WormBase Tree Display for Gene: WBGene00000784

WBGene00000784 SMap: S_parent: Sequence: F44C4
  Identity: Version: 1
    Name: CGC_name: cpr-4
      Sequence_name: F44C4.3
      Molecular_name: F44C4.3
        F44C4.3.1
        CE07251
      Other_name: CELE_F44C4.3 Accession_evidence: NDB BX284605
      Public_name: cpr-4
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cpr
    Allele (33)
    Legacy_information: [C.elegansII] NMK. Encodes protein with significant similarity to proteases of Cathepsin B family (EST cm14e3). [IA]
    Strain: WBStrain00033148
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog: WBGene00052192 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00038270 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00161299 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00130220 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00101869 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
      WBGene00221927 Brugia malayi From_analysis: WormBase-Compara
      WBGene00227936 Brugia malayi From_analysis: WormBase-Compara
      WBGene00227937 Brugia malayi From_analysis: WormBase-Compara
      WBGene00227938 Brugia malayi From_analysis: WormBase-Compara
      WBGene00227940 Brugia malayi From_analysis: WormBase-Compara
      WBGene00227942 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g2285 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g13149 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP21.g9653 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g20007 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g8713 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g5480 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g11271 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g14934 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g20698 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g12052 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g4532 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g11382 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00390.g10171 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_22373.g26845 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-cpr-4 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold601.g5420 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00013.g876 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_10814 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_017963 Caenorhabditis remanei From_analysis: WormBase-Compara
      Pan_g10438 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g1472 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g2142 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_50216800 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrV_pilon.g14478 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00273832 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00288835 Trichuris muris From_analysis: WormBase-Compara
      WBGene00288836 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0030521 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            OMA
            OrthoFinder
            Panther
      ZFIN:ZDB-GENE-040426-2650 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-070323-1 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:2527 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
      MGI:88561 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
      RGD:621509 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
    Paralog (28)
    Structured_description: Concise_description: cpr-4 encodes a cathepsin B-like cysteine protease expressed at all life stages. Paper_evidence: WBPaper00002373
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables cysteine-type endopeptidase activity. Involved in cellular response to UV; cellular response to gamma radiation; and proteolysis involved in protein catabolic process. Located in extracellular region. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9351 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:11054 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:2671 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:9352 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:2377 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:10941 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:12842 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:3068 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:4914 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:1612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
  Molecular_info: Corresponding_CDS: F44C4.3
    Corresponding_transcript: F44C4.3.1
    Other_sequence (375)
    Associated_feature: WBsf646890
      WBsf1000314
      WBsf231894
  Experimental_info: RNAi_result: WBRNAi00007344 Inferred_automatically: RNAi_primary
      WBRNAi00115171 Inferred_automatically: RNAi_primary
      WBRNAi00047258 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr741
      Expr13281
      Expr1014351
      Expr1030485
      Expr1151114
      Expr2010505
      Expr2028745
    Drives_construct: WBCnstr00037278
      WBCnstr00039152
    Construct_product: WBCnstr00037278
    Microarray_results (19)
    Expression_cluster (354)
    Interaction (146)
  Map_info (3)
  Reference (15)
  Remark: data received 11/94
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene