WormBase Tree Display for Gene: WBGene00009004

WBGene00009004 SMap: S_parent: Sequence: F21C3
  Identity: Version: 2
    Name: CGC_name: pfd-6 Person_evidence: WBPerson3663
            WBPerson2136
      Sequence_name: F21C3.5
      Molecular_name: F21C3.5
        F21C3.5.1
        CE05680
      Other_name: CELE_F21C3.5 Accession_evidence: NDB BX284601
      Public_name: pfd-6
    DB_info: Database: AceView gene 1H860
        WormQTL gene WBGene00009004
        WormFlux gene WBGene00009004
        NDB locus_tag CELE_F21C3.5
        Panther gene CAEEL|WormBase=WBGene00009004|UniProtKB=P52554
          family PTHR21431
        NCBI gene 172474
        RefSeq protein NM_059657.6
        SwissProt UniProtAcc P52554
        TREEFAM TREEFAM_ID TF315166
        UniProt_GCRP UniProtAcc P52554
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 02 Aug 2006 11:39:27 WBPerson2970 Name_change: CGC_name: pfd-6
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pfd
    Allele (15)
    Strain: WBStrain00027642
      WBStrain00037185
      WBStrain00037512
    RNASeq_FPKM (74)
    GO_annotation (11)
    Contained_in_operon: CEOP1384
    Ortholog (35)
    Structured_description: Concise_description: pfd-6 encodes a putative prefoldin 6 subunit, orthologous to human PFDN6 (OMIM:605660), required for normal microtubule growth and distal tip cell migration; PFD-6 is expressed cytoplasmically in most, if not all, tissues, including the germline; in mass RNAi assays, PFD-6 is required for normal mitotic spindle position, embryonic and larval viability, fertility, body shape, vulval development, and locomotion, and for normally rapid growth; pfd-6(RNAi) embryos show a reduced microtubule growth rate. Paper_evidence (7)
          Curator_confirmed: WBPerson567
          Date_last_updated: 14 Jan 2008 00:00:00
      Automated_description: Predicted to enable protein-folding chaperone binding activity. Predicted to be involved in chaperone-mediated protein complex assembly and protein folding. Located in cytoplasm. Expressed in body wall musculature; hypodermal cell; intestinal cell; and non-striated muscle. Is an ortholog of human PFDN6 (prefoldin subunit 6). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F21C3.5
    Corresponding_transcript: F21C3.5.1
    Other_sequence (31)
    Associated_feature: WBsf649304
      WBsf664429
      WBsf219731
      WBsf219732
  Experimental_info: RNAi_result (11)
    Expr_pattern: Expr7841
      Expr14586
      Expr1020376
      Expr1033920
      Expr1149123
      Expr2014846
      Expr2033081
    Drives_construct: WBCnstr00001361
      WBCnstr00032533
      WBCnstr00041173
    Construct_product: WBCnstr00032533
      WBCnstr00041173
    Regulate_expr_cluster: WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055827:pfd-6(gk493446)_upregulated
    Antibody: WBAntibody00001342
    Microarray_results (18)
    Expression_cluster (133)
    Interaction: WBInteraction000029137
      WBInteraction000034832
      WBInteraction000035562
      WBInteraction000035752
      WBInteraction000036541
      WBInteraction000037079
      WBInteraction000037626
      WBInteraction000038791
      WBInteraction000038898
      WBInteraction000038899
      WBInteraction000038977
      WBInteraction000039597
      WBInteraction000039803
      WBInteraction000040341
      WBInteraction000041219
      WBInteraction000042051
      WBInteraction000043310
      WBInteraction000043531
      WBInteraction000045493
      WBInteraction000045494
      WBInteraction000045625
      WBInteraction000045627
      WBInteraction000045628
      WBInteraction000045979
      WBInteraction000045980
      WBInteraction000046693
      WBInteraction000047847
      WBInteraction000047849
      WBInteraction000047851
      WBInteraction000047853
      WBInteraction000048538
      WBInteraction000050388
      WBInteraction000050389
      WBInteraction000052476
      WBInteraction000101974
      WBInteraction000101992
      WBInteraction000121172
      WBInteraction000123174
      WBInteraction000123175
      WBInteraction000124022
      WBInteraction000134620
      WBInteraction000147168
      WBInteraction000149475
      WBInteraction000174090
      WBInteraction000174225
      WBInteraction000174226
      WBInteraction000174227
      WBInteraction000174228
      WBInteraction000183392
      WBInteraction000193061
      WBInteraction000193733
      WBInteraction000201854
      WBInteraction000201949
      WBInteraction000203572
      WBInteraction000215114
      WBInteraction000242209
      WBInteraction000244430
      WBInteraction000248739
      WBInteraction000253624
      WBInteraction000253754
      WBInteraction000293569
      WBInteraction000296552
      WBInteraction000308537
      WBInteraction000312944
      WBInteraction000313117
      WBInteraction000314411
      WBInteraction000330550
      WBInteraction000331411
      WBInteraction000331527
      WBInteraction000331528
      WBInteraction000331529
      WBInteraction000331530
      WBInteraction000336749
      WBInteraction000358151
      WBInteraction000366093
      WBInteraction000372868
      WBInteraction000378630
      WBInteraction000378643
      WBInteraction000382101
      WBInteraction000395426
      WBInteraction000396897
      WBInteraction000396898
      WBInteraction000396899
      WBInteraction000396900
      WBInteraction000396901
      WBInteraction000397491
      WBInteraction000398107
      WBInteraction000400338
      WBInteraction000401741
      WBInteraction000406296
      WBInteraction000414284
      WBInteraction000424253
      WBInteraction000435449
      WBInteraction000442536
      WBInteraction000443904
      WBInteraction000445415
      WBInteraction000453934
      WBInteraction000459391
      WBInteraction000460617
      WBInteraction000461938
      WBInteraction000462548
      WBInteraction000462549
      WBInteraction000463572
      WBInteraction000465144
      WBInteraction000465145
      WBInteraction000465146
      WBInteraction000465147
      WBInteraction000465148
      WBInteraction000467112
      WBInteraction000467113
      WBInteraction000467114
      WBInteraction000468177
      WBInteraction000468178
      WBInteraction000468769
      WBInteraction000468781
      WBInteraction000470784
      WBInteraction000471603
      WBInteraction000471983
      WBInteraction000472205
      WBInteraction000472743
      WBInteraction000473133
      WBInteraction000473244
      WBInteraction000473554
      WBInteraction000474643
      WBInteraction000475112
      WBInteraction000523298
      WBInteraction000541853
      WBInteraction000554169
      WBInteraction000559788
      WBInteraction000559789
      WBInteraction000559790
      WBInteraction000559791
      WBInteraction000559792
      WBInteraction000559793
      WBInteraction000559794
      WBInteraction000559795
      WBInteraction000559796
      WBInteraction000559797
      WBInteraction000559798
      WBInteraction000559799
      WBInteraction000559800
      WBInteraction000559879
      WBInteraction000561496
      WBInteraction000562819
      WBInteraction000562820
      WBInteraction000562821
      WBInteraction000565016
      WBInteraction000565738
      WBInteraction000568735
      WBInteraction000575776
      WBInteraction000577868
      WBInteraction000580628
  Map_info: Map: I Position: 1.87364 Error: 0.000337
    Positive: Positive_clone: F21C3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00031309
    WBPaper00038491
    WBPaper00051688
    WBPaper00055090
    WBPaper00055827
    WBPaper00057394
    WBPaper00064339
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene