WormBase Tree Display for Gene: WBGene00001831
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WBGene00001831 | SMap | S_parent | Sequence | F58A4 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | hcp | ||||||
Allele (12) | |||||||
Strain | WBStrain00036564 | ||||||
WBStrain00034729 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (35) | |||||||
Ortholog (36) | |||||||
Paralog (24) | |||||||
Structured_description | Concise_description | The hcp-3 gene encodes a centromere protein (CENP)-A homolog required for kinetochore function; inactivation of hcp-3 in one-cell embryos by RNAi causes a complete loss of kinetochores, with total failure of chromosomes to segregate properly during mitosis, to recruit components to the kinetochore other than HCP-3, or to assemble a stable mitotic spindle; in addition, HCP-4 fails to localize properly to the kinetochore in hcp-3(RNAi) embryos. | Paper_evidence | WBPaper00003702 | |||
WBPaper00004736 | |||||||
Curator_confirmed | WBPerson567 | ||||||
Date_last_updated | 16 Dec 2005 00:00:00 | ||||||
Automated_description | Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in several processes, including negative regulation of mitotic centrosome separation; non-membrane-bounded organelle assembly; and protein localization to chromosome. Located in kinetochore and nucleus. Expressed in embryonic cell; hyp3; hyp4; hyp7 syncytium; and seam cell. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F58A4.3 | |||||
Corresponding_transcript | F58A4.3.1 | ||||||
Other_sequence | CBC08194 | ||||||
Associated_feature | WBsf651390 | ||||||
WBsf993732 | |||||||
WBsf227335 | |||||||
Experimental_info | RNAi_result (32) | ||||||
Expr_pattern (11) | |||||||
Drives_construct | WBCnstr00014536 | ||||||
WBCnstr00022767 | |||||||
WBCnstr00022768 | |||||||
WBCnstr00036660 | |||||||
Construct_product | WBCnstr00014534 | ||||||
WBCnstr00014535 | |||||||
WBCnstr00014536 | |||||||
WBCnstr00022767 | |||||||
WBCnstr00036660 | |||||||
Antibody | WBAntibody00000241 | ||||||
WBAntibody00000379 | |||||||
WBAntibody00000811 | |||||||
WBAntibody00000812 | |||||||
WBAntibody00001030 | |||||||
WBAntibody00002323 | |||||||
WBAntibody00002956 | |||||||
Microarray_results | SMD_F58A4.3 | ||||||
190809_s_at | |||||||
A_12_P101206 | |||||||
Aff_F58A4.3 | |||||||
GPL13394_WBGene00001831 | |||||||
GPL13914_F58A4.3 | |||||||
GPL14144_F58A4.3_740-799_0.934_5_A | |||||||
GPL14144_F58A4.3_794-853_0.934_6_B | |||||||
GPL19516_CGZ0025119 | |||||||
GPL21109_F58A4.3 | |||||||
GPL3518_CE00219 | |||||||
GPL8304_CE_WBGene00001831_A | |||||||
GPL8673_F58A4_3P00192 | |||||||
GPL8673_F58A4_3P00453 | |||||||
GPL8673_F58A4_3P00764 | |||||||
GPL9450_F58A4.3 | |||||||
cea2.p.66670 | |||||||
Expression_cluster (172) | |||||||
Interaction (233) | |||||||
Map_info | Map | III | Position | 0.752765 | Error | 0.006625 | |
Positive | Positive_clone | F58A4 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Pseudo_map_position | |||||||
Reference (42) | |||||||
Remark | Sequence connection from [Moore LL, Roth MB]. krb 13/11/01 | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |