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WormBase Tree Display for Gene: WBGene00001093

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Name Class

WBGene00001093SMapS_parentSequenceT12E12
IdentityVersion1
NameCGC_namedrp-1Person_evidenceWBPerson733
Sequence_nameT12E12.4
Molecular_nameT12E12.4a
T12E12.4a.1
CE30172
T12E12.4b
CE30173
T12E12.4a.2
T12E12.4b.1
T12E12.4b.2
Other_nameCELE_T12E12.4Accession_evidenceNDBBX284604
Public_namedrp-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:23WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdrp
Allele (45)
StrainWBStrain00005196
WBStrain00007389
WBStrain00007408
WBStrain00007414
RNASeq_FPKM (74)
GO_annotation (30)
Contained_in_operonCEOP4168
Ortholog (39)
ParalogWBGene00001134Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00001130Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptiondrp-1 encodes a dynamin-related protein, orthologous to Dnm1p in S. cerevisiae and DRP1 in mammals, that is required for severing of the mitochondrial outer membrane during mitochondrial division.Paper_evidenceWBPaper00003790
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable GTP binding activity; GTPase activity; and microtubule binding activity. Involved in apoptotic mitochondrial changes; embryo development; and mitochondrial fission. Located in mitochondrion. Expressed in several structures, including germ line; non-striated muscle; preanal ganglion; rectal muscle; and somatic nervous system. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in Alzheimer's disease; encephalopathy due to defective mitochondrial and peroxisomal fission 1; optic atrophy 5; and pulmonary fibrosis. Is an ortholog of human DNM1L (dynamin 1 like).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:14330Homo sapiensPaper_evidenceWBPaper00057005
Curator_confirmedWBPerson324
Date_last_updated20 Feb 2020 00:00:00
Potential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2973)
DOID:0070347Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2973)
DOID:0111438Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2973)
DOID:3770Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2973)
Models_disease_assertedWBDOannot00000741
Molecular_infoCorresponding_CDST12E12.4a
T12E12.4b
Corresponding_transcriptT12E12.4a.1
T12E12.4a.2
T12E12.4b.1
T12E12.4b.2
Other_sequence (72)
Associated_featureWBsf655022
WBsf660150
WBsf981759
WBsf996535
WBsf228316
WBsf228317
WBsf228318
Experimental_infoRNAi_resultWBRNAi00082151Inferred_automaticallyRNAi_primary
WBRNAi00077582Inferred_automaticallyRNAi_primary
WBRNAi00088569Inferred_automaticallyRNAi_primary
WBRNAi00080547Inferred_automaticallyRNAi_primary
WBRNAi00082152Inferred_automaticallyRNAi_primary
WBRNAi00053217Inferred_automaticallyRNAi_primary
WBRNAi00082139Inferred_automaticallyRNAi_primary
WBRNAi00109957Inferred_automaticallyRNAi_primary
WBRNAi00082143Inferred_automaticallyRNAi_primary
WBRNAi00088575Inferred_automaticallyRNAi_primary
WBRNAi00082149Inferred_automaticallyRNAi_primary
WBRNAi00082150Inferred_automaticallyRNAi_primary
WBRNAi00026282Inferred_automaticallyRNAi_primary
WBRNAi00109891Inferred_automaticallyRNAi_primary
WBRNAi00097907Inferred_automaticallyRNAi_primary
WBRNAi00092289Inferred_automaticallyRNAi_primary
WBRNAi00087461Inferred_automaticallyRNAi_primary
WBRNAi00087458Inferred_automaticallyRNAi_primary
WBRNAi00087456Inferred_automaticallyRNAi_primary
WBRNAi00077585Inferred_automaticallyRNAi_primary
WBRNAi00088561Inferred_automaticallyRNAi_primary
