WormBase Tree Display for Gene: WBGene00001235

WBGene00001235 SMap: S_parent: Sequence: Y41C4A
  Identity: Version: 1
    Name: CGC_name: elb-1 Person_evidence: WBPerson322
      Sequence_name: Y41C4A.10
      Molecular_name: Y41C4A.10
        Y41C4A.10.1
        CE20250
      Other_name: 3L686 Accession_evidence: EMBL AF326942
        CELE_Y41C4A.10 Accession_evidence: NDB BX284603
      Public_name: elb-1
    DB_info: Database: AceView gene 3M808
        WormQTL gene WBGene00001235
        WormFlux gene WBGene00001235
        NDB locus_tag CELE_Y41C4A.10
        Panther gene CAEEL|WormBase=WBGene00001235|UniProtKB=G5ECR7
          family PTHR13248
        NCBI gene 176605
        RefSeq protein NM_067116.7
        TREEFAM TREEFAM_ID TF325964
        TrEMBL UniProtAcc G5ECR7
        UniProt_GCRP UniProtAcc G5ECR7
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:23 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: elb
    Allele (15)
    Strain: WBStrain00051184
    RNASeq_FPKM (74)
    GO_annotation: 00012393
      00012394
      00012395
      00012396
      00012397
      00108490
      00108491
      00108492
    Contained_in_operon: CEOP3728
    Ortholog (33)
    Structured_description: Concise_description: elb-1 encodes an Elongin B ortholog required for chromosome condensationand segregation during mitosis and meiotic division II, and also for cellproliferation (probably through degradation of CKI-1); elb-1(RNAi) animalstend to arrest at the second meiotic cell division, with escapers showingmany other defects in chromosomal dynamics and cell cycle control such asabnormal pronuclear rotation and cortical protrusion, aberrant chromosomalstructures in the intestine, and deficient germ cell proliferation; ELB-1interacts with ELC-1 and ELC-2 in bacterial two-hybrid experiments. Paper_evidence: WBPaper00026616
          Curator_confirmed: WBPerson567
          Date_last_updated: 23 Aug 2006 00:00:00
      Automated_description: Enables protein domain specific binding activity. Predicted to be involved in transcription elongation by RNA polymerase II. Part of Cul2-RING ubiquitin ligase complex. Is an ortholog of human ELOB (elongin B). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y41C4A.10
    Corresponding_transcript: Y41C4A.10.1
    Other_sequence: AF326942
      CBC12953_1
      CRC11177_1
    Associated_feature (3)
  Experimental_info: RNAi_result (39)
    Expr_pattern: Expr1016832
      Expr1030783
      Expr1159837
      Expr2011270
      Expr2029506
    Microarray_results (19)
    Expression_cluster (96)
    Interaction: WBInteraction000009447
      WBInteraction000030466
      WBInteraction000030467
      WBInteraction000105455
      WBInteraction000118840
      WBInteraction000125022
      WBInteraction000127618
      WBInteraction000127746
      WBInteraction000127752
      WBInteraction000127804
      WBInteraction000127826
      WBInteraction000128233
      WBInteraction000128234
      WBInteraction000128235
      WBInteraction000128236
      WBInteraction000128237
      WBInteraction000128238
      WBInteraction000128334
      WBInteraction000128357
      WBInteraction000130390
      WBInteraction000130407
      WBInteraction000130705
      WBInteraction000130861
      WBInteraction000131222
      WBInteraction000131656
      WBInteraction000131675
      WBInteraction000131691
      WBInteraction000131745
      WBInteraction000131830
      WBInteraction000131943
      WBInteraction000132323
      WBInteraction000132452
      WBInteraction000132563
      WBInteraction000132602
      WBInteraction000132670
      WBInteraction000132773
      WBInteraction000132871
      WBInteraction000132885
      WBInteraction000149053
      WBInteraction000155463
      WBInteraction000156215
      WBInteraction000158023
      WBInteraction000158024
      WBInteraction000166834
      WBInteraction000169202
      WBInteraction000182754
      WBInteraction000217877
      WBInteraction000300571
      WBInteraction000314380
      WBInteraction000331916
      WBInteraction000362378
      WBInteraction000444246
      WBInteraction000504671
      WBInteraction000516537
      WBInteraction000521111
      WBInteraction000522333
      WBInteraction000522937
      WBInteraction000522938
      WBInteraction000522939
      WBInteraction000522940
      WBInteraction000522941
      WBInteraction000523063
      WBInteraction000540057
      WBInteraction000540058
      WBInteraction000540076
      WBInteraction000541852
      WBInteraction000548878
      WBInteraction000552150
      WBInteraction000561479
      WBInteraction000567411
      WBInteraction000568047
      WBInteraction000568519
      WBInteraction000568935
      WBInteraction000576542
      WBInteraction000579981
      WBInteraction000584913
  Map_info: Map: III Position: 12.0059 Error: 0.028827
    Positive: Positive_clone: Y41C4A Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00024321
    WBPaper00024458
    WBPaper00026616
    WBPaper00027315
    WBPaper00030834
    WBPaper00037728
    WBPaper00038491
    WBPaper00041771
    WBPaper00048493
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene