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WormBase Tree Display for Gene: WBGene00000182

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Name Class

WBGene00000182SMapS_parentSequenceB0336
IdentityVersion3
NameCGC_namearf-1
Sequence_nameB0336.2
Molecular_nameB0336.2
B0336.2.1
CE00696
B0336.2.2
Other_nameARF/1
arf-1.2
CELE_B0336.2Accession_evidenceNDBBX284603
Public_namearf-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
205 Nov 2004 15:32:14WBPerson2970Name_changeCGC_namearf-1.2
310 Sep 2020 13:24:17WBPerson1983Name_changeCGC_namearf-1
Other_namearf-1.2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classarf
Allele (33)
Legacy_information[C.elegansII] NMK. Encodes 181 aa predicted class I ARF. [CGC, MQ]
RNASeq_FPKM (74)
GO_annotation (22)
Contained_in_operonCEOP3332
Ortholog (45)
Paralog (14)
Structured_descriptionConcise_descriptionarf-1.2 encodes an ADP-ribosylation factor homolog required in vivo for embryonic development, fertility, locomotion, vulval development, and cuticular synthesis; ARF proteins are N-myristoylated GTPases that regulate membrane traffic and the actin cytoskeleton, and that activate both phospholipase D1 (PLD1) and phosphatidylinositol 4-phosphate 5-kinase.Paper_evidenceWBPaper00012958
WBPaper00013160
WBPaper00015195
Curator_confirmedWBPerson567
Date_last_updated16 Jul 2007 00:00:00
Automated_descriptionPredicted to enable GTP binding activity and GTPase activity. Involved in several processes, including oocyte development; regulation of apoptotic process involved in development; and regulation of receptor-mediated endocytosis. Located in endoplasmic reticulum. Expressed in pharyngeal muscle cell; uterus; ventral nerve cord; and vulval precursor cell. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Is an ortholog of human ARF1 (ADP ribosylation factor 1) and ARF3 (ADP ribosylation factor 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0050454Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:652)
Molecular_infoCorresponding_CDSB0336.2
Corresponding_transcriptB0336.2.1
B0336.2.2
Other_sequence (178)
Associated_feature (13)
Experimental_infoRNAi_result (38)
Expr_patternChronogram1686
Expr3149
Expr4834
Expr5055
Expr15679
Expr1028066
Expr1030106
Expr1143124
Expr2009391
Expr2027627
Drives_constructWBCnstr00002999
WBCnstr00011177
WBCnstr00012265
WBCnstr00019869
WBCnstr00037680
WBCnstr00042476
Construct_productWBCnstr00008785
WBCnstr00008786
WBCnstr00019869
WBCnstr00037680
WBCnstr00042476
Microarray_resultsSMD_B0336.2
174943_at
174944_s_at
187865_at
A_12_P111585
A_12_P145025
A_12_P145026
A_12_P145027
Aff_B0336.2
GPL13394_WBGene00000182
GPL13914_B0336.2
GPL14144_B0336.2_375-434_0.902_3_B
GPL14144_B0336.2_496-555_0.949_1_A
GPL14144_B0336.2_87-146_0.902_2_C
GPL19516_CGZ0000790
GPL19516_CGZ0000791
GPL21109_B0336.2.1
GPL21109_B0336.2.2
GPL3518_CE00696
GPL8304_CE_WBGene00000182_A
GPL8304_CE_WBGene00000182_B
GPL8673_B0336_2P00031
GPL8673_B0336_2P00380
GPL8673_B0336_2P00416
GPL9450_B0336.2
cea2.c.16218
Expression_cluster (132)
Interaction (182)
Map_infoMapIIIPosition-1.44726Error0.000356
PositivePositive_cloneB0336Inferred_automaticallyFrom sequence, transcript, pseudogene data
NM#G4
Mapping_dataMulti_point4788
5049
Pseudo_map_position
ReferenceWBPaper00003831
WBPaper00004211
WBPaper00004403
WBPaper00006425
WBPaper00015195
WBPaper00024200
WBPaper00025163
WBPaper00027296
WBPaper00027612
WBPaper00028050
WBPaper00030963
WBPaper00031019
WBPaper00031224
WBPaper00032446
WBPaper00033606
WBPaper00038432
WBPaper00038491
WBPaper00040857
WBPaper00041831
WBPaper00045696
WBPaper00045882
WBPaper00047716
WBPaper00047992
WBPaper00048305
WBPaper00048321
WBPaper00049828
WBPaper00050606
WBPaper00052225
WBPaper00054370
WBPaper00055090
WBPaper00061547
WBPaper00061805
WBPaper00062255
WBPaper00062289
WBPaper00063177
WBPaper00064057
WBPaper00066233
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
This gene was previously assigned the CGC name arf-1. It has been re-assigned to arf-1.2Curator_confirmedWBPerson2970
MethodGene