WormBase Tree Display for Gene: WBGene00008149

WBGene00008149 SMap: S_parent: Sequence: C47E12
  Identity: Version: 2
    Name (5)
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:48 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 09 Sep 2005 11:08:45 WBPerson2970 Name_change: CGC_name: pyp-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pyp
    Allele (38)
    Strain: WBStrain00027494
    RNASeq_FPKM (74)
    GO_annotation (16)
    Contained_in_operon: CEOP4348
    Ortholog (49)
    Structured_description: Concise_description: pyp-1 encodes, by alternative splicing, three isoforms of an inorganic pyrophosphatase required for embryonic and larval viability, intestinal function, and distal tip cell migration; PYP-1 is catalytically active in vitro, and is expressed in neurons, intestine, and coelomocytes; PYP-1 is orthologous to Drosophila NURF-38, and to human PPA1 (OMIM:179030) and PPA2; by orthology with NURF-38, PYP-1 is also predicted to participate in nucleosome remodelling. Paper_evidence: WBPaper00027681
            WBPaper00028783
            WBPaper00031169
            WBPaper00031236
          Curator_confirmed: WBPerson567
          Date_last_updated: 26 Nov 2007 00:00:00
      Automated_description: Predicted to enable inorganic diphosphate phosphatase activity. Involved in innate immune response. Located in neuron projection and vacuole. Expressed in coelomocyte and neurons. Is an ortholog of human PPA1 (inorganic pyrophosphatase 1) and PPA2 (inorganic pyrophosphatase 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C47E12.4a
      C47E12.4c
      C47E12.4d
    Corresponding_CDS_history: C47E12.4:wp99
      C47E12.4b:wp236
      C47E12.4b:wp261
      C47E12.4c:wp236
    Corresponding_transcript: C47E12.4a.1
      C47E12.4c.1
      C47E12.4d.1
    Other_sequence (133)
    Associated_feature (11)
  Experimental_info: RNAi_result (19)
    Expr_pattern: Expr7807
      Expr1020480
      Expr1033540
      Expr1146667
      Expr2015205
      Expr2033439
    Drives_construct: WBCnstr00012939
      WBCnstr00033204
    Construct_product: WBCnstr00012939
      WBCnstr00033204
    Antibody: WBAntibody00001321
    Microarray_results (41)
    Expression_cluster (145)
    Interaction: WBInteraction000035363
      WBInteraction000035776
      WBInteraction000037370
      WBInteraction000038642
      WBInteraction000041603
      WBInteraction000041626
      WBInteraction000043630
      WBInteraction000043632
      WBInteraction000043714
      WBInteraction000043789
      WBInteraction000044019
      WBInteraction000044161
      WBInteraction000046750
      WBInteraction000046751
      WBInteraction000047002
      WBInteraction000047975
      WBInteraction000048547
      WBInteraction000050224
      WBInteraction000050254
      WBInteraction000050267
      WBInteraction000050292
      WBInteraction000050299
      WBInteraction000050300
      WBInteraction000050302
      WBInteraction000050305
      WBInteraction000050333
      WBInteraction000050341
      WBInteraction000050342
      WBInteraction000134913
      WBInteraction000155240
      WBInteraction000155274
      WBInteraction000155275
      WBInteraction000155276
      WBInteraction000155277
      WBInteraction000155278
      WBInteraction000155279
      WBInteraction000155280
      WBInteraction000185396
      WBInteraction000222620
      WBInteraction000229344
      WBInteraction000254640
      WBInteraction000277329
      WBInteraction000294646
      WBInteraction000313573
      WBInteraction000319152
      WBInteraction000343105
      WBInteraction000353101
      WBInteraction000356579
      WBInteraction000373471
      WBInteraction000377197
      WBInteraction000397926
      WBInteraction000417168
      WBInteraction000422872
      WBInteraction000453271
      WBInteraction000464728
      WBInteraction000465012
      WBInteraction000465308
      WBInteraction000467498
      WBInteraction000470064
      WBInteraction000470065
      WBInteraction000471451
      WBInteraction000471823
      WBInteraction000473947
      WBInteraction000474455
      WBInteraction000519958
      WBInteraction000539381
      WBInteraction000542058
      WBInteraction000542118
      WBInteraction000542129
      WBInteraction000542134
      WBInteraction000542579
      WBInteraction000542585
      WBInteraction000542793
      WBInteraction000551801
      WBInteraction000562013
      WBInteraction000563178
      WBInteraction000564174
      WBInteraction000571891
      WBInteraction000577850
      WBInteraction000580579
      WBInteraction000583187
  Map_info: Map: IV Position: 4.46234 Error: 0.00085
    Positive: Positive_clone: C47E12 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (17)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene