WormBase Tree Display for Gene: WBGene00000214

WBGene00000214 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: Y39B6A
  Identity (6)
  Gene_info: Biotype: SO:0001217
    Gene_class: asp
    Allele (35)
    Strain: WBStrain00001516
    RNASeq_FPKM (74)
    GO_annotation (18)
    Ortholog: WBGene00039339 Caenorhabditis briggsae From_analysis: OrthoMCL
            Inparanoid_8
            WormBase-Compara
      WBGene00156488 Caenorhabditis brenneri From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00125298 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00063407 Caenorhabditis remanei From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00105997 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00106393 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00111789 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00223753 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g2066 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g15581 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g19072 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g7219 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g19247 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g26135 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g3216 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g7941 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g7181 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g12061 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_28350.g27640 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_V.g21705 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp5_scaffold_01782.g23114 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_16281 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_021589 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g09909 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g11252 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g316 Panagrellus redivivus From_analysis: WormBase-Compara
      chrV_pilon.g17812 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00244151 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00244157 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00115380 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00115381 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00278598 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00278974 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00279465 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00279739 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00258196 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00288389 Trichuris muris From_analysis: WormBase-Compara
      WBGene00288391 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000004110 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      SGD:S000004111 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      SGD:S000002551 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      SGD:S000001277 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      SGD:S000001478 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            OrthoFinder
            SonicParanoid
      SGD:S000006075 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Panther
            SonicParanoid
      FB:FBgn0011822 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            OMA
            Panther
      FB:FBgn0032303 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
            PhylomeDB
      FB:FBgn0051926 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            OMA
            Panther
      FB:FBgn0051928 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            OMA
            Panther
      ZFIN:ZDB-GENE-010620-1 Danio rerio From_analysis: EnsEMBL-Compara
            Panther
      ZFIN:ZDB-GENE-040630-3 Danio rerio From_analysis: EnsEMBL-Compara
            Panther
      HGNC:8890 Homo sapiens From_analysis: EnsEMBL-Compara
            OMA
      HGNC:9958 Homo sapiens From_analysis: EnsEMBL-Compara
            Panther
      MGI:109365 Mus musculus From_analysis: EnsEMBL-Compara
            Panther
      MGI:97898 Mus musculus From_analysis: EnsEMBL-Compara
            Panther
      MGI:97899 Mus musculus From_analysis: EnsEMBL-Compara
            Panther
      MGI:98909 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
      RGD:708486 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            Panther
    Paralog (18)
    Structured_description: Concise_description: asp-1 encodes a homolog of cathepsin D aspartic protease; it is transcribed exclusively in intestinal cells of the late embryo and early larvae and is not observed in older larvae or adults; ASP-1 is dispensable for neuronal degeneration. Paper_evidence: WBPaper00004299
            WBPaper00005513
          Curator_confirmed: WBPerson324
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Located in cytoplasm and external side of apical plasma membrane. Expressed in intestinal cell and intestine. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); chronic fatigue syndrome; and congenital adrenal hyperplasia. Is an ortholog of human PGC (progastricsin) and REN (renin). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (17)
  Molecular_info: Corresponding_CDS: Y39B6A.20
    Corresponding_transcript: Y39B6A.20.1
    Other_sequence (155)
    Associated_feature (18)
  Experimental_info: RNAi_result (17)
    Expr_pattern (12)
    Drives_construct: WBCnstr00002373
      WBCnstr00010076
      WBCnstr00022452
      WBCnstr00037658
    Construct_product: WBCnstr00010076
      WBCnstr00022452
      WBCnstr00037658
    Antibody: WBAntibody00000301
    Microarray_results (20)
    Expression_cluster (284)
    Interaction (49)
    WBProcess: WBbiopr:00000134
  Map_info: Map: V Position: 18.5005 Error: 0.138896
    Positive: Positive_clone: Y39B6A Inferred_automatically: From sequence, transcript, pseudogene data
        Y39B6B
    Mapping_data: Multi_point: 4527
        5346
    Pseudo_map_position
  Reference (31)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene