WormBase Tree Display for Gene: WBGene00013866
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| WBGene00013866 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cbs-1 | Paper_evidence | WBPaper00039977 | |||||
| Person_evidence | WBPerson537 | ||||||||
| Sequence_name | ZC373.1 | ||||||||
| Molecular_name | ZC373.1a | ||||||||
| ZC373.1a.1 | |||||||||
| CE31670 | |||||||||
| ZC373.1b | |||||||||
| CE47092 | |||||||||
| ZC373.1b.1 | |||||||||
| Other_name | CELE_ZC373.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | cbs-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 29 Sep 2011 10:45:56 | WBPerson2970 | Name_change | CGC_name | cbs-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cbs | ||||||||
| Allele (32) | |||||||||
| Strain | WBStrain00002826 | ||||||||
| WBStrain00052082 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (40) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | cbs-1 encodes an ortholog of human CYSTATHIONINE-BETA-SYNTHASE (CBS), which when mutated leads to homocystinuria (OMIM:236200). | Paper_evidence | WBPaper00004637 | |||||
| Curator_confirmed (2) | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables cystathionine beta-synthase activity; cysteine synthase activity; and pyridoxal phosphate binding activity. Involved in sulfur compound biosynthetic process. Located in cytoplasm. Expressed in pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including homocystinuria; hyperhomocysteinemia; and neural tube defect. Is an ortholog of human CBS (cystathionine beta-synthase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed (2) | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0080074 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||
| DOID:12365 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
| DOID:9279 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
| DOID:9263 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
| DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
| DOID:3393 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
| Molecular_info | Corresponding_CDS | ZC373.1a | |||||||
| ZC373.1b | |||||||||
| Corresponding_CDS_history | ZC373.1:wp83 | ||||||||
| Corresponding_transcript | ZC373.1a.1 | ||||||||
| ZC373.1b.1 | |||||||||
| Other_sequence | FK801091.1 | ||||||||
| Dviv_isotig23720 | |||||||||
| FC550040.1 | |||||||||
| Tcol_isotig09234 | |||||||||
| DA00566 | |||||||||
| ASC04571_1 | |||||||||
| Name_isotig04502 | |||||||||
| Oden_contig17017 | |||||||||
| CR05880 | |||||||||
| FC544001.1 | |||||||||
| EY468679.1 | |||||||||
| EY458745.1 | |||||||||
| Acan_isotig07712 | |||||||||
| DAC02391_1 | |||||||||
| Oden_contig17014 | |||||||||
| PPC21242_1 | |||||||||
| MCC02823_1 | |||||||||
| Tcol_isotig08704 | |||||||||
| CJC04585_1 | |||||||||
| CBC08801_1 | |||||||||
| CR05722 | |||||||||
| Tcir_isotig17073 | |||||||||
| AS00878 | |||||||||
| CR04750 | |||||||||
| MC03041 | |||||||||
| ASC20683_1 | |||||||||
| FC547441.1 | |||||||||
| ACC00791_1 | |||||||||
| HBC09889_1 | |||||||||
| Hbac_isotig01501 | |||||||||
| EX565880.1 | |||||||||
| EX556439.1 | |||||||||
| AS06987 | |||||||||
| JI168178.1 | |||||||||
| Oden_isotig08939 | |||||||||
| EX912129.1 | |||||||||
| Tcol_isotig09235 | |||||||||
| PT00570 | |||||||||
| EX555751.1 | |||||||||
| CRC00907_1 | |||||||||
| Associated_feature | WBsf648441 | ||||||||
| WBsf655205 | |||||||||
| WBsf1006596 | |||||||||
| WBsf236234 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00058845 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00091457 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1051 | ||||||||
| Expr7160 | |||||||||
| Expr9921 | |||||||||
| Expr1018878 | |||||||||
| Expr1036202 | |||||||||
| Expr1162289 | |||||||||
| Expr2009744 | |||||||||
| Expr2027984 | |||||||||
| Drives_construct | WBCnstr00003351 | ||||||||
| WBCnstr00014401 | |||||||||
| WBCnstr00029491 | |||||||||
| Construct_product | WBCnstr00014401 | ||||||||
| WBCnstr00016327 | |||||||||
| WBCnstr00029491 | |||||||||
| Antibody | WBAntibody00002306 | ||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (173) | |||||||||
| Interaction (63) | |||||||||
| Map_info | Map | X | Position | 1.73547 | |||||
| Positive | Positive_clone | ZC373 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00034443 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00040475 | |||||||||
| WBPaper00040626 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059856 | |||||||||
| WBPaper00059949 | |||||||||
| WBPaper00060431 | |||||||||
| WBPaper00060693 | |||||||||
| WBPaper00064989 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
