WormBase Tree Display for Gene: WBGene00000181

WBGene00000181 SMap: S_parent: Sequence: F01G4
  Identity: Version: 1
    Name: CGC_name: ard-1
      Sequence_name: F01G4.2
      Molecular_name (6)
      Other_name: CELE_F01G4.2 Accession_evidence: NDB BX284604
      Public_name: ard-1
    DB_info: Database: AceView gene 4L897
        WormQTL gene WBGene00000181
        WormFlux gene WBGene00000181
        NDB locus_tag CELE_F01G4.2
        Panther gene CAEEL|WormBase=WBGene00000181|UniProtKB=Q19102
          family PTHR43658
        NCBI gene 178016
        RefSeq protein NM_001307064.3
            NM_069682.8
        TrEMBL UniProtAcc Q19102
            A0A061AD09
        UniProt_GCRP UniProtAcc Q19102
        OMIM gene 300256
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ard
    Allele (29)
    Strain: WBStrain00049398
    RNASeq_FPKM (74)
    GO_annotation: 00000186
      00000187
      00000188
      00000189
      00000190
      00000191
    Contained_in_operon: CEOP4412
    Ortholog: WBGene00062537 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00028363 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00158369 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00110000 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00075958 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00076563 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00192477 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      WBGene00074924 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00121446 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00223398 Brugia malayi From_analysis: WormBase-Compara
      WBGene00223492 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g11502 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g5794 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g15752 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g2370 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g13609 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g4858 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g13943 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g3386 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g16524 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g2654 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g17276 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_07716.g21069 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_18016.g25858 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-ard-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g8038 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00125.g5004 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_12815 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_014065 Caenorhabditis remanei From_analysis: WormBase-Compara
      GCK72_014228 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g03012 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g15184 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g15185 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_40314500 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g11779 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00242228 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00257023 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00293579 Trichuris muris From_analysis: WormBase-Compara
      WBGene00296173 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0021765 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-041010-201 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:4800 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1333871 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:69231 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog (38)
    Structured_description: Concise_description: ard-1 encodes a homolog of mammalian 3-hydroxyacyl-CoA dehydrogenase (HADH II)/amyloid-beta binding alcohol dehydrogenase (ABAD) that is predicted to be mitochondrial. Paper_evidence: WBPaper00004424
            WBPaper00012828
            WBPaper00013599
            WBPaper00013615
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable estradiol 17-beta-dehydrogenase [NAD(P)] activity. Predicted to be involved in androgen metabolic process; estrogen metabolic process; and fatty acid metabolic process. Predicted to be located in mitochondrion. Expressed in hypodermis. Human ortholog(s) of this gene implicated in Alzheimer's disease; osteosarcoma; pheochromocytoma; and syndromic X-linked intellectual disability type 10. Is an ortholog of human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4800)
      DOID:3347 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4800)
      DOID:0060810 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4800)
      DOID:0050771 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4800)
  Molecular_info: Corresponding_CDS: F01G4.2a
      F01G4.2b
    Corresponding_transcript: F01G4.2a.1
      F01G4.2b.1
    Other_sequence (74)
    Associated_feature: WBsf997771
      WBsf997772
      WBsf1018176
      WBsf229103
      WBsf229104
  Experimental_info: RNAi_result: WBRNAi00025001 Inferred_automatically: RNAi_primary
      WBRNAi00027256 Inferred_automatically: RNAi_primary
      WBRNAi00043779 Inferred_automatically: RNAi_primary
      WBRNAi00076269 Inferred_automatically: RNAi_primary
      WBRNAi00012757 Inferred_automatically: RNAi_primary
      WBRNAi00102583 Inferred_automatically: RNAi_primary
      WBRNAi00030558 Inferred_automatically: RNAi_primary
      WBRNAi00102692 Inferred_automatically: RNAi_primary
      WBRNAi00102683 Inferred_automatically: RNAi_primary
      WBRNAi00102674 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr8141
      Expr12157
      Expr1024424
      Expr1030105
      Expr1147756
      Expr2009389
      Expr2027625
    Drives_construct: WBCnstr00013141
      WBCnstr00020295
      WBCnstr00037681
    Construct_product: WBCnstr00037681
    Microarray_results (21)
    Expression_cluster (112)
    Interaction (60)
  Map_info: Map: IV Position: 4.90778
    Positive: Positive_clone: F01G4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00026640
    WBPaper00026800
    WBPaper00028352
    WBPaper00031915
    WBPaper00038491
    WBPaper00041771
    WBPaper00042257
    WBPaper00055090
    WBPaper00062444
    WBPaper00062625
  Remark: The name sad was previously used for this Short-chain Alcohol Dehydrogenase ERAB family by Carl Johnson.
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene