WormBase Tree Display for Gene: WBGene00001579

WBGene00001579 SMap: S_parent: Sequence: CHROMOSOME_IV
  Identity: Version: 1
    Name: CGC_name: gex-2 Person_evidence: WBPerson419
      Sequence_name: F56A11.1
      Molecular_name: F56A11.1
        F56A11.1.1
        CE31351
      Other_name: CELE_F56A11.1 Accession_evidence: NDB BX284604
      Public_name: gex-2
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gex
    Allele (162)
    Strain: WBStrain00036391
    RNASeq_FPKM (74)
    GO_annotation (22)
    Ortholog: WBGene00059480 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00024826 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00096764 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00175050 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
      WBGene00130775 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00191261 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00192277 Caenorhabditis brenneri From_analysis: WormBase-Compara
      WBGene00224715 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g11315 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g15875 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP21.g15877 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g11755 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP26.g11757 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g7030 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g7153 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g12735 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP31.g12737 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g12839 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g2345 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g9368 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g12958 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00135.g5298 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_04086.g18594 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_10195.g22512 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_IV.g14721 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g7564 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01155.g18834 Caenorhabditis sinica From_analysis: WormBase-Compara
      Csp5_scaffold_01155.g18836 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_16354 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_014695 Caenorhabditis remanei From_analysis: WormBase-Compara
      GCK72_014697 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g10494 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g18017 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_40113810 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g9526 Caenorhabditis elegans From_analysis: WormBase-Compara
      chrIV_pilon.g9528 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00080667 Caenorhabditis remanei From_analysis: WormBase-Compara
      WBGene00237796 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00259548 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00266369 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00292619 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0038320 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-030131-8557 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-080724-2 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:13759 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:13760 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1338801 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1924134 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1305048 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1310332 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Concise_description: The gex-2 gene encodes a homolog of p140/Sra-1, a mammalian protein ligand of the small GTPase Rac1; gex-2 is required for tissue morphogenesis and cell migrations. Paper_evidence: WBPaper00005149
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable RNA 7-methylguanosine cap binding activity. Involved in several processes, including embryonic body morphogenesis; positive regulation of clathrin-dependent endocytosis; and positive regulation of egg-laying behavior. Located in cell junction. Part of SCAR complex. Human ortholog(s) of this gene implicated in several diseases, including Schaaf-Yang syndrome; autism spectrum disorder; and epilepsy (multiple). Is an ortholog of human CYFIP1 (cytoplasmic FMR1 interacting protein 1) and CYFIP2 (cytoplasmic FMR1 interacting protein 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111715 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:13759)
      DOID:0080430 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:13760)
      DOID:0060041 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:13759)
      DOID:3328 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:13759)
      DOID:5419 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:13759)
  Molecular_info: Corresponding_CDS: F56A11.1
    Corresponding_CDS_history: F56A11.1:wp129
    Corresponding_transcript: F56A11.1.1
    Other_sequence (56)
    Associated_feature (8)
  Experimental_info: RNAi_result (33)
    Expr_pattern: Expr1827
      Expr1026712
      Expr1030945
      Expr1152359
      Expr2012023
      Expr2030259
    Drives_construct: WBCnstr00036849
    Construct_product: WBCnstr00036849
    Antibody: WBAntibody00000462
      WBAntibody00000463
    Microarray_results (20)
    Expression_cluster (133)
    Interaction (42)
  Map_info: Map: IV Position: -24.7527 Error: 0.274792
    Positive: Positive_clone: F56A11 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5641
    Pseudo_map_position
  Reference (36)
  Remark: the 3' end is on C18H7 (nucleotides 1 to 3,000)
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene