WormBase Tree Display for Gene: WBGene00001160

WBGene00001160 SMap: S_parent: Sequence: F42A10
  Identity: Version: 1
    Name: CGC_name: efk-1 Person_evidence: WBPerson145
      Sequence_name: F42A10.4
      Molecular_name: F42A10.4a
        F42A10.4a.1
        CE32415
        F42A10.4b
        CE32416
        F42A10.4b.1
      Other_name: efk1 Accession_evidence: EMBL U93846
              U93847
        CELE_F42A10.4 Accession_evidence: NDB BX284603
      Public_name: efk-1
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:23 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: efk
    Allele (53)
    Legacy_information: [Ryazanov AG] efk for Elongation Factor Kinase. No mutants known. Encodes EFK-1A and EFK-1B, two products produced by alternative splicing, EFK-1B omits exon IV. C. elegans homolog of mammalian elongation factor-2 kinase (eEF-2 kinase).
    Strain: WBStrain00033263
    RNASeq_FPKM (74)
    GO_annotation (14)
    Contained_in_operon: CEOP3900
    Ortholog: WBGene00055388 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00039967 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00151863 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00123308 Caenorhabditis japonica From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00224280 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g4754 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g10555 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP21.g11961 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP21.g8332 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g6005 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g11317 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g16211 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g17331 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g6795 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g17325 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g2666 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g11242 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00503.g11618 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-efk-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold596.g5275 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00814.g15721 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_08838 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_010810 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g01655 Oscheius tipulae From_analysis: WormBase-Compara
      Sp34_30148600 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g7869 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00212668 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00242547 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00265119 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00266382 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00291551 Trichuris muris From_analysis: WormBase-Compara
      ZFIN:ZDB-GENE-020916-2 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:24615 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1195261 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:2538 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Concise_description: efk-1 encodes a calcium/calmodulin-dependent protein kinase with homology to human elongation factor-2 kinase; expressed in only a few cells in embryos. Paper_evidence: WBPaper00002841
            WBPaper00017814
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables elongation factor-2 kinase activity. Predicted to be involved in myosin II filament disassembly. Human ortholog(s) of this gene implicated in Alzheimer's disease and lung adenocarcinoma. Is an ortholog of human EEF2K (eukaryotic elongation factor 2 kinase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS292 version of WormBase
          Date_last_updated: 24 Apr 2024 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:24615)
      DOID:3910 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:24615)
  Molecular_info: Corresponding_CDS: F42A10.4a
      F42A10.4b
    Corresponding_CDS_history: F42A10.4a:wp88
      F42A10.4b:wp88
    Corresponding_transcript: F42A10.4a.1
      F42A10.4b.1
    Other_sequence (23)
    Associated_feature: WBsf666972
      WBsf226772
      WBsf226773
  Experimental_info: RNAi_result: WBRNAi00005317 Inferred_automatically: RNAi_primary
      WBRNAi00014792 Inferred_automatically: RNAi_primary
      WBRNAi00047057 Inferred_automatically: RNAi_primary
      WBRNAi00115388 Inferred_automatically: RNAi_primary
      WBRNAi00097655 Inferred_automatically: RNAi_primary
      WBRNAi00000356 Inferred_automatically: RNAi_primary
      WBRNAi00027708 Inferred_automatically: RNAi_primary
      WBRNAi00098182 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr2042
      Expr1014472
      Expr1030738
      Expr1150920
      Expr2011188
      Expr2029424
    Drives_construct: WBCnstr00037056
    Construct_product: WBCnstr00037056
    Microarray_results (27)
    Expression_cluster (117)
    Interaction (51)
  Map_info: Map: III Position: -1.41114 Error: 0.000417
    Positive: Positive_clone: F42A10 Person_evidence: WBPerson5884
          Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (16)
  Remark: See Ryazanov et al. (1997)
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene