WormBase Tree Display for Gene: WBGene00000498

WBGene00000498 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: Y39H10A
  Identity: Version: 1
    Name: CGC_name: chk-1 Person_evidence: WBPerson1551
      Sequence_name: Y39H10A.7
      Molecular_name: Y39H10A.7a
        Y39H10A.7a.1
        CE26076
        Y39H10A.7b
        CE33867
        Y39H10A.7b.1
      Other_name: Y39H10A.a Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        CELE_Y39H10A.7 Accession_evidence: NDB BX284605
      Public_name: chk-1
    DB_info: Database (14)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: chk
    Allele (45)
    Strain: WBStrain00034800
      WBStrain00034803
    RNASeq_FPKM (74)
    GO_annotation (23)
    Contained_in_operon: CEOP5515
    Ortholog (57)
    Paralog (30)
    Structured_description: Concise_description: chk-1 encodes a CHK1-like serine threonin protein kinase that affects fertility. Paper_evidence: WBPaper00005039
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable protein serine/threonine kinase activity. Involved in embryo development and mitotic DNA replication checkpoint signaling. Predicted to be located in nucleus. Expressed in germ line. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human CHEK1 (checkpoint kinase 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:1793 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1925)
      EFO:MONDO:0014769 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1925)
  Molecular_info: Corresponding_CDS: Y39H10A.7a
      Y39H10A.7b
    Corresponding_transcript (2)
    Other_sequence (15)
    Associated_feature: WBsf652545
      WBsf668844
      WBsf668845
      WBsf668846
      WBsf999681
      WBsf999682
      WBsf1019419
      WBsf233520
      WBsf233521
      WBsf233522
  Experimental_info: RNAi_result (53)
    Expr_pattern: Expr3082
      Expr4894
      Expr9219
      Expr1011525
      Expr1030294
      Expr1159784
      Expr1200236
      Expr2009991
      Expr2028232
    Drives_construct: WBCnstr00037496
      WBCnstr00038171
    Construct_product: WBCnstr00037496
      WBCnstr00038171
    Microarray_results (26)
    Expression_cluster (145)
    Interaction: WBInteraction000006025
      WBInteraction000006643
      WBInteraction000006724
      WBInteraction000006990
      WBInteraction000007144
      WBInteraction000007289
      WBInteraction000007307
      WBInteraction000007362
      WBInteraction000007460
      WBInteraction000007499
      WBInteraction000007551
      WBInteraction000007619
      WBInteraction000008798
      WBInteraction000008991
      WBInteraction000029844
      WBInteraction000032663
      WBInteraction000032664
      WBInteraction000033011
      WBInteraction000033381
      WBInteraction000035793
      WBInteraction000037209
      WBInteraction000037417
      WBInteraction000037765
      WBInteraction000038938
      WBInteraction000039022
      WBInteraction000039610
      WBInteraction000040540
      WBInteraction000040632
      WBInteraction000040633
      WBInteraction000041842
      WBInteraction000042460
      WBInteraction000042690
      WBInteraction000043409
      WBInteraction000043515
      WBInteraction000043772
      WBInteraction000043804
      WBInteraction000044194
      WBInteraction000044400
      WBInteraction000045221
      WBInteraction000045540
      WBInteraction000045749
      WBInteraction000046989
      WBInteraction000047490
      WBInteraction000047904
      WBInteraction000049037
      WBInteraction000050634
      WBInteraction000050635
      WBInteraction000050636
      WBInteraction000106225
      WBInteraction000106984
      WBInteraction000110927
      WBInteraction000110944
      WBInteraction000110969
      WBInteraction000111276
      WBInteraction000111822
      WBInteraction000111954
      WBInteraction000112545
      WBInteraction000112641
      WBInteraction000112729
      WBInteraction000112831
      WBInteraction000114693
      WBInteraction000115943
      WBInteraction000117455
      WBInteraction000117480
      WBInteraction000117569
      WBInteraction000117833
      WBInteraction000122584
      WBInteraction000123346
      WBInteraction000125511
      WBInteraction000125512
      WBInteraction000136397
      WBInteraction000136796
      WBInteraction000144784
      WBInteraction000146455
      WBInteraction000153535
      WBInteraction000153559
      WBInteraction000153560
      WBInteraction000153561
      WBInteraction000153977
      WBInteraction000153978
      WBInteraction000153979
      WBInteraction000154146
      WBInteraction000154149
      WBInteraction000154157
      WBInteraction000154160
      WBInteraction000154163
      WBInteraction000154267
      WBInteraction000154400
      WBInteraction000154409
      WBInteraction000154423
      WBInteraction000155499
      WBInteraction000155765
      WBInteraction000156197
      WBInteraction000156248
      WBInteraction000156323
      WBInteraction000156354
      WBInteraction000162260
      WBInteraction000169440
      WBInteraction000169682
      WBInteraction000185051
      WBInteraction000185452
      WBInteraction000202140
      WBInteraction000211299
      WBInteraction000214564
      WBInteraction000217896
      WBInteraction000218210
      WBInteraction000245820
      WBInteraction000262176
      WBInteraction000267934
      WBInteraction000272332
      WBInteraction000298401
      WBInteraction000310579
      WBInteraction000321652
      WBInteraction000321784
      WBInteraction000323972
      WBInteraction000341982
      WBInteraction000359410
      WBInteraction000359411
      WBInteraction000385095
      WBInteraction000399716
      WBInteraction000403218
      WBInteraction000414552
      WBInteraction000445070
      WBInteraction000463936
      WBInteraction000464702
      WBInteraction000470642
      WBInteraction000472962
      WBInteraction000500581
      WBInteraction000501380
      WBInteraction000520555
      WBInteraction000520556
      WBInteraction000521707
      WBInteraction000521709
      WBInteraction000525290
      WBInteraction000539829
      WBInteraction000539830
      WBInteraction000550899
      WBInteraction000550900
  Map_info: Map: V Position: -8.01265 Error: 0.002467
    Positive: Positive_clone: Y39H10A Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5377
    Pseudo_map_position
  Reference (51)
  Remark: Sequence connection from [Boulton S, Vidal M]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene