WormBase Tree Display for Gene: WBGene00022599

WBGene00022599 SMap: S_parent: Sequence: ZC395
  Identity: Version: 2
    Name: CGC_name: daf-41 Paper_evidence: WBPaper00046600
          Person_evidence: WBPerson759
      Sequence_name: ZC395.10
      Molecular_name: ZC395.10
        ZC395.10.1
        CE01436
      Other_name: CELE_ZC395.10 Accession_evidence: NDB BX284603
      Public_name: daf-41
    DB_info: Database: AceView gene 3G364
        WormQTL gene WBGene00022599
        WormFlux gene WBGene00022599
        NDB locus_tag CELE_ZC395.10
        Panther gene CAEEL|WormBase=WBGene00022599|UniProtKB=Q23280
          family PTHR22932
        NCBI gene 175727
        RefSeq protein NM_065725.5
        SwissProt UniProtAcc Q23280
        TREEFAM TREEFAM_ID TF315077
        UniProt_GCRP UniProtAcc Q23280
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:06 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 21 Sep 2017 11:27:19 WBPerson2970 Name_change: CGC_name: daf-41
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: daf
    Allele (15)
    Strain: WBStrain00001518
      WBStrain00032911
      WBStrain00032936
      WBStrain00037205
    RNASeq_FPKM (74)
    GO_annotation: 00077908
      00077909
      00077910
      00077911
      00077912
      00077913
      00077914
      00126638
    Contained_in_operon: CEOP3276
    Ortholog (42)
    Structured_description: Automated_description: Predicted to enable Hsp90 protein binding activity and protein-folding chaperone binding activity. Predicted to be involved in chaperone-mediated protein complex assembly and protein folding. Located in myofibril. Expressed in several structures, including amphid neurons; anal depressor muscle; phasmid neurons; touch receptor neurons; and vulva. Human ortholog(s) of this gene implicated in atherosclerosis; breast cancer; and oligodendroglioma. Is an ortholog of human PTGES3 (prostaglandin E synthase 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:3181 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:16049)
      DOID:1936 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:16049)
      DOID:1612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:16049)
  Molecular_info (4)
  Experimental_info: RNAi_result (12)
    Expr_pattern (12)
    Drives_construct: WBCnstr00002375
      WBCnstr00004326
      WBCnstr00024122
    Construct_product: WBCnstr00013931
      WBCnstr00024122
      WBCnstr00040348
    Microarray_results (20)
    Expression_cluster (160)
    Interaction: WBInteraction000006378
      WBInteraction000105076
      WBInteraction000110410
      WBInteraction000114901
      WBInteraction000127098
      WBInteraction000139345
      WBInteraction000142710
      WBInteraction000144030
      WBInteraction000145052
      WBInteraction000147748
      WBInteraction000148558
      WBInteraction000150517
      WBInteraction000151972
      WBInteraction000156888
      WBInteraction000158356
      WBInteraction000161160
      WBInteraction000165093
      WBInteraction000169053
      WBInteraction000169408
      WBInteraction000170046
      WBInteraction000170491
      WBInteraction000172864
      WBInteraction000174273
      WBInteraction000174318
      WBInteraction000175874
      WBInteraction000178265
      WBInteraction000178266
      WBInteraction000180916
      WBInteraction000181146
      WBInteraction000182516
      WBInteraction000183851
      WBInteraction000186151
      WBInteraction000189589
      WBInteraction000196120
      WBInteraction000205034
      WBInteraction000207408
      WBInteraction000207777
      WBInteraction000209570
      WBInteraction000213985
      WBInteraction000215374
      WBInteraction000215849
      WBInteraction000217230
      WBInteraction000223714
      WBInteraction000224534
      WBInteraction000225754
      WBInteraction000226275
      WBInteraction000239474
      WBInteraction000239475
      WBInteraction000239517
      WBInteraction000240044
      WBInteraction000244584
      WBInteraction000247175
      WBInteraction000247890
      WBInteraction000250262
      WBInteraction000253797
      WBInteraction000262175
      WBInteraction000262316
      WBInteraction000264184
      WBInteraction000265376
      WBInteraction000273604
      WBInteraction000275998
      WBInteraction000280537
      WBInteraction000283781
      WBInteraction000294651
      WBInteraction000296265
      WBInteraction000296358
      WBInteraction000298100
      WBInteraction000299904
      WBInteraction000302393
      WBInteraction000306967
      WBInteraction000307165
      WBInteraction000309372
      WBInteraction000323037
      WBInteraction000328027
      WBInteraction000328640
      WBInteraction000331928
      WBInteraction000332922
      WBInteraction000336507
      WBInteraction000337695
      WBInteraction000337943
      WBInteraction000341355
      WBInteraction000342788
      WBInteraction000343401
      WBInteraction000347742
      WBInteraction000364225
      WBInteraction000368942
      WBInteraction000370521
      WBInteraction000370819
      WBInteraction000375738
      WBInteraction000375739
      WBInteraction000376942
      WBInteraction000392567
      WBInteraction000392906
      WBInteraction000393834
      WBInteraction000398888
      WBInteraction000405641
      WBInteraction000405788
      WBInteraction000409965
      WBInteraction000413641
      WBInteraction000414726
      WBInteraction000421051
      WBInteraction000423613
      WBInteraction000429158
      WBInteraction000429568
      WBInteraction000431021
      WBInteraction000431320
      WBInteraction000439561
      WBInteraction000441482
      WBInteraction000444659
      WBInteraction000445583
      WBInteraction000447219
      WBInteraction000447855
      WBInteraction000448112
      WBInteraction000452382
      WBInteraction000455330
      WBInteraction000456263
      WBInteraction000460326
      WBInteraction000464029
      WBInteraction000464136
      WBInteraction000464381
      WBInteraction000464417
      WBInteraction000464898
      WBInteraction000464899
      WBInteraction000465544
      WBInteraction000467628
      WBInteraction000467858
      WBInteraction000470103
      WBInteraction000470590
      WBInteraction000470981
      WBInteraction000472475
      WBInteraction000473455
      WBInteraction000474369
      WBInteraction000474813
      WBInteraction000525196
      WBInteraction000525197
      WBInteraction000525198
      WBInteraction000525199
      WBInteraction000525200
      WBInteraction000525201
      WBInteraction000525202
      WBInteraction000525203
      WBInteraction000525204
      WBInteraction000525205
      WBInteraction000525206
      WBInteraction000525207
      WBInteraction000534897
      WBInteraction000550116
      WBInteraction000551399
      WBInteraction000554749
      WBInteraction000557924
      WBInteraction000569183
      WBInteraction000569536
      WBInteraction000570896
      WBInteraction000571089
      WBInteraction000571121
      WBInteraction000571692
      WBInteraction000578214
      WBInteraction000581286
      WBInteraction000582413
      WBInteraction000584981
  Map_info: Map: III Position: -1.84928
    Positive: Positive_clone: ZC395 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (16)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene