WormBase Tree Display for Gene: WBGene00016173

WBGene00016173 SMap: S_parent: Sequence: C27H5
  Identity: Version: 2
    Name: CGC_name: fust-1 Person_evidence: WBPerson1352
      Sequence_name: C27H5.3
      Molecular_name: C27H5.3a
        C27H5.3a.1
        CE27099
        C27H5.3b
        CE51847
        C27H5.3b.1
        C27H5.3b.2
      Other_name: CELE_C27H5.3 Accession_evidence: NDB BX284602
      Public_name: fust-1
    DB_info: Database: AceView gene 2H445
        WormQTL gene WBGene00016173
        WormFlux gene WBGene00016173
        NDB locus_tag CELE_C27H5.3
        Panther gene CAEEL|WormBase=WBGene00016173|UniProtKB=Q18265
          family PTHR23238
        NCBI gene 174175
        RefSeq protein NM_063082.7
            NM_001381492.1
        TrEMBL UniProtAcc Q18265
            A0A1N7SYQ6
        UniProt_GCRP UniProtAcc Q18265
        OMIM gene 133450
            137070
            601574
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:57 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 03 Aug 2010 10:05:58 WBPerson2970 Name_change: CGC_name: fust-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: fust
    Allele (42)
    Strain: WBStrain00001567
      WBStrain00047288
      WBStrain00047287
      WBStrain00047289
      WBStrain00050865
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog: WBGene00033904 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00054275 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00147824 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00123406 Caenorhabditis japonica From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00222701 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g6159 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g11789 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP21.g26 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP21.g5396 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP21.g786 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP21.g8889 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g4389 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g12147 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g9312 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP32.g4268 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g5121 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g3820 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g8386 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00897.g14818 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_II.g5279 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g12150 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00758.g15185 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_09502 Caenorhabditis latens From_analysis: WormBase-Compara
      FL83_16993 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_006432 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g10168 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g22121 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_20262200 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrII_pilon.g4951 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00237261 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00304615 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00267463 Strongyloides ratti From_analysis: WormBase-Compara
      FB:FBgn0285954 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            Panther
            SonicParanoid
      FB:FBgn0037939 Drosophila melanogaster From_analysis: OrthoFinder
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-030131-1600 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-030131-2317 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-040426-1010 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-061215-102 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            Panther
            SonicParanoid
      HGNC:3508 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            SonicParanoid
      HGNC:4010 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:11547 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            Panther
            SonicParanoid
      MGI:99960 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            SonicParanoid
      MGI:1917689 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            Panther
            SonicParanoid
      MGI:1353633 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1309595 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            Panther
            SonicParanoid
      RGD:1307258 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            SonicParanoid
      RGD:1308864 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Automated_description: Predicted to enable RNA binding activity and transcription coregulator activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in gonad; head; intestinal cell; neurons; and tail. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 6; connective tissue cancer (multiple); and essential tremor 4. Is an ortholog of human FUS (FUS RNA binding protein). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:1289 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4010)
      DOID:0111431 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4010)
      DOID:0060198 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4010)
      DOID:4549 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11547)
      DOID:1115 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4010)
      DOID:332 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4010)
      DOID:3382 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4010)
      DOID:3371 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11547)
      DOID:3369 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3508)
  Molecular_info: Corresponding_CDS: C27H5.3a
      C27H5.3b
    Corresponding_transcript: C27H5.3a.1
      C27H5.3b.1
      C27H5.3b.2
    Other_sequence (37)
    Associated_feature: WBsf644354
      WBsf988367
      WBsf221563
  Experimental_info: RNAi_result: WBRNAi00090580 Inferred_automatically: RNAi_primary
      WBRNAi00011275 Inferred_automatically: RNAi_primary
      WBRNAi00083277 Inferred_automatically: RNAi_primary
      WBRNAi00076171 Inferred_automatically: RNAi_primary
      WBRNAi00041374 Inferred_automatically: RNAi_primary
    Expr_pattern (11)
    Drives_construct: WBCnstr00002407
      WBCnstr00028273
      WBCnstr00042661
      WBCnstr00042662
      WBCnstr00042663
    Construct_product: WBCnstr00028273
      WBCnstr00042661
      WBCnstr00042662
      WBCnstr00042663
    Regulate_expr_cluster: WBPaper00066004:fust-1(csb21)_downregulated
      WBPaper00066004:fust-1(csb21)_upregulated
    Microarray_results (19)
    Expression_cluster (109)
    Interaction (197)
  Map_info: Map: II Position: 0.496031 Error: 0.000218
    Positive: Positive_clone: C27H5 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00039140
    WBPaper00043234
    WBPaper00046432
    WBPaper00052702
    WBPaper00053121
    WBPaper00053757
    WBPaper00055090
    WBPaper00058116
    WBPaper00062110
    WBPaper00063415
    WBPaper00063450
    WBPaper00064663
    WBPaper00066004
    WBPaper00066342
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene