prx-19 is orthologous to the human gene PEROXISOMAL FARNESYLATED PROTEIN (PXF; OMIM:600279), which when mutated leads to peroxisome biogenesis (Zellweger) syndrome of complementation group J.
Predicted to enable peroxisome membrane targeting sequence binding activity. Involved in nematode larval development. Predicted to be located in peroxisomal membrane. Expressed in pharynx. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 12A. Is an ortholog of human PEX19 (peroxisomal biogenesis factor 19).
Note that some Authors have incorrectly published prx genes as pex genes. pex genes are a separate class of gene not related to prx genes [JAH][030108 ck1]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.