WormBase Tree Display for Gene: WBGene00206487

WBGene00206487 SMap: S_parent: Sequence: T21D12
  Identity: Version: 2
    Name: CGC_name: best-19 Person_evidence: WBPerson260
      Sequence_name: T21D12.15
      Molecular_name: T21D12.15
        T21D12.15.1
        CE37724
      Other_name: CELE_T21D12.15 Accession_evidence: NDB BX284604
      Public_name: best-19
    DB_info: Database: WormFlux gene WBGene00206487
        NDB locus_tag CELE_T21D12.15
        Panther gene CAEEL|WormBase=WBGene00206487|UniProtKB=O16779
          family PTHR10736
        NCBI gene 13191891
        RefSeq protein NM_001268290.3
        TrEMBL UniProtAcc O16779
        UniProt_GCRP UniProtAcc O16779
        OMIM gene 607854
    Species: Caenorhabditis elegans
    History: Version_change: 1 13 Jun 2011 13:21:04 WBPerson1849 Event: Split_from: WBGene00020649
        2 07 Feb 2012 16:30:56 WBPerson2970 Name_change: CGC_name: best-19
      Split_from: WBGene00020649
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: best
    Allele (38)
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog: WBGene00034260 Caenorhabditis briggsae From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00072003 Caenorhabditis remanei From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00095980 Pristionchus pacificus From_analysis: Inparanoid_8
      WBGene00194046 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      CBOVI.g8606 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP26.g14305 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g2647 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g22225 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g6389 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g14011 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g3432 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g10580 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g7050 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g23922 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cni-best-19 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g10676 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_03040.g28870 Caenorhabditis sinica From_analysis: WormBase-Compara
      Csp5_scaffold_07746.g38097 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_25021 Caenorhabditis latens From_analysis: WormBase-Compara
      FL83_25144 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_016199 Caenorhabditis remanei From_analysis: WormBase-Compara
      Sp34_40018500 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g9478 Caenorhabditis elegans From_analysis: WormBase-Compara
      FB:FBgn0035696 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
      FB:FBgn0036491 Drosophila melanogaster From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
      FB:FBgn0036492 Drosophila melanogaster From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
      FB:FBgn0040238 Drosophila melanogaster From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
      ZFIN:ZDB-GENE-110411-214 Danio rerio From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      ZFIN:ZDB-GENE-070912-6 Danio rerio From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      HGNC:12703 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
      HGNC:17107 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
      HGNC:17105 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
      HGNC:17106 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
      MGI:1346332 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      MGI:2387588 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      MGI:3580298 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      RGD:1311656 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      RGD:1305439 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      RGD:1305377 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      RGD:1596200 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
    Paralog (26)
    Structured_description: Automated_description: Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0110396 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:4448 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:0050661 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:0050662 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:0111569 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
  Molecular_info: Corresponding_CDS: T21D12.15
    Corresponding_transcript: T21D12.15.1
    Other_sequence (23)
  Experimental_info: Expr_pattern: Expr1040508
      Expr1157280
      Expr2009600
      Expr2027837
    Microarray_results (15)
    Expression_cluster (49)
  Map_info: Map: IV Position: -26.6798
    Positive: Positive_clone: T21D12 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene