WormBase Tree Display for Gene: WBGene00000784

WBGene00000784 SMap: S_parent: Sequence: F44C4
  Identity: Version: 1
    Name: CGC_name: cpr-4
      Sequence_name: F44C4.3
      Molecular_name: F44C4.3
        F44C4.3.1
        CE07251
      Other_name: CELE_F44C4.3 Accession_evidence: NDB BX284605
      Public_name: cpr-4
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cpr
    Allele (33)
    Legacy_information: [C.elegansII] NMK. Encodes protein with significant similarity to proteases of Cathepsin B family (EST cm14e3). [IA]
    Strain: WBStrain00033148
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog (44)
    Paralog (28)
    Structured_description: Concise_description: cpr-4 encodes a cathepsin B-like cysteine protease expressed at all life stages. Paper_evidence: WBPaper00002373
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables cysteine-type endopeptidase activity. Involved in cellular response to UV; cellular response to gamma radiation; and proteolysis involved in protein catabolic process. Located in extracellular region. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9351 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:11054 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:2671 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:9352 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:2377 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:10941 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:12842 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:3068 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:4914 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:1612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
  Molecular_info: Corresponding_CDS: F44C4.3
    Corresponding_transcript: F44C4.3.1
    Other_sequence (375)
    Associated_feature: WBsf646890
      WBsf1000314
      WBsf231894
  Experimental_info: RNAi_result: WBRNAi00007344 Inferred_automatically: RNAi_primary
      WBRNAi00115171 Inferred_automatically: RNAi_primary
      WBRNAi00047258 Inferred_automatically: RNAi_primary
    Expr_pattern (7)
    Drives_construct: WBCnstr00037278
      WBCnstr00039152
    Construct_product: WBCnstr00037278
    Microarray_results (19)
    Expression_cluster (354)
    Interaction: WBInteraction000103482
      WBInteraction000109638
      WBInteraction000119607
      WBInteraction000137120
      WBInteraction000137265
      WBInteraction000141031
      WBInteraction000151172
      WBInteraction000157641
      WBInteraction000159574
      WBInteraction000165292
      WBInteraction000182500
      WBInteraction000184952
      WBInteraction000185964
      WBInteraction000186019
      WBInteraction000187302
      WBInteraction000194346
      WBInteraction000200973
      WBInteraction000201209
      WBInteraction000204103
      WBInteraction000208227
      WBInteraction000211830
      WBInteraction000213346
      WBInteraction000214573
      WBInteraction000215335
      WBInteraction000217862
      WBInteraction000218558
      WBInteraction000227108
      WBInteraction000227253
      WBInteraction000228477
      WBInteraction000230745
      WBInteraction000230851
      WBInteraction000231557
      WBInteraction000231645
      WBInteraction000239145
      WBInteraction000239307
      WBInteraction000239539
      WBInteraction000241092
      WBInteraction000242381
      WBInteraction000245061
      WBInteraction000246931
      WBInteraction000250020
      WBInteraction000254078
      WBInteraction000254516
      WBInteraction000259449
      WBInteraction000260762
      WBInteraction000261910
      WBInteraction000262935
      WBInteraction000263623
      WBInteraction000264581
      WBInteraction000266630
      WBInteraction000266805
      WBInteraction000269459
      WBInteraction000271299
      WBInteraction000271669
      WBInteraction000280283
      WBInteraction000282191
      WBInteraction000282805
      WBInteraction000286682
      WBInteraction000290046
      WBInteraction000291436
      WBInteraction000292255
      WBInteraction000292814
      WBInteraction000294588
      WBInteraction000295400
      WBInteraction000296005
      WBInteraction000296229
      WBInteraction000299289
      WBInteraction000299605
      WBInteraction000301028
      WBInteraction000301325
      WBInteraction000304126
      WBInteraction000310150
      WBInteraction000312365
      WBInteraction000312638
      WBInteraction000313686
      WBInteraction000314176
      WBInteraction000318391
      WBInteraction000318517
      WBInteraction000319170
      WBInteraction000321373
      WBInteraction000322464
      WBInteraction000322776
      WBInteraction000323616
      WBInteraction000327172
      WBInteraction000327616
      WBInteraction000329640
      WBInteraction000329852
      WBInteraction000333709
      WBInteraction000341618
      WBInteraction000348553
      WBInteraction000349214
      WBInteraction000353050
      WBInteraction000353319
      WBInteraction000356574
      WBInteraction000357568
      WBInteraction000357983
      WBInteraction000358567
      WBInteraction000360028
      WBInteraction000361475
      WBInteraction000363507
      WBInteraction000363925
      WBInteraction000363973
      WBInteraction000364095
      WBInteraction000367548
      WBInteraction000368006
      WBInteraction000368426
      WBInteraction000372266
      WBInteraction000377089
      WBInteraction000385436
      WBInteraction000386595
      WBInteraction000387039
      WBInteraction000387195
      WBInteraction000387529
      WBInteraction000394488
      WBInteraction000395353
      WBInteraction000398164
      WBInteraction000401051
      WBInteraction000401361
      WBInteraction000402208
      WBInteraction000410480
      WBInteraction000410811
      WBInteraction000413234
      WBInteraction000415227
      WBInteraction000416710
      WBInteraction000420427
      WBInteraction000420574
      WBInteraction000426373
      WBInteraction000428110
      WBInteraction000429956
      WBInteraction000430287
      WBInteraction000440504
      WBInteraction000442144
      WBInteraction000445105
      WBInteraction000446025
      WBInteraction000447899
      WBInteraction000448928
      WBInteraction000449416
      WBInteraction000452469
      WBInteraction000454365
      WBInteraction000546303
      WBInteraction000550081
      WBInteraction000552002
      WBInteraction000560192
      WBInteraction000563335
      WBInteraction000571981
      WBInteraction000578622
  Map_info: Map: V Position: 0.113422 Error: 0.001009
    Positive: Positive_clone: F44C4 Inferred_automatically: From sequence, transcript, pseudogene data
        W02B2 Author_evidence: Larminie CGC
        ZK1055
    Pseudo_map_position
  Reference (15)
  Remark: data received 11/94
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene