WormBase Tree Display for Gene: WBGene00000382

WBGene00000382 SMap: S_parent: Sequence: C43E11
  Identity: Version: 1
    Name: CGC_name: cdc-6
      Sequence_name: C43E11.10
      Molecular_name: C43E11.10
        C43E11.10.1
        CE08688
      Other_name: CELE_C43E11.10 Accession_evidence: NDB BX284601
      Public_name: cdc-6
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cdc
    Allele (36)
    Strain: WBStrain00037796
    RNASeq_FPKM (74)
    GO_annotation (15)
    Contained_in_operon: CEOP1172
    Ortholog (31)
    Paralog: WBGene00012650 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: cdc-6 encodes a homolog of an origin complex component (CDC6) which in yeast controls the start of DNA replication, and also has a distant paralog (Y39A1A.12) within the C. elegans genome; CDC-6 is superficially dispensable for embryonic viability, perhaps because of redundancy with Y39A1A.12. Paper_evidence: WBPaper00013079
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in mitotic DNA replication checkpoint signaling. Located in condensed nuclear chromosome; cytoplasm; and nucleolus. Expressed in seam cell. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 5. Is an ortholog of human CDC6 (cell division cycle 6). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080516 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1744)
  Molecular_info: Corresponding_CDS: C43E11.10
    Corresponding_transcript: C43E11.10.1
    Other_sequence (19)
    Associated_feature: WBsf649089
      WBsf664135
      WBsf219260
  Experimental_info: RNAi_result (20)
    Expr_pattern: Expr4680
      Expr4681
      Expr9926
      Expr1028747
      Expr1030208
      Expr1146367
      Expr2009790
      Expr2028030
    Drives_construct: WBCnstr00037581
    Construct_product: WBCnstr00000444
      WBCnstr00000445
      WBCnstr00000446
      WBCnstr00000447
      WBCnstr00007279
      WBCnstr00009675
      WBCnstr00012168
      WBCnstr00015914
      WBCnstr00037581
    Antibody: WBAntibody00001255
    Microarray_results (20)
    Expression_cluster (111)
    Interaction: WBInteraction000034401
      WBInteraction000035509
      WBInteraction000038270
      WBInteraction000038271
      WBInteraction000038272
      WBInteraction000038411
      WBInteraction000038920
      WBInteraction000040065
      WBInteraction000040425
      WBInteraction000042810
      WBInteraction000042811
      WBInteraction000042988
      WBInteraction000042989
      WBInteraction000046891
      WBInteraction000047524
      WBInteraction000048724
      WBInteraction000049935
      WBInteraction000050556
      WBInteraction000104723
      WBInteraction000106053
      WBInteraction000106357
      WBInteraction000107422
      WBInteraction000109213
      WBInteraction000109951
      WBInteraction000110019
      WBInteraction000110578
      WBInteraction000111861
      WBInteraction000114627
      WBInteraction000114894
      WBInteraction000124574
      WBInteraction000127059
      WBInteraction000127731
      WBInteraction000127732
      WBInteraction000127733
      WBInteraction000127734
      WBInteraction000127735
      WBInteraction000127736
      WBInteraction000127737
      WBInteraction000133008
      WBInteraction000134972
      WBInteraction000138777
      WBInteraction000140587
      WBInteraction000145797
      WBInteraction000151526
      WBInteraction000151964
      WBInteraction000153535
      WBInteraction000153536
      WBInteraction000153537
      WBInteraction000153538
      WBInteraction000153539
      WBInteraction000153540
      WBInteraction000163246
      WBInteraction000163636
      WBInteraction000164396
      WBInteraction000168202
      WBInteraction000169083
      WBInteraction000180787
      WBInteraction000185640
      WBInteraction000185849
      WBInteraction000192347
      WBInteraction000192675
      WBInteraction000198607
      WBInteraction000206331
      WBInteraction000217468
      WBInteraction000219113
      WBInteraction000225027
      WBInteraction000231201
      WBInteraction000235363
      WBInteraction000235364
      WBInteraction000235365
      WBInteraction000242257
      WBInteraction000264130
      WBInteraction000272660
      WBInteraction000273666
      WBInteraction000273667
      WBInteraction000281224
      WBInteraction000290210
      WBInteraction000293336
      WBInteraction000304834
      WBInteraction000319680
      WBInteraction000320273
      WBInteraction000332428
      WBInteraction000333926
      WBInteraction000339646
      WBInteraction000354086
      WBInteraction000357348
      WBInteraction000358732
      WBInteraction000367086
      WBInteraction000373841
      WBInteraction000393914
      WBInteraction000394700
      WBInteraction000403757
      WBInteraction000403758
      WBInteraction000403759
      WBInteraction000406535
      WBInteraction000415426
      WBInteraction000415449
      WBInteraction000423360
      WBInteraction000423761
      WBInteraction000429143
      WBInteraction000437998
      WBInteraction000443424
      WBInteraction000458749
      WBInteraction000459451
      WBInteraction000463679
      WBInteraction000466088
      WBInteraction000466089
      WBInteraction000467568
      WBInteraction000467861
      WBInteraction000471505
      WBInteraction000471506
      WBInteraction000473137
      WBInteraction000474918
      WBInteraction000475220
      WBInteraction000502910
      WBInteraction000523244
      WBInteraction000542769
      WBInteraction000542772
  Map_info: Map: I Position: -1.51655 Error: 0.002838
    Positive: Positive_clone: C43E11 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (10)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene