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WormBase Tree Display for Gene: WBGene00000786

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Name Class

WBGene00000786SMapS_parentSequenceC25B8
IdentityVersion1
Name (5)
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcpr
Allele (38)
Legacy_information[C.elegansII] pk91 : Tc1 insertion, no known phenotype. Encodes protein with significant similarity to proteases of Cathepsin B family (EST cm01a5). [IA]
RNASeq_FPKM (74)
GO_annotation00046005
00046006
00046007
00046008
00046009
00046010
00046011
00046012
00107792
00107793
Ortholog (35)
Paralog (28)
Structured_descriptionAutomated_descriptionPredicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Located in lysosome. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9351Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:11054Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:2671Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:9352Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:2377Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:10941Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:12842Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:3068Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:4914Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:1612Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
Molecular_infoCorresponding_CDSC25B8.3
Corresponding_CDS_historyC25B8.3b:wp271
C25B8.3c:wp271
Corresponding_transcriptC25B8.3.1
Other_sequenceFF678747.1
FG974435.1
Oden_isotig04117
Oden_isotig04122
CB037526.1
HSC00167_1
FK809614.1
FF678381.1
FG975588.1
ES742675.1
FK803173.1
EL889031.1
HCC10778_1
FK809130.1
AJ296150.1
Tcol_isotig23130
ACC39653_1
EX543216.1
FK809276.1
EV853262.1
ES672312.1
HC01934
FG972897.1
FC817594.1
Oden_isotig04127
EX546058.1
EV853216.1
Tcir_isotig27644
ES672359.1
HCC01418_1
BG354832.1
EX542186.1
FK802386.1
EX562049.1
FK803273.1
FG979874.1
FD513939.1
Oden_isotig04111
FK804962.1
FG974270.1
JO472732.1
Dviv_isotig03268
Hbac_isotig07545
FC815016.1
DVC00434_1
HC01681
NBC00030_1
Oden_isotig20299
FG981124.1
FG975238.1
FK806713.1
HC00008
EX540773.1
CBC15304_1
GO252887.1
BG468103.1
EX558881.1
EX500682.1
HCC05928_1
HCC02966_3
FE916861.1
HC02450
EX012656.1
FK809691.1
FK806484.1
CB037591.1
FK802534.1
JK315585.1
BXC01815_1
HCC00253_1
FK803029.1
FG980096.1
Oden_isotig04124
FK805791.1
EV852943.1
FK804898.1
FG971014.1
Oden_isotig04119
FF679283.1
FC819410.1
PT03551
Oden_isotig04123
FK805840.1
GW407100.1
HCC01420_1
HCC01809_1
CR11708
FK804250.1
EV851993.1
FG977243.1
ES672410.1
FK804630.1
FK807990.1
FG973265.1
EX555081.1
HBC02228_1
DN191309.1
ASC00061_1
CR09356
EV853326.1
FG975346.1
JI168684.1
Acan_isotig00550
EX547187.1
FK801563.1
FC818483.1
DN190525.1
FF681530.1
DVC00292_1
DVC02319_1
EX564501.1
NAC00357_1
Oden_isotig04116
ACC23816_1
CSC01120_1
FK803275.1
FK807510.1
HG09639
FK802763.1
PP02186
BXC01300_1
EX554922.1
FG977128.1
EX544797.1
Oden_isotig04114
PTC03622_1
FK808825.1
EV852182.1
CB037711.1
FG972369.1
XIC04341_1
Dviv_isotig03264
EX011642.1
FG978707.1
FC542181.1
HBC03195_1
FK804301.1
FG980697.1
HC08726
GP00595
HC00801
FK804228.1
Oden_isotig04115
DN190226.1
FG970991.1
FG972302.1
HCC03551_1
HCC01573_1
ACC23278_1
Tcol_isotig22608
FG974560.1
EX553185.1
HCC00346_1
GPC00176_1
DAC01740_1
FG980208.1
FC549293.1
CR06818
ES671927.1
FK808919.1
EY463461.1
OOC00124_1
FE916755.1
FK803744.1
AS15977
Name_isotig07939
FG978626.1
FG979161.1
CB038660.1
FF678274.1
FF680985.1
ES567266.1
FK809657.1
EX564460.1
HC02416
HBC03961_1
TS01162
Oden_isotig04125
FK809764.1
FG977941.1
FK805910.1
FG977832.1
Oden_isotig20237
EL890205.1
Oden_isotig04118
HC04488
FK803208.1
BG467552.1
HCC00022_1
HC08636
TDC01074_1
FG980164.1
FK803404.1
EY468761.1
Name_isotig03135
PVC02070_1
FK809989.1
HQ110099.1
FG980521.1
ACC21359_1
AS00443
HC02354
HCC05975_1
EX540267.1
HC03204
FK807970.1
HC03250
EV852900.1
FG980739.1
FG978220.1
EL888094.1
FC552995.1
FK800504.1
FK807827.1
FC548031.1
CB036358.1
PPC01211_1
FG976313.1
CB038077.1
HC00481
TSC09674_1
CB037428.1
FK800481.1
FK799974.1
FE916986.1
EX011252.1
FG979607.1
ACC01104_1
FK800527.1
AE04846
CB038114.1
FF678731.1
FK801606.1
FK800972.1
FC545489.1
FK804902.1
FK803366.1
ES411316.1
FG970820.1
HGC05717_1
TSC00307_1
CB038065.1
CB036624.1
EX562428.1
ACC26574_1
GW408128.1
FK800913.1
FG975119.1
EV853319.1
EV852080.1
Tcol_isotig14290
FG979884.1
EV851695.1
FK807400.1
FK800118.1
HC03198
Acan_isotig00549
FG979398.1
EX560802.1
Oden_isotig04121
Dviv_isotig03265
EV852960.1
Hbac_isotig00060
FK802077.1
CR02784
FG978322.1
FG980446.1
Dviv_isotig25584
CB036751.1
FD515103.1
AE03326
FF680563.1
AYC02908_1
FG976686.1
GW409702.1
GR19918
FK806091.1
FC548701.1
HC04958
EX551465.1
HC02215
FG979599.1
PSC00135
CRC00107_1
FK804298.1
HCC03479_1
EX007262.1
AAC00509_1
FK805059.1
HC00761
EX548072.1
FK802185.1
FG979834.1
FG979070.1
FG977791.1
FK808971.1
FC545598.1
FF678887.1
FC554241.1
AJ296151.1
Oden_isotig04113
FK804080.1
FG973076.1
FK800028.1
EY468029.1
AYC00612_1
HCC11109_1
FK800835.1
FK803027.1
FC548941.1
EV850936.1
ES672055.1
HCC03084_1
CBC00405_1
HCC06366_2
FK803712.1
EL888804.1
FK803724.1
FK805203.1
DN190230.1
EL890110.1
FC548502.1
EX541579.1
FK800753.1
FG978464.1
ES741935.1
NAC00700_1
ES413262.1
ACC01104_2
DA03701
FC550881.1
EV851488.1
EX552757.1
AS02435
FG974174.1
FK808162.1
DN190279.1
BU666851.1
PTC02845_1
HBC02472_1
HC00760
FG978543.1
SRC00430_1
FG972136.1
FF678921.1
HCC00019_1
ES672589.1
HCC01070_2
Dviv_isotig03272
HC06344
HC00750
JI173046.1
FG970869.1
CB037785.1
FK806419.1
ASC18598_1
FG971636.1
ACC08028_1
Tcir_isotig03375
EX566962.1
BU088129.1
FK806865.1
CB036910.1
FK803797.1
NB08417
FK806087.1
HC00045
FK800239.1
TDC01303_1
EV851872.1
FK802931.1
FK807015.1
EX010045.1
FD515736.1
PT04166
FK806717.1
FG978963.1
FK809399.1
PPC01541_1
Oden_isotig04128
Acan_isotig00551
FK802860.1
HBC00344_1
DN191303.1
Acan_isotig05502
FC553504.1
FK808205.1
EY458837.1
Oden_isotig12506
CRC06940_1
HC06377
EX559618.1
FF678032.1
FF678639.1
AE03318
EX549352.1
DN191353.1
EV853458.1
FG970901.1
FF678576.1
Oden_isotig19406
FK802691.1
Oden_isotig04126
HC02365
JI216814.1
ACC01104_3
FK804356.1
FC817418.1
Oden_contig24367
XI05214
EX912077.1
PP00378
HBC01944_1
BXC01444_1
FK801066.1
FK804942.1
NB07081
Dviv_isotig03269
DN557371.1
FG971477.1
BUC00002_1
FK804179.1
HCC02966_1
SR00895
FK803195.1
Dviv_isotig03266
FK809255.1
ES744050.1
FK809823.1
FG977410.1
TSC08085_1
GRC05371_1
EX910763.1
HC02448
FK806479.1
FG980001.1
ACC23816_2
EX008866.1
ES672267.1
ES672716.1
HC02329
FG972923.1
ES413158.1
HCC03572_1
FG972860.1
Dviv_isotig03271
FF678696.1
HCC06366_1
FK801488.1
EX557203.1
Tcir_isotig03374
HC02130
FK809877.1
CB037952.1
EL889215.1
Oden_isotig04112
Hbac_isotig06899
Oden_isotig04120
FK809623.1
FC554977.1
ES672612.1
EX536934.1
CB036357.1
FG973999.1
FC542615.1
HCC09542_1
EV851448.1
HC06463
FK801893.1
AE03740
FK802275.1
HBC23210_1
GPC00204_1
GPC00294_1
ACC03574_1
CJC00504_1
EX538728.1
Dviv_isotig03267
CB038303.1
FK803340.1
ES672699.1
FG976831.1
HS00611
FK807677.1
FG974870.1
ACC38117_1
FG974459.1
FC542495.1
EX544639.1
GW412004.1
GP00628
FD514675.1
FK804052.1
LSC00585_1
FK806978.1
DN190193.1
FK805445.1
Tcir_isotig24667
FK803927.1
CB038356.1
HCC00015_1
ES741388.1
Tcol_isotig12381
FF679233.1
FK803571.1
CRC05389_1
AYC01678_1
FG976156.1
FC817502.1
FC817474.1
ES672165.1
FK805761.1
EX560352.1
AE00478
FK806047.1
HC02449
DN190462.1
HCC11333_1
FK805814.1
FG977373.1
EX562029.1
FK800127.1
ES739503.1
ES568746.1
TDC00777_1
ES413288.1
FK805454.1
HCC10684_1
NBC00783_1
FF678305.1
FK807518.1
PVC02097_1
FK803246.1
FG980713.1
FG977346.1
EV851593.1
FG973262.1
ASC00061_2
CR11228
ES672453.1
EX539760.1
FK803333.1
ES672197.1
HC06516
ES672475.1
FG975672.1
Dviv_isotig03270
FC555509.1
Associated_featureWBsf648237
WBsf235856
Experimental_infoRNAi_resultWBRNAi00027664Inferred_automaticallyRNAi_primary
WBRNAi00076158Inferred_automaticallyRNAi_primary
WBRNAi00088992Inferred_automaticallyRNAi_primary
WBRNAi00115173Inferred_automaticallyRNAi_primary
WBRNAi00041163Inferred_automaticallyRNAi_primary
WBRNAi00086767Inferred_automaticallyRNAi_primary
WBRNAi00093243Inferred_automaticallyRNAi_primary
WBRNAi00011146Inferred_automaticallyRNAi_primary
Expr_patternExpr743
Expr1015929
Expr1030487
Expr1145192
Expr2010507
Expr2028747
Drives_constructWBCnstr00007422
WBCnstr00037276
Construct_productWBCnstr00007564
WBCnstr00037276
Microarray_results (33)
Expression_cluster (248)
Interaction (108)
Map_infoMapXPosition-2.73949Error0.013617
PositivePositive_cloneC25B8Author_evidenceLarminie CGC
Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4237
Pseudo_map_position
Reference (11)
Remarkdata received 11/94
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene