WormBase Tree Display for Gene: WBGene00021553

WBGene00021553 SMap: S_parent: Sequence: CHROMOSOME_I
  Identity: Version: 2
    Name: CGC_name: tyr-5 Person_evidence: WBPerson260
      Sequence_name: Y44E3B.2
      Molecular_name: Y44E3B.2
        Y44E3B.2.1
        CE39838
      Other_name: CELE_Y44E3B.2 Accession_evidence: NDB BX284601
      Public_name: tyr-5
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:04 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 28 Jan 2010 16:20:10 WBPerson2970 Name_change: CGC_name: tyr-5
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: tyr
    Allele (74)
    RNASeq_FPKM (74)
    GO_annotation: 00038649
      00125882
    Ortholog: WBGene00035349 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00056411 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00105089 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00128797 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00192877 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      CBOVI.g10213 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g9882 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g17675 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g3349 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g1782 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g8362 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g9582 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g22154 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g5312 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g23512 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00042.g2314 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-tyr-5 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold627.g6826 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00701.g14568 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_13904 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_002094 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g06727 Oscheius tipulae From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g10541 Oscheius tipulae From_analysis: WormBase-Compara
      Sp34_10174610 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g484 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00213030 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00091242 Pristionchus pacificus From_analysis: WormBase-Compara
      ZFIN:ZDB-GENE-991026-3 Danio rerio From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-000508-1 Danio rerio From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-040718-249 Danio rerio From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-070718-2 Danio rerio From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:12442 Homo sapiens From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:12450 Homo sapiens From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:102563 Mus musculus From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:98880 Mus musculus From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:98881 Mus musculus From_analysis: Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1593266 Rattus norvegicus From_analysis: OrthoFinder
            OrthoInspector
            Panther
      RGD:1589755 Rattus norvegicus From_analysis: OrthoFinder
            OrthoInspector
            Panther
    Paralog (7)
    Structured_description: Automated_description: Predicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including ocular albinism 1; oculocutaneous albinism (multiple); and vitiligo. Is an ortholog of human TYR (tyrosinase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0050633 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12442)
      DOID:8465 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12442)
      DOID:0070097 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12450)
      DOID:0050632 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12442,HGNC:12450)
      DOID:8923 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12442)
      DOID:12306 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12442)
      DOID:0070095 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12442)
      DOID:0070094 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12442)
      DOID:1909 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12442)
      DOID:10123 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12442,HGNC:12450)
  Molecular_info: Corresponding_CDS: Y44E3B.2
    Corresponding_CDS_history: Y44E3B.2:wp154
    Corresponding_transcript: Y44E3B.2.1
    Other_sequence (11)
    Associated_feature: WBsf983096
  Experimental_info: RNAi_result: WBRNAi00112664 Inferred_automatically: RNAi_primary
      WBRNAi00056562 Inferred_automatically: RNAi_primary
      WBRNAi00004620 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1020061
      Expr1160035
      Expr2017689
      Expr2035827
    Microarray_results (20)
    Expression_cluster (124)
    Interaction (25)
  Map_info: Map: I Position: -4.25528 Error: 0.043092
    Positive: Positive_clone: Y44E3B Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00064934
    WBPaper00065140
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene