WormBase Tree Display for Gene: WBGene00004988

WBGene00004988 SMap: S_parent: Sequence: T08A9
  Identity: Version: 1
    Name: CGC_name: spp-3
      Sequence_name: T08A9.7
      Molecular_name: T08A9.7
        T08A9.7.1
        CE31233
      Other_name: CELE_T08A9.7 Accession_evidence: NDB BX284606
      Public_name: spp-3
    DB_info: Database: AceView gene XH934
        WormQTL gene WBGene00004988
        WormFlux gene WBGene00004988
        NDB locus_tag CELE_T08A9.7
        Panther gene CAEEL|WormBase=WBGene00004988|UniProtKB=Q22336
          family PTHR21579
        NCBI gene 180993
        RefSeq protein NM_076834.8
        TREEFAM TREEFAM_ID TF343148
        TrEMBL UniProtAcc Q22336
        UniProt_GCRP UniProtAcc Q22336
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:37 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: spp
    Allele (14)
    RNASeq_FPKM (74)
    GO_annotation: 00071188
      00071189
      00071190
      00071191
      00071192
    Ortholog (26)
    Paralog (12)
    Structured_description: Concise_description: spp-3 encodes an antimicrobial peptide that belongs to the SPP-protein family, called caenopores, with structural similarity to saposin-like proteins (SAPLIPs), the amoebapores and the mammalian NK-lysin and granulysin; caenopores are part of the worm's innate immune system and interact with and eliminate bacteria via membrane pore-forming activity; C. elegans has at least 33 putative SPP proteins; in an heterologous expression system, spp-3 formed pores in liposomes, and showed antimicrobial activity against several gram- negative and positive bacteria such as E. coli, P. aeruginosa, Ph. luminescence, X. nematophila, Y. enterocolitica, B. megaterium and B. thuringiensis; spp-3 is expressed in the intestine and the SDQR head neuron. Paper_evidence: WBPaper00041167
            WBPaper00035289
          Curator_confirmed: WBPerson324
          Date_last_updated: 17 Sep 2013 00:00:00
      Automated_description: Enables identical protein binding activity. Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Located in protein-containing complex. Expressed in SDQR. Paper_evidence: WBPaper00065943
          Curator_confirmed (2)
          Inferred_automatically: This description was generated automatically by a script based on data from the WS292 version of WormBase
          Date_last_updated: 24 Apr 2024 00:00:00
  Molecular_info: Corresponding_CDS: T08A9.7
    Corresponding_transcript: T08A9.7.1
    Other_sequence: CRC07887_1
      CBC05377_1
      CR08323
      CJC04748_1
    Associated_feature (9)
  Experimental_info: RNAi_result: WBRNAi00082192 Inferred_automatically: RNAi_primary
      WBRNAi00052828 Inferred_automatically: RNAi_primary
      WBRNAi00092241 Inferred_automatically: RNAi_primary
      WBRNAi00082199 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr10056
      Expr1028065
      Expr1156430
      Expr2016081
      Expr2034317
    Drives_construct: WBCnstr00015028
      WBCnstr00035289
    Construct_product: WBCnstr00015028
      WBCnstr00035289
    Microarray_results (17)
    Expression_cluster (213)
    Interaction: WBInteraction000134106
      WBInteraction000134111
      WBInteraction000134112
      WBInteraction000134114
      WBInteraction000134191
      WBInteraction000136255
      WBInteraction000149044
      WBInteraction000149478
      WBInteraction000151491
      WBInteraction000151847
      WBInteraction000159587
      WBInteraction000159991
      WBInteraction000163746
      WBInteraction000165246
      WBInteraction000174753
      WBInteraction000178875
      WBInteraction000180045
      WBInteraction000180158
      WBInteraction000181755
      WBInteraction000182106
      WBInteraction000183864
      WBInteraction000184292
      WBInteraction000184757
      WBInteraction000184932
      WBInteraction000185882
      WBInteraction000187370
      WBInteraction000191077
      WBInteraction000191248
      WBInteraction000191642
      WBInteraction000191678
      WBInteraction000192562
      WBInteraction000195918
      WBInteraction000197189
      WBInteraction000197925
      WBInteraction000198173
      WBInteraction000199371
      WBInteraction000200300
      WBInteraction000201263
      WBInteraction000201324
      WBInteraction000202087
      WBInteraction000202811
      WBInteraction000203172
      WBInteraction000205511
      WBInteraction000205757
      WBInteraction000206686
      WBInteraction000209123
      WBInteraction000209374
      WBInteraction000210175
      WBInteraction000211133
      WBInteraction000211830
      WBInteraction000213364
      WBInteraction000216741
      WBInteraction000217241
      WBInteraction000219851
      WBInteraction000220066
      WBInteraction000220297
      WBInteraction000220518
      WBInteraction000220899
      WBInteraction000221110
      WBInteraction000221831
      WBInteraction000222849
      WBInteraction000222951
      WBInteraction000224255
      WBInteraction000226169
      WBInteraction000226312
      WBInteraction000227997
      WBInteraction000230652
      WBInteraction000231828
      WBInteraction000233266
      WBInteraction000233661
      WBInteraction000234726
      WBInteraction000234809
      WBInteraction000235922
      WBInteraction000236098
      WBInteraction000238452
      WBInteraction000239690
      WBInteraction000239894
      WBInteraction000240050
      WBInteraction000240941
      WBInteraction000241590
      WBInteraction000241650
      WBInteraction000243358
      WBInteraction000245207
      WBInteraction000246713
      WBInteraction000247361
      WBInteraction000247921
      WBInteraction000247957
      WBInteraction000248373
      WBInteraction000249021
      WBInteraction000249294
      WBInteraction000249579
      WBInteraction000250554
      WBInteraction000250991
      WBInteraction000255659
      WBInteraction000255913
      WBInteraction000256077
      WBInteraction000258305
      WBInteraction000260133
      WBInteraction000260220
      WBInteraction000261692
      WBInteraction000262222
      WBInteraction000263046
      WBInteraction000263786
      WBInteraction000263864
      WBInteraction000264618
      WBInteraction000264764
      WBInteraction000265617
      WBInteraction000265868
      WBInteraction000266439
      WBInteraction000266701
      WBInteraction000270196
      WBInteraction000270385
      WBInteraction000271542
      WBInteraction000271899
      WBInteraction000272046
      WBInteraction000272859
      WBInteraction000273928
      WBInteraction000273946
      WBInteraction000274627
      WBInteraction000276923
      WBInteraction000277732
      WBInteraction000278257
      WBInteraction000279476
      WBInteraction000281558
      WBInteraction000281878
      WBInteraction000283228
      WBInteraction000283357
      WBInteraction000283958
      WBInteraction000284750
      WBInteraction000286025
      WBInteraction000286712
      WBInteraction000288738
      WBInteraction000291691
      WBInteraction000294667
      WBInteraction000295342
      WBInteraction000298955
      WBInteraction000299387
      WBInteraction000299868
      WBInteraction000300131
      WBInteraction000301310
      WBInteraction000302082
      WBInteraction000305515
      WBInteraction000307377
      WBInteraction000307524
      WBInteraction000309586
      WBInteraction000310266
      WBInteraction000310482
      WBInteraction000310997
      WBInteraction000311259
      WBInteraction000312219
      WBInteraction000314047
      WBInteraction000316876
      WBInteraction000317360
      WBInteraction000318087
      WBInteraction000318392
      WBInteraction000318751
      WBInteraction000321912
      WBInteraction000322914
      WBInteraction000323830
      WBInteraction000324036
      WBInteraction000324770
      WBInteraction000328521
      WBInteraction000328604
      WBInteraction000328910
      WBInteraction000329971
      WBInteraction000330120
      WBInteraction000333647
      WBInteraction000333673
      WBInteraction000334840
      WBInteraction000335398
      WBInteraction000336071
      WBInteraction000337286
      WBInteraction000338166
      WBInteraction000339148
      WBInteraction000340376
      WBInteraction000342620
      WBInteraction000343149
      WBInteraction000344620
      WBInteraction000345540
      WBInteraction000349589
      WBInteraction000352067
      WBInteraction000353059
      WBInteraction000354526
      WBInteraction000355277
      WBInteraction000356094
      WBInteraction000356412
      WBInteraction000356709
      WBInteraction000363351
      WBInteraction000366979
      WBInteraction000367867
      WBInteraction000369592
      WBInteraction000370090
      WBInteraction000371408
      WBInteraction000371663
      WBInteraction000372239
      WBInteraction000373175
      WBInteraction000374874
      WBInteraction000379279
      WBInteraction000379299
      WBInteraction000380040
      WBInteraction000381116
      WBInteraction000381168
      WBInteraction000382321
      WBInteraction000383942
      WBInteraction000383992
      WBInteraction000386496
      WBInteraction000391032
      WBInteraction000391779
      WBInteraction000391986
      WBInteraction000393688
      WBInteraction000398216
      WBInteraction000400013
      WBInteraction000402340
      WBInteraction000406130
      WBInteraction000409853
      WBInteraction000411774
      WBInteraction000412628
      WBInteraction000413797
      WBInteraction000415218
      WBInteraction000415371
      WBInteraction000415699
      WBInteraction000416269
      WBInteraction000417836
      WBInteraction000418066
      WBInteraction000419234
      WBInteraction000420413
      WBInteraction000422277
      WBInteraction000423125
      WBInteraction000427034
      WBInteraction000428184
      WBInteraction000429545
      WBInteraction000430890
      WBInteraction000431764
      WBInteraction000432498
      WBInteraction000433141
      WBInteraction000434036
      WBInteraction000434702
      WBInteraction000435203
      WBInteraction000436509
      WBInteraction000438065
      WBInteraction000439083
      WBInteraction000440076
      WBInteraction000441508
      WBInteraction000447987
      WBInteraction000449185
      WBInteraction000449190
      WBInteraction000449778
      WBInteraction000451967
      WBInteraction000452336
      WBInteraction000454795
      WBInteraction000455006
      WBInteraction000455644
      WBInteraction000458731
      WBInteraction000518626
      WBInteraction000518627
      WBInteraction000550206
      WBInteraction000562590
  Map_info: Map: X Position: -1.7753
    Positive: Positive_clone: T08A9 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00003435
    WBPaper00006437
    WBPaper00024209
    WBPaper00027295
    WBPaper00028482
    WBPaper00035289
    WBPaper00041167
    WBPaper00064841
    WBPaper00065877
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene