WormBase Tree Display for Gene: WBGene00013866

WBGene00013866 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 2
    Name: CGC_name: cbs-1 Paper_evidence: WBPaper00039977
          Person_evidence: WBPerson537
      Sequence_name: ZC373.1
      Molecular_name: ZC373.1a
        ZC373.1a.1
        CE31670
        ZC373.1b
        CE47092
        ZC373.1b.1
      Other_name: CELE_ZC373.1 Accession_evidence: NDB BX284606
      Public_name: cbs-1
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:55 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 29 Sep 2011 10:45:56 WBPerson2970 Name_change: CGC_name: cbs-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cbs
    Allele (32)
    Strain: WBStrain00002826
      WBStrain00052082
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog: WBGene00063142 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00025101 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00150974 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00124490 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00104153 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00224592 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g11841 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g15474 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g268 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g17671 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g20558 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g25059 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g12699 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g9436 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g5698 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g15918 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00065.g3165 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_X.g22936 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g13655 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00147.g5631 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_01405 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_023510 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g07477 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g10675 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_X0064000 Caenorhabditis inopinata From_analysis: WormBase-Compara
      Sp34_X0064200 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrX_pilon.g19838 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00239784 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00258231 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00259867 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00284919 Trichuris muris From_analysis: WormBase-Compara
      WBGene00293374 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000003387 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0031148 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-021030-3 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-050417-367 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:1550 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:CBSL Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:88285 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:2287 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
    Paralog (12)
    Structured_description: Concise_description: cbs-1 encodes an ortholog of human CYSTATHIONINE-BETA-SYNTHASE (CBS), which when mutated leads to homocystinuria (OMIM:236200). Paper_evidence: WBPaper00004637
          Curator_confirmed: WBPerson1823
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables cystathionine beta-synthase activity; cysteine synthase activity; and pyridoxal phosphate binding activity. Involved in sulfur compound biosynthetic process. Located in cytoplasm. Expressed in pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including homocystinuria; hyperhomocysteinemia; and neural tube defect. Is an ortholog of human CBS (cystathionine beta-synthase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080074 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1550)
      DOID:12365 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1550)
      DOID:9279 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1550)
      DOID:9263 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1550)
      DOID:3526 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1550)
      DOID:3393 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1550)
  Molecular_info: Corresponding_CDS: ZC373.1a
      ZC373.1b
    Corresponding_CDS_history: ZC373.1:wp83
    Corresponding_transcript: ZC373.1a.1
      ZC373.1b.1
    Other_sequence (40)
    Associated_feature: WBsf648441
      WBsf655205
      WBsf1006596
      WBsf236234
  Experimental_info: RNAi_result: WBRNAi00058845 Inferred_automatically: RNAi_primary
      WBRNAi00091457 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1051
      Expr7160
      Expr9921
      Expr1018878
      Expr1036202
      Expr1162289
      Expr2009744
      Expr2027984
    Drives_construct (3)
    Construct_product: WBCnstr00014401
      WBCnstr00016327
      WBCnstr00029491
    Antibody: WBAntibody00002306
    Microarray_results (22)
    Expression_cluster (173)
    Interaction (63)
  Map_info: Map: X Position: 1.73547
    Positive: Positive_clone: ZC373 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00034443
    WBPaper00038491
    WBPaper00040475
    WBPaper00040626
    WBPaper00055090
    WBPaper00059856
    WBPaper00059949
    WBPaper00060431
    WBPaper00060693
    WBPaper00064989
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene