T13H5.8 is the closest C. elegans homolog of the human gene CRR9, which promotes cisplatin-induced apoptosis in ovarian cancer cells, and of CLPTM1, a human gene associated with cleft lip and palate.
Predicted to be located in endomembrane system and membrane. Human ortholog(s) of this gene implicated in carcinoma (multiple) and pulmonary emphysema. Is an ortholog of human CLPTM1L (CLPTM1 like).