WormBase Tree Display for Gene: WBGene00000112

WBGene00000112 SMap: S_parent: Sequence: Y57G7A
  Identity: Version: 2
    Name: CGC_name: alh-6 Person_evidence: WBPerson651
      Sequence_name: F56D12.1
      Molecular_name (13)
      Other_name: xrep-2 Paper_evidence: WBPaper00051108
        CELE_F56D12.1 Accession_evidence: NDB BX284602
      Public_name: alh-6
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 16 May 2017 09:45:54 WBPerson2970 Name_change: Other_name: xrep-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: alh
    Allele (200)
    RNASeq_FPKM (74)
    GO_annotation (14)
    Contained_in_operon: CEOP2044
    Ortholog (43)
    Paralog (11)
    Structured_description: Concise_description: alh-6 is orthologous to the human gene ALDEHYDE DEHYDROGENASE 4 FAMILY, MEMBER A1 (ALDH4A1; OMIM:606811), which when mutated leads to hyperprolinemia type II. Curator_confirmed: WBPerson1823
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable 1-pyrroline-5-carboxylate dehydrogenase activity. Predicted to be involved in proline catabolic process to glutamate. Predicted to be located in mitochondrial matrix. Expressed in head and tail. Human ortholog(s) of this gene implicated in hyperprolinemia type 2. Is an ortholog of human ALDH4A1 (aldehyde dehydrogenase 4 family member A1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080543 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:406)
  Molecular_info: Corresponding_CDS: F56D12.1a
      F56D12.1b
      F56D12.1c
      F56D12.1d
    Corresponding_transcript: F56D12.1a.1
      F56D12.1a.2
      F56D12.1b.1
      F56D12.1c.1
      F56D12.1d.1
    Other_sequence: EX550623.1
      HCC09674_1
      AYC02886_1
      Acan_isotig07901
      OFC01683_1
      Tcol_isotig02064
      HGC01171_1
      FD515795.1
      CBC00021_1
      EX535600.1
      OF01268
      EX534515.1
      HSC01446_1
      PP01492
      AE03803
      CGC00088_1
      HC02003
      EY466051.1
      PPC00477_1
      FC545267.1
      FC541742.1
      CB299778.1
      OF01267
      FD517494.1
      ACC38064_1
      BXC07485_1
      FC544460.1
      Dviv_isotig14949
      CJC05786_1
      HS01347
      HC04580
      FK808616.1
      FC552657.1
      Oden_isotig08810
      EY468896.1
      BXC06891_1
      EX535210.1
      ACC21587_1
      HG08127
      ACC07842_1
      Oden_isotig08808
      EX535850.1
      Dviv_isotig14950
      FK803975.1
      Name_isotig02288
      Oden_isotig08809
      Tcir_isotig06613
      Oden_isotig08807
      Hbac_isotig02400
      Acan_isotig13782
      JI165882.1
      CSC00545_1
      Tcol_isotig17151
      FC552172.1
      Tcir_isotig02557
      OFC00244_1
      FC540750.1
      Tcol_isotig25505
      CJC00406_1
      EX565682.1
      HCC03152_1
      Tcir_isotig02556
      CBC07829_1
      EX555546.1
      ACC35431_1
      HG10251
      BM00482
      BMC17384_1
    Associated_feature (11)
  Experimental_info: RNAi_result (13)
    Expr_pattern: Chronogram1568
      Expr6220
      Expr1014020
      Expr1030059
      Expr1152446
      Expr2009308
      Expr2027544
    Drives_construct: WBCnstr00002586
    Regulate_expr_cluster: WBPaper00059231:alh-6(lax105)_D3Adult_downregulated
      WBPaper00059231:alh-6(lax105)_D3Adult_upregulated
      WBPaper00059231:alh-6(lax105)_L4_downregulated
      WBPaper00059231:alh-6(lax105)_L4_upregulated
    Microarray_results (44)
    Expression_cluster (137)
    Interaction (68)
  Map_info: Map: II Position: -15.5079 Error: 0.004302
    Positive: Positive_clone: F56D12 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00040958
    WBPaper00041713
    WBPaper00042257
    WBPaper00044733
    WBPaper00045841
    WBPaper00047646
    WBPaper00051108
    WBPaper00052171
    WBPaper00055090
    WBPaper00057533
    WBPaper00060917
    WBPaper00062816
    WBPaper00063995
    WBPaper00064934
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene