WormBase Tree Display for Gene: WBGene00007135

WBGene00007135 SMap: S_parent: Sequence: B0285
  Identity: Version: 4
    Name: CGC_name: cdk-12 Person_evidence: WBPerson313
            WBPerson3232
            WBPerson555
      Sequence_name: B0285.1
      Molecular_name (12)
      Other_name: cdtl-7 Person_evidence: WBPerson3232
            WBPerson555
        CELE_B0285.1 Accession_evidence: NDB BX284603
      Public_name: cdk-12
    DB_info: Database (14)
    Species: Caenorhabditis elegans
    History: Version_change (4)
      Acquires_merge: WBGene00043080
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cdk
    Allele (122)
    Strain: WBStrain00003574
      WBStrain00024046
      WBStrain00024054
      WBStrain00024069
      WBStrain00024070
      WBStrain00037602
    RNASeq_FPKM (74)
    GO_annotation (24)
    Ortholog: WBGene00061799 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            WormBase-Compara
      WBGene00037579 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            WormBase-Compara
      WBGene00160738 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00092113 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00221996 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g5454 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g8393 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g5644 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g20527 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g16775 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g5192 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g4909 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g449 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g16506 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g20743 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00260.g8042 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-cdk-12 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g21924 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01767.g23014 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_14986 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_010122 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g03991 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g14788 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_30076500 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g7423 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00245379 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00261676 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00302699 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000001622 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      FB:FBgn0037093 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-081104-294 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-4975 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:1733 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:24224 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1098802 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1916812 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:621111 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1311226 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog (17)
    Structured_description: Automated_description: Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin binding activity. Involved in nematode larval development. Part of euchromatin. Expressed in several structures, including germ line and head. Human ortholog(s) of this gene implicated in several diseases, including breast cancer; carcinoma (multiple); and congenital heart defects, dysmorphic facial features, and intellectual developmental disorder. Is an ortholog of human CDK13 (cyclin dependent kinase 13). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0112247 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1733)
      DOID:10534 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:24224)
      DOID:10286 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1733)
      DOID:3717 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:24224)
      DOID:10283 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1733)
      DOID:684 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1733,HGNC:24224)
      DOID:1059 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1733)
      DOID:1612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1733)
  Molecular_info: Corresponding_CDS: B0285.1a
      B0285.1b
      B0285.1c
    Corresponding_CDS_history: B0285.1:wp23
      B0285.1:wp83
    Corresponding_transcript: B0285.1a.1
      B0285.1a.2
      B0285.1b.1
      B0285.1b.2
      B0285.1c.1
      B0285.1c.2
    Other_sequence (19)
    Associated_feature (11)
  Experimental_info: RNAi_result (56)
    Expr_pattern: Chronogram501
      Expr5038
      Expr11660
      Expr1020850
      Expr1033070
      Expr1143059
      Expr2009808
      Expr2028049
    Drives_construct: WBCnstr00004026
      WBCnstr00033974
    Construct_product: WBCnstr00019156
      WBCnstr00019285
      WBCnstr00019286
      WBCnstr00019287
      WBCnstr00033974
    Microarray_results (26)
    Expression_cluster (96)
    Interaction (92)
  Map_info: Map: III Position: -3.18675 Error: 0.000933
    Positive: Positive_clone: B0285 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027258
    WBPaper00031224
    WBPaper00032961
    WBPaper00038491
    WBPaper00044000
    WBPaper00047409
    WBPaper00055090
    WBPaper00060756
    WBPaper00063946
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    [140610 pad] Gene was missing Acquires_merge Event history data so inferred from Acquires_merge tag.
  Method: Gene