WormBase Tree Display for Gene: WBGene00002064

WBGene00002064 SMap: S_parent: Sequence: T05G5
  Identity: Version: 1
    Name: CGC_name: iff-1 Person_evidence: WBPerson284
      Sequence_name: T05G5.10
      Molecular_name: T05G5.10a
        T05G5.10a.1
        CE37787
        T05G5.10b
        CE00503
        T05G5.10c
        CE46328
        T05G5.10b.1
        T05G5.10c.1
      Other_name: CELE_T05G5.10 Accession_evidence: NDB BX284603
      Public_name: iff-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:26 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: iff
    Allele (19)
    Strain: WBStrain00022686
      WBStrain00022688
    RNASeq_FPKM (74)
    GO_annotation (24)
    Ortholog (38)
    Paralog: WBGene00002065 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: iff-1 encodes an eIF-5A homolog that affects fertility and is required for germ cell proliferation and for some P granule components to localize properly; expression is germline specific and mRNA is expressed in the distal region of gonads where germ cells actively proliferate. Paper_evidence: WBPaper00012310
            WBPaper00018717
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable translation elongation factor activity. Involved in gamete generation and protein localization. Predicted to be located in cytoplasm. Expressed in germ line and gonad. Human ortholog(s) of this gene implicated in colorectal cancer. Is an ortholog of human EIF5A (eukaryotic translation initiation factor 5A). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9256 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3300)
  Molecular_info: Corresponding_CDS: T05G5.10a
      T05G5.10b
      T05G5.10c
    Corresponding_CDS_history: T05G5.10:wp135
    Corresponding_transcript: T05G5.10a.1
      T05G5.10b.1
      T05G5.10c.1
    Other_sequence: CBC07974_1
      EX912571.1
      MP00087
      OF01523
      PTC00482_1
      Dviv_isotig08946
      ES744331.1
      EX013622.1
      FF681478.1
      ES740863.1
      ACC24581_1
      EX914020.1
      ES744570.1
      EX012196.1
      EX011195.1
      AE01049
      ES411253.1
      EX911598.1
      PPC03791_1
      HC03776
      EX012973.1
      ES410218.1
      EG025646.1
      BMC01550_1
      EX914314.1
      HBC02102_1
      FC541039.1
      CR10487
      CJC08836_1
      AE01701
      PVC00537_1
      ES411976.1
      EX915024.1
      NBC00600_1
      ES740253.1
      CJC00838_1
      EL888030.1
      EX912965.1
      EX014285.1
      ES409915.1
      EX915710.1
      MCC02179_1
      Acan_isotig09401
      EX558521.1
      ES741498.1
      EX914584.1
      CRC02893_1
      PP00581
      ES411155.1
      EX911550.1
      ES411371.1
      EX911782.1
      ES413863.1
      EX013675.1
      EX915236.1
      AYC00377_1
      ES410009.1
      EX914822.1
      OOC03231_1
      MC01112
      Dviv_isotig08948
      EX014475.1
      CJC08533_1
      ES744296.1
      ES411075.1
      ES411945.1
      Name_isotig00697
      EX008194.1
      EX913448.1
      NB07514
      ES743074.1
      EX010310.1
      EX011356.1
      ES743703.1
      EX916649.1
      PT01146
      ES740244.1
      HCC12894_1
      ES409715.1
      HBC15067_1
      AE00720
      Hbac_isotig03681
      BXC06834_1
      HBC25534_1
      ES743296.1
      NB07698
      Oden_isotig17807
      EX561491.1
      EX910129.1
      PPC00071_1
      EX015085.1
      ES412912.1
      ES741663.1
      EX911461.1
      EX012360.1
      ACC01188_1
      HC02328
      EX916450.1
      EX915188.1
      FF680529.1
      EX008361.1
      Dviv_isotig08947
      CBC02723_1
      EX009056.1
      CR02282
      EX916280.1
      MPC00853_1
    Associated_feature: WBsf651400
      WBsf667319
      WBsf667320
      WBsf993786
      WBsf1015666
  Experimental_info: RNAi_result (15)
    Expr_pattern: Expr2909
      Expr2911
      Expr2912
      Expr1021225
      Expr1031217
      Expr1156177
      Expr2012691
      Expr2030927
    Drives_construct: WBCnstr00036483
    Construct_product: WBCnstr00036483
    Regulate_expr_cluster: WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_upregulated_protein
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
    Antibody: WBAntibody00000726
    Microarray_results (23)
    Expression_cluster (235)
    Interaction (346)
  Map_info: Map: III Position: 0.949142 Error: 0.006732
    Positive: Positive_clone: T05G5 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4195
        4435
    Pseudo_map_position
  Reference (15)
  Remark (2)
  Method: Gene