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WormBase Tree Display for Gene: WBGene00000786

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Name Class

WBGene00000786SMapS_parentSequenceC25B8
IdentityVersion1
Name (5)
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcpr
Allele (38)
Legacy_information[C.elegansII] pk91 : Tc1 insertion, no known phenotype. Encodes protein with significant similarity to proteases of Cathepsin B family (EST cm01a5). [IA]
RNASeq_FPKM (74)
GO_annotation00046005
00046006
00046007
00046008
00046009
00046010
00046011
00046012
00107792
00107793
Ortholog (35)
Paralog (28)
Structured_descriptionAutomated_descriptionPredicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Located in lysosome. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9351Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:11054Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:2671Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:9352Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:2377Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:10941Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:12842Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:3068Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:4914Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
DOID:1612Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2527)
Molecular_infoCorresponding_CDSC25B8.3
Corresponding_CDS_historyC25B8.3b:wp271
C25B8.3c:wp271
Corresponding_transcriptC25B8.3.1
Other_sequence (548)
Associated_featureWBsf648237
WBsf235856
Experimental_infoRNAi_resultWBRNAi00027664Inferred_automaticallyRNAi_primary
WBRNAi00076158Inferred_automaticallyRNAi_primary
WBRNAi00088992Inferred_automaticallyRNAi_primary
WBRNAi00115173Inferred_automaticallyRNAi_primary
WBRNAi00041163Inferred_automaticallyRNAi_primary
WBRNAi00086767Inferred_automaticallyRNAi_primary
WBRNAi00093243Inferred_automaticallyRNAi_primary
WBRNAi00011146Inferred_automaticallyRNAi_primary
Expr_patternExpr743
Expr1015929
Expr1030487
Expr1145192
Expr2010507
Expr2028747
Drives_constructWBCnstr00007422
WBCnstr00037276
Construct_productWBCnstr00007564
WBCnstr00037276
Microarray_resultsSMD_C25B8.3
180122_at
A_12_P107462
A_12_P119120
A_12_P151585
A_12_P169772
A_12_P169773
A_12_P169774
A_12_P169775
A_12_P169776
Aff_C25B8.3
GPL13394_WBGene00000786
GPL13914_C25B8.3
GPL14144_C25B8.3a_1062-1121_0.954_1_A
GPL14144_C25B8.3a_350-409_0.905_8_C
GPL14144_C25B8.3a_671-730_0.920_6_B
GPL19516_CGZ0005858
GPL19516_CGZ0005859
GPL19516_CGZ0005860
GPL21109_C25B8.3a
GPL3518_CE04078
GPL8304_CE_WBGene00000786_A
GPL8304_CE_WBGene00000786_B
GPL8673_C25B8_3aP00010
GPL8673_C25B8_3aP00508
GPL8673_C25B8_3aP00978
GPL8673_C25B8_3bP00007
GPL8673_C25B8_3bP00505
GPL8673_C25B8_3bP00975
GPL9450_C25B8.3a
GPL9450_C25B8.3b
cea2.d.07778
cea2.d.14216
Expression_cluster (248)
Interaction (108)
Map_infoMapXPosition-2.73949Error0.013617
PositivePositive_cloneC25B8Author_evidenceLarminie CGC
Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4237
Pseudo_map_position
Reference (11)
Remarkdata received 11/94
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene