WormBase Tree Display for Gene: WBGene00045383
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| WBGene00045383 | SMap | S_parent | Sequence | C25A1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | sup-46 | Paper_evidence | WBPaper00028588 | |||||
| Person_evidence | WBPerson261 | ||||||||
| Sequence_name | C25A1.4 | ||||||||
| Molecular_name | C25A1.4 | ||||||||
| C25A1.4.1 | |||||||||
| CE08369 | |||||||||
| Other_name | CELE_C25A1.4 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | sup-46 | ||||||||
| DB_info | Database | NDB | locus_tag | CELE_C25A1.4 | |||||
| Panther | gene | CAEEL|WormBase=WBGene00045383|UniProtKB=Q9XVS2 | |||||||
| family | PTHR23003 | ||||||||
| NCBI | gene | 172881 | |||||||
| RefSeq | protein | NM_060276.6 | |||||||
| TREEFAM | TREEFAM_ID | TF313406 | |||||||
| TrEMBL | UniProtAcc | Q9XVS2 | |||||||
| UniProt_GCRP | UniProtAcc | Q9XVS2 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 12 Apr 2007 13:43:01 | WBPerson2970 | Event | Created | |||
| 2 | 01 Aug 2017 12:21:15 | WBPerson2970 | Event | Acquires_merge | WBGene00007706 | ||||
| Name_change | Sequence_name | C25A1.4 | |||||||
| Acquires_merge | WBGene00007706 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sup | ||||||||
| Allele (35) | |||||||||
| Strain | WBStrain00040607 | ||||||||
| WBStrain00040604 | |||||||||
| WBStrain00040606 | |||||||||
| WBStrain00005633 | |||||||||
| WBStrain00005630 | |||||||||
| WBStrain00051098 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Ortholog (43) | |||||||||
| Structured_description | Concise_description | sup-46, when mutated, suppresses the lethality of gna-2(qa705); however, the three suppressor alleles (qa707, qa708, qa709) require a gna-1(+) background for suppression, suggesting that uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) synthesis is indispensable for embryonic development, and that SUP-46 normally inhibits GNA-1 in tissues where GNA-2 is normally active. | Paper_evidence | WBPaper00028588 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 20 Jul 2017 00:00:00 | ||||||||
| Automated_description | Predicted to enable mRNA binding activity. Predicted to be located in cytoplasm and nucleus. Expressed in germ cell and somatic cell. Human ortholog(s) of this gene implicated in colorectal carcinoma and leiomyoma. Is an ortholog of human HNRNPM (heterogeneous nuclear ribonucleoprotein M) and MYEF2 (myelin expression factor 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:127 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5046) | ||||
| DOID:0080199 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5046) | ||||||
| Molecular_info (4) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00082502 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00082575 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061737 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00102167 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00029172 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116904 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00041144 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003012 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr15106 | ||||||||
| Expr1020053 | |||||||||
| Expr1033335 | |||||||||
| Expr1145177 | |||||||||
| Expr2001062 | |||||||||
| Expr2019281 | |||||||||
| Drives_construct | WBCnstr00033542 | ||||||||
| Construct_product | WBCnstr00033542 | ||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (123) | |||||||||
| Interaction | WBInteraction000050763 | ||||||||
| WBInteraction000505776 | |||||||||
| WBInteraction000505777 | |||||||||
| WBInteraction000509968 | |||||||||
| WBInteraction000509971 | |||||||||
| WBInteraction000509972 | |||||||||
| WBInteraction000509977 | |||||||||
| WBInteraction000509978 | |||||||||
| WBInteraction000509983 | |||||||||
| WBInteraction000509987 | |||||||||
| WBInteraction000509990 | |||||||||
| WBInteraction000509991 | |||||||||
| WBInteraction000509992 | |||||||||
| WBInteraction000516037 | |||||||||
| WBInteraction000516042 | |||||||||
| WBInteraction000543366 | |||||||||
| WBInteraction000547335 | |||||||||
| WBInteraction000547355 | |||||||||
| WBInteraction000547356 | |||||||||
| WBInteraction000547357 | |||||||||
| WBInteraction000547358 | |||||||||
| WBInteraction000547359 | |||||||||
| WBInteraction000547360 | |||||||||
| WBInteraction000547361 | |||||||||
| WBInteraction000547362 | |||||||||
| WBInteraction000547363 | |||||||||
| WBInteraction000547364 | |||||||||
| WBInteraction000552124 | |||||||||
| WBInteraction000553310 | |||||||||
| WBInteraction000557825 | |||||||||
| WBInteraction000559083 | |||||||||
| WBInteraction000560617 | |||||||||
| WBInteraction000564793 | |||||||||
| WBInteraction000564903 | |||||||||
| WBInteraction000569739 | |||||||||
| WBInteraction000570088 | |||||||||
| WBInteraction000574799 | |||||||||
| WBInteraction000583574 | |||||||||
| Map_info | Map | I | Position | 4.71731 | |||||
| Positive | Positive_clone | C25A1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00051515 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00064339 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
