WormBase Tree Display for Gene: WBGene00004321

WBGene00004321 SMap: S_parent: Sequence: F54E7
  Identity: Version: 2
    Name: CGC_name: rcan-1 Paper_evidence: WBPaper00048397
          Person_evidence: WBPerson746
      Sequence_name: F54E7.7
      Molecular_name: F54E7.7
        F54E7.7.1
        CE31002
      Other_name: DSCR1L Accession_evidence: EMBL AF176115
        SC Accession_evidence: EMBL AF176115
        rcn-1 Paper_evidence: WBPaper00005829
          Person_evidence: WBPerson746
        CELE_F54E7.7 Accession_evidence: NDB BX284603
      Public_name: rcan-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:34 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 03 Sep 2015 10:04:07 WBPerson2970 Name_change: CGC_name: rcan-1
                Other_name: rcn-1
    Status: Live
  Gene_info (7)
  Disease_info: Experimental_model: DOID:14250 Homo sapiens Paper_evidence: WBPaper00005829
          Accession_evidence: OMIM 190685
          Curator_confirmed: WBPerson324
          Date_last_updated: 05 Jun 2017 00:00:00
    Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3040)
    Disease_relevance: DSCR1) gene is located in the Down Syndrome critical region (DSCR) of chromosome 21, and encodes an inhibitor of calcineurin-signalling pathways; in elegans, overexpression of rcan-1 could reproduce calcineurin loss-of-function phenotypes, providing in vivo proof of rcan-1 regulation of calcineurin; also, as with mbk-1, another DSCR gene ortholog in elegans, adjusting rcan-1 dosage could reverse the effects of its overexpression. Homo sapiens Paper_evidence: WBPaper00005829
          Accession_evidence: OMIM 190685
          Curator_confirmed: WBPerson324
          Date_last_updated: 05 Jun 2017 00:00:00
  Models_disease_in_annotation: WBDOannot00000131
  Molecular_info: Corresponding_CDS: F54E7.7
    Corresponding_transcript: F54E7.7.1
    Other_sequence (28)
    Associated_feature: WBsf666918
      WBsf992489
      WBsf992490
      WBsf992491
      WBsf226716
  Experimental_info: RNAi_result: WBRNAi00048353 Inferred_automatically: RNAi_primary
      WBRNAi00015642 Inferred_automatically: RNAi_primary
      WBRNAi00005533 Inferred_automatically: RNAi_primary
      WBRNAi00027915 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr2548
      Expr11062
      Expr13659
      Expr1011498
      Expr1032146
      Expr1152149
      Expr2015278
      Expr2033512
    Drives_construct: WBCnstr00008158
      WBCnstr00010850
      WBCnstr00037927
      WBCnstr00039931
    Construct_product: WBCnstr00008158
      WBCnstr00037927
      WBCnstr00039931
    Antibody: WBAntibody00002649
    Microarray_results (20)
    Expression_cluster (198)
    Interaction: WBInteraction000002072
      WBInteraction000003704
      WBInteraction000029551
      WBInteraction000031616
      WBInteraction000122698
      WBInteraction000122705
      WBInteraction000122836
      WBInteraction000133553
      WBInteraction000134211
      WBInteraction000173741
      WBInteraction000223383
      WBInteraction000231866
      WBInteraction000255160
      WBInteraction000307748
      WBInteraction000448887
      WBInteraction000449477
      WBInteraction000501864
      WBInteraction000501865
      WBInteraction000507658
      WBInteraction000507659
      WBInteraction000507663
      WBInteraction000507664
      WBInteraction000507665
      WBInteraction000507666
      WBInteraction000507667
      WBInteraction000507668
      WBInteraction000507669
      WBInteraction000507670
      WBInteraction000507671
      WBInteraction000507672
      WBInteraction000507674
      WBInteraction000507675
      WBInteraction000507676
      WBInteraction000507677
      WBInteraction000507678
      WBInteraction000507679
      WBInteraction000507680
      WBInteraction000507681
      WBInteraction000507682
      WBInteraction000507683
      WBInteraction000507684
      WBInteraction000507685
      WBInteraction000507686
      WBInteraction000507687
      WBInteraction000507688
      WBInteraction000507689
      WBInteraction000507690
      WBInteraction000507691
      WBInteraction000507692
      WBInteraction000507693
      WBInteraction000507694
      WBInteraction000507695
      WBInteraction000507696
      WBInteraction000507697
      WBInteraction000507698
      WBInteraction000507699
      WBInteraction000507700
      WBInteraction000507701
      WBInteraction000507702
      WBInteraction000507703
      WBInteraction000507704
      WBInteraction000507705
      WBInteraction000507706
      WBInteraction000507707
      WBInteraction000507708
      WBInteraction000507709
      WBInteraction000507710
      WBInteraction000507711
      WBInteraction000507712
      WBInteraction000507713
      WBInteraction000507714
      WBInteraction000507715
      WBInteraction000507716
      WBInteraction000507717
      WBInteraction000507718
      WBInteraction000507719
      WBInteraction000507720
      WBInteraction000507721
      WBInteraction000507722
      WBInteraction000507723
      WBInteraction000507724
      WBInteraction000507725
      WBInteraction000507726
      WBInteraction000507727
      WBInteraction000507728
      WBInteraction000507729
      WBInteraction000507730
      WBInteraction000507731
      WBInteraction000507732
      WBInteraction000507733
      WBInteraction000507734
      WBInteraction000507735
      WBInteraction000507736
      WBInteraction000507737
      WBInteraction000507738
      WBInteraction000507739
      WBInteraction000507740
      WBInteraction000507741
      WBInteraction000507742
      WBInteraction000507743
      WBInteraction000507744
      WBInteraction000507745
      WBInteraction000507746
      WBInteraction000507747
      WBInteraction000507748
      WBInteraction000507749
      WBInteraction000507750
      WBInteraction000507751
      WBInteraction000507752
      WBInteraction000507753
      WBInteraction000507754
      WBInteraction000507755
      WBInteraction000507756
      WBInteraction000507757
      WBInteraction000507758
      WBInteraction000507759
      WBInteraction000507760
      WBInteraction000507761
      WBInteraction000507762
      WBInteraction000507763
      WBInteraction000507764
      WBInteraction000507765
      WBInteraction000507766
      WBInteraction000507767
      WBInteraction000507768
      WBInteraction000507769
      WBInteraction000507770
      WBInteraction000507771
      WBInteraction000507772
      WBInteraction000507773
      WBInteraction000507774
      WBInteraction000507775
      WBInteraction000507776
      WBInteraction000507777
      WBInteraction000507778
      WBInteraction000507779
      WBInteraction000507780
      WBInteraction000507781
      WBInteraction000507782
      WBInteraction000507783
      WBInteraction000507784
      WBInteraction000507785
      WBInteraction000507786
      WBInteraction000507787
      WBInteraction000507788
      WBInteraction000507789
      WBInteraction000507790
      WBInteraction000507791
      WBInteraction000507792
      WBInteraction000507793
      WBInteraction000507794
      WBInteraction000507795
      WBInteraction000507796
      WBInteraction000507797
      WBInteraction000507798
      WBInteraction000507799
      WBInteraction000507800
      WBInteraction000507801
      WBInteraction000507802
      WBInteraction000507803
      WBInteraction000507804
      WBInteraction000507805
      WBInteraction000507806
      WBInteraction000507807
      WBInteraction000521481
      WBInteraction000541216
      WBInteraction000547064
      WBInteraction000555301
      WBInteraction000568351
  Map_info: Map: III Position: -1.45588 Error: 0.000648
    Positive: Positive_clone: F54E7 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5250
        5049
    Pseudo_map_position
  Reference (25)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene