WormBase Tree Display for Gene: WBGene00000991
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WBGene00000991 | SMap | S_parent | Sequence | M03A8 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | dhs-28 | Person_evidence | WBPerson651 | |||||
Sequence_name | M03A8.1 | ||||||||
Molecular_name | M03A8.1 | ||||||||
M03A8.1.1 | |||||||||
CE04770 | |||||||||
Other_name | CELE_M03A8.1 | Accession_evidence | NDB | BX284606 | |||||
Public_name | dhs-28 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | dhs | ||||||||
Allele (44) | |||||||||
Strain | WBStrain00035626 | ||||||||
WBStrain00040189 | |||||||||
WBStrain00050737 | |||||||||
WBStrain00050738 | |||||||||
WBStrain00050736 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (16) | |||||||||
Ortholog (37) | |||||||||
Paralog (38) | |||||||||
Structured_description | Concise_description | dhs-28 encodes an ortholog of human 17-BETA-HYDROXYSTEROID DEHYDROGENASE 4 (HSD17B4; OMIM:601860, mutated in D-bifunctional protein deficiency), which contains a C-terminal SCP-2 sterol transfer domain; the deletion allele dhs-28(ok450) is superficially wild-type. | Paper_evidence | WBPaper00004424 | |||||
Curator_confirmed | WBPerson48 | ||||||||
WBPerson1823 | |||||||||
WBPerson567 | |||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable oxidoreductase activity. Involved in several processes, including carbohydrate derivative metabolic process; dauer entry; and positive regulation of developmental process. Located in peroxisome. Expressed in hypodermis. Used to study obesity. Human ortholog(s) of this gene implicated in D-bifunctional protein deficiency; Perrault syndrome; and Stiff-Person syndrome. Is an ortholog of human HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Experimental_model | DOID:9970 | Homo sapiens | Paper_evidence | WBPaper00035972 | ||||
Curator_confirmed | WBPerson38202 | ||||||||
Date_last_updated | 29 Jun 2018 00:00:00 | ||||||||
Potential_model | DOID:13366 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5213) | |||||
DOID:0090031 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5213) | ||||||
DOID:0050857 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5213) | ||||||
Models_disease_asserted | WBDOannot00000570 | ||||||||
WBDOannot00000571 | |||||||||
Molecular_info | Corresponding_CDS | M03A8.1 | |||||||
Corresponding_transcript | M03A8.1.1 | ||||||||
Other_sequence | ES409494.1 | ||||||||
Tcol_isotig15320 | |||||||||
JI175696.1 | |||||||||
ES742001.1 | |||||||||
ES740579.1 | |||||||||
EX008020.1 | |||||||||
ES743105.1 | |||||||||
HBC00713_1 | |||||||||
EX007995.1 | |||||||||
EX913254.1 | |||||||||
CJC00939_1 | |||||||||
HBC02656_1 | |||||||||
ES742784.1 | |||||||||
NB08368 | |||||||||
ES409605.1 | |||||||||
EX915940.1 | |||||||||
PTC02309_1 | |||||||||
MIC07264_1 | |||||||||
EX912978.1 | |||||||||
EL890835.1 | |||||||||
FK800478.1 | |||||||||
Acan_isotig03045 | |||||||||
DA03914 | |||||||||
FK803675.1 | |||||||||
EX911739.1 | |||||||||
CBC08636_1 | |||||||||
FK801001.1 | |||||||||
EX009336.1 | |||||||||
EX915699.1 | |||||||||
EX913496.1 | |||||||||
Name_isotig04470 | |||||||||
ES742501.1 | |||||||||
MI02213 | |||||||||
EX013769.1 | |||||||||
AS16466 | |||||||||
ES413868.1 | |||||||||
BMC00580_1 | |||||||||
ES413909.1 | |||||||||
BXC01052_1 | |||||||||
FG976518.1 | |||||||||
HBC10088_1 | |||||||||
HG11581 | |||||||||
JO469098.1 | |||||||||
EX009360.1 | |||||||||
FG974936.1 | |||||||||
Acan_isotig03043 | |||||||||
Tcir_isotig01124 | |||||||||
PPC19939_1 | |||||||||
ES743369.1 | |||||||||
HBC05012_1 | |||||||||
AE03019 | |||||||||
EX010573.1 | |||||||||
ASC04785_1 | |||||||||
ES741956.1 | |||||||||
EX014067.1 | |||||||||
ES409557.1 | |||||||||
EX564706.1 | |||||||||
AS03099 | |||||||||
JI215521.1 | |||||||||
BXC07421_1 | |||||||||
ES739011.1 | |||||||||
EX566539.1 | |||||||||
EX008183.1 | |||||||||
ES413847.1 | |||||||||
BXC03301_1 | |||||||||
Tcir_isotig32643 | |||||||||
FG980499.1 | |||||||||
HGC00713_1 | |||||||||
HG05888 | |||||||||
FK807586.1 | |||||||||
ES413154.1 | |||||||||
FK805046.1 | |||||||||
FK805785.1 | |||||||||
ES409088.1 | |||||||||
EX914627.1 | |||||||||
EX913751.1 | |||||||||
FK802655.1 | |||||||||
EX915395.1 | |||||||||
ES413900.1 | |||||||||
BUC00010_1 | |||||||||
Oden_isotig10755 | |||||||||
ASC19587_1 | |||||||||
ES413375.1 | |||||||||
CJC02986_1 | |||||||||
AYC01478_1 | |||||||||
AE00571 | |||||||||
SS01307 | |||||||||
Acan_isotig03044 | |||||||||
ES409371.1 | |||||||||
Tcir_isotig01126 | |||||||||
DAC01670_1 | |||||||||
ES413644.1 | |||||||||
PVC02572_1 | |||||||||
ACC09981_1 | |||||||||
EX014751.1 | |||||||||
Name_isotig06051 | |||||||||
AYC02412_1 | |||||||||
BU493347.1 | |||||||||
Tcir_isotig01125 | |||||||||
Dviv_isotig23657 | |||||||||
Tcir_isotig01127 | |||||||||
NBC00696 | |||||||||
HBC02227_1 | |||||||||
Hbac_isotig01510 | |||||||||
EX010250.1 | |||||||||
EX009344.1 | |||||||||
SSC02944_1 | |||||||||
Associated_feature | WBsf648263 | ||||||||
WBsf648264 | |||||||||
WBsf662918 | |||||||||
WBsf235872 | |||||||||
WBsf235873 | |||||||||
Experimental_info | RNAi_result | WBRNAi00108444 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00008998 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00050847 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00034393 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00025981 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00092604 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr8991 | ||||||||
Expr1020554 | |||||||||
Expr1030616 | |||||||||
Expr1154542 | |||||||||
Expr2010912 | |||||||||
Expr2029151 | |||||||||
Drives_construct | WBCnstr00013659 | ||||||||
WBCnstr00037154 | |||||||||
Construct_product (3) | |||||||||
Antibody | WBAntibody00001955 | ||||||||
WBAntibody00002918 | |||||||||
Microarray_results (27) | |||||||||
Expression_cluster (216) | |||||||||
Interaction (99) | |||||||||
Map_info | Map | X | Position | -2.40245 | Error | 0.010942 | |||
Positive | Positive_clone | M03A8 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4258 | |||||||
4343 | |||||||||
5031 | |||||||||
Pseudo_map_position | |||||||||
Reference (31) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |