T25B6.2 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | nep-22 | ||||||||
| DB_info | Database | AceView | gene | XJ655 | |||||
| WormQTL | gene | WBGene00020788 | |||||||
| WormFlux | gene | WBGene00020788 | |||||||
| NDB | locus_tag | CELE_T25B6.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00020788|UniProtKB=Q22763 | |||||||
| family | PTHR11733 | ||||||||
| NCBI | gene | 181144 | |||||||
| RefSeq | protein | NM_077127.5 | |||||||
| TREEFAM | TREEFAM_ID | TF318791 | |||||||
| TrEMBL | UniProtAcc | Q22763 | |||||||
| UniProt_GCRP | UniProtAcc | Q22763 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:03 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 10 Feb 2012 15:49:10 | WBPerson2970 | Name_change | CGC_name | nep-22 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nep | ||||||||
| Allele (69) | |||||||||
| Strain | WBStrain00033138 | ||||||||
| WBStrain00037406 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Ortholog (31) | |||||||||
| Paralog (24) | |||||||||
| Structured_description | Concise_description | nep-22 encodes two isoforms of a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; NEP-22 is orthologous to Ac-mep-1, a gut luminal neprilysin which is specifically expressed in the adult life stage of Ancylostoma caninum hookworms, and whose protein product is localized to the microvilli of the gastrointestinal tract, suggesting a role in digestion. | Paper_evidence (3) | ||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 27 Mar 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Located in membrane raft. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T25B6.2 | |||||||
| Corresponding_CDS_history | T25B6.2a:wp142 | ||||||||
| T25B6.2b:wp142 | |||||||||
| Corresponding_transcript | T25B6.2.1 | ||||||||
| Other_sequence | BG467946.1 | ||||||||
| Oden_isotig08553 | |||||||||
| EX554801.1 | |||||||||
| FC548711.1 | |||||||||
| PP01162 | |||||||||
| Acan_isotig04100 | |||||||||
| Name_isotig05623 | |||||||||
| AM744499.1 | |||||||||
| Tcol_isotig11890 | |||||||||
| SRC03078_1 | |||||||||
| AY371702.1 | |||||||||
| NAC00619_1 | |||||||||
| EX553566.1 | |||||||||
| FC542709.1 | |||||||||
| Oden_isotig08552 | |||||||||
| Dviv_isotig05919 | |||||||||
| TDC02656_1 | |||||||||
| Oden_isotig08555 | |||||||||
| Tcol_isotig11756 | |||||||||
| TDC02591_1 | |||||||||
| Acan_isotig02780 | |||||||||
| GR979011.1 | |||||||||
| CR11966 | |||||||||
| CBC00857_1 | |||||||||
| HC00041 | |||||||||
| CR00957 | |||||||||
| Dviv_isotig05917 | |||||||||
| Tcol_isotig11757 | |||||||||
| AM744675.1 | |||||||||
| HC02353 | |||||||||
| EX559525.1 | |||||||||
| FC554366.1 | |||||||||
| Oden_isotig08556 | |||||||||
| Acan_isotig04101 | |||||||||
| PPC10309_1 | |||||||||
| HC00029 | |||||||||
| AM744216.1 | |||||||||
| FC548399.1 | |||||||||
| ACC10489_1 | |||||||||
| Oden_isotig19419 | |||||||||
| AE01834 | |||||||||
| Tcir_isotig10241 | |||||||||
| AM743989.1 | |||||||||
| Acan_isotig02779 | |||||||||
| EU523699.1 | |||||||||
| Tcol_isotig09410 | |||||||||
| ACC21319_1 | |||||||||
| Oden_isotig08557 | |||||||||
| PPC00038_1 | |||||||||
| SR02579 | |||||||||
| TDC03008_1 | |||||||||
| Acan_isotig11427 | |||||||||
| HCC00065_1 | |||||||||
| HCC09838_2 | |||||||||
| EX536157.1 | |||||||||
| ACC20049_1 | |||||||||
| Tcol_isotig07696 | |||||||||
| Name_isotig04355 | |||||||||
| BG468114.1 | |||||||||
| HC02423 | |||||||||
| AM744278.1 | |||||||||
| EX555628.1 | |||||||||
| HC02444 | |||||||||
| HCC00092_1 | |||||||||
| HC02443 | |||||||||
| Name_isotig01564 | |||||||||
| Tcir_isotig07739 | |||||||||
| CRC02087_1 | |||||||||
| EX567169.1 | |||||||||
| CJC03696_1 | |||||||||
| FC548285.1 | |||||||||
| HCC09809_1 | |||||||||
| Dviv_isotig05918 | |||||||||
| AF273084.3 | |||||||||
| PPC02835_1 | |||||||||
| ACC15125_1 | |||||||||
| Name_isotig03157 | |||||||||
| EY464891.1 | |||||||||
| SC01262 | |||||||||
| AYC00067_1 | |||||||||
| HC02468 | |||||||||
| EX539316.1 | |||||||||
| HCC09838_1 | |||||||||
| JI170392.1 | |||||||||
| FC815811.1 | |||||||||
| Tcir_isotig19159 | |||||||||
| HC02312 | |||||||||
| Tcir_isotig14237 | |||||||||
| Tcol_isotig07697 | |||||||||
| Tcol_isotig11891 | |||||||||
| Tcol_isotig09411 | |||||||||
| EX540448.1 | |||||||||
| PP01996 | |||||||||
| HC05907 | |||||||||
| Oden_isotig22935 | |||||||||
| AF273706.1 | |||||||||
| FC810408.1 | |||||||||
| AE01712 | |||||||||
| Oden_isotig08554 | |||||||||
| AY371701.1 | |||||||||
| FC555308.1 | |||||||||
| HCC11346_1 | |||||||||
| Associated_feature | WBsf648394 | ||||||||
| WBsf236116 | |||||||||
| WBsf236117 | |||||||||
| WBsf236118 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00054097 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00000575 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00035945 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00089168 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00019187 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1019959 | ||||||||
| Expr1039054 | |||||||||
| Expr1157641 | |||||||||
| Expr2013967 | |||||||||
| Expr2032206 | |||||||||
| Drives_construct | WBCnstr00024887 | ||||||||
| Construct_product | WBCnstr00024887 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (260) | |||||||||
| Interaction (40) | |||||||||
| Map_info | Map | X | Position | 0.573562 | |||||
| Positive | Positive_clone | T25B6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00011415 | ||||||||
| WBPaper00011735 | |||||||||
| WBPaper00029046 | |||||||||
| WBPaper00037777 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
