Enables 6-pyruvoyltetrahydropterin synthase activity and identical protein binding activity. Involved in tetrahydrobiopterin biosynthetic process. Predicted to be located in mitochondrion. Expressed in hypodermis and neurons. Human ortholog(s) of this gene implicated in BH4-deficient hyperphenylalaninemia A and phenylketonuria. Is an ortholog of human PTS (6-pyruvoyltetrahydropterin synthase).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.