WBRNAi00082148Inferred_automaticallyRNAi_primary
WBRNAi00092295Inferred_automaticallyRNAi_primary
WBRNAi00008038Inferred_automaticallyRNAi_primary
WBRNAi00109121Inferred_automaticallyRNAi_primary
WBRNAi00091128Inferred_automaticallyRNAi_primary
WBRNAi00087457Inferred_automaticallyRNAi_primary
WBRNAi00009165Inferred_automaticallyRNAi_primary
WBRNAi00078878Inferred_automaticallyRNAi_primary
WBRNAi00114606Inferred_automaticallyRNAi_primary
WBRNAi00109924Inferred_automaticallyRNAi_primary
WBRNAi00112343Inferred_automaticallyRNAi_primary
WBRNAi00087460Inferred_automaticallyRNAi_primary
WBRNAi00087459Inferred_automaticallyRNAi_primary
WBRNAi00027905Inferred_automaticallyRNAi_primary
WBRNAi00091130Inferred_automaticallyRNAi_primary
Expr_patternExpr543
Expr11473
Expr12437
Expr1017306
Expr1030697
Expr1156803
Expr2011094
Expr2029330
Drives_constructWBCnstr00012431
WBCnstr00037085
Construct_productWBCnstr00005418
WBCnstr00005420
WBCnstr00009299
WBCnstr00012431
WBCnstr00019040
WBCnstr00037085
AntibodyWBAntibody00001689
Microarray_results (33)
Expression_cluster (152)
InteractionWBInteraction000000966
WBInteraction000009229
WBInteraction000009232
WBInteraction000030050
WBInteraction000039620
WBInteraction000041945
WBInteraction000045137
WBInteraction000045580
WBInteraction000047096
WBInteraction000047562
WBInteraction000047610
WBInteraction000048141
WBInteraction000050096
WBInteraction000050398
WBInteraction000050399
WBInteraction000050400
WBInteraction000050503
WBInteraction000050504
WBInteraction000050505
WBInteraction000051721
WBInteraction000135884
WBInteraction000142160
WBInteraction000165517
WBInteraction000170580
WBInteraction000174581
WBInteraction000180200
WBInteraction000187401
WBInteraction000196739
WBInteraction000197740
WBInteraction000198273
WBInteraction000202130
WBInteraction000218211
WBInteraction000226618
WBInteraction000227179
WBInteraction000231017
WBInteraction000234474
WBInteraction000241678
WBInteraction000248333
WBInteraction000251844
WBInteraction000252915
WBInteraction000257865
WBInteraction000263060
WBInteraction000264846
WBInteraction000281569
WBInteraction000291692
WBInteraction000293062
WBInteraction000303596
WBInteraction000303849
WBInteraction000304258
WBInteraction000311021
WBInteraction000320810
WBInteraction000327934
WBInteraction000336984
WBInteraction000345626
WBInteraction000352788
WBInteraction000353791
WBInteraction000382686
WBInteraction000386873
WBInteraction000390783
WBInteraction000393055
WBInteraction000395634
WBInteraction000396851
WBInteraction000405558
WBInteraction000406873
WBInteraction000412515
WBInteraction000425230
WBInteraction000429953
WBInteraction000440293
WBInteraction000441833
WBInteraction000442322
WBInteraction000443831
WBInteraction000453920
WBInteraction000454585
WBInteraction000454999
WBInteraction000459638
WBInteraction000470667
WBInteraction000501339
WBInteraction000501340
WBInteraction000501344
WBInteraction000512487
WBInteraction000518847
WBInteraction000522198
WBInteraction000522217
WBInteraction000537090
WBInteraction000537184
WBInteraction000537217
WBInteraction000537250
WBInteraction000537453
WBInteraction000537458
WBInteraction000538852
WBInteraction000542369
WBInteraction000542370
WBInteraction000547679
WBInteraction000548956
WBInteraction000549150
WBInteraction000549390
WBInteraction000550211
WBInteraction000558497
WBInteraction000559471
WBInteraction000560424
WBInteraction000560425
WBInteraction000563276
WBInteraction000564954
WBInteraction000567413
WBInteraction000568867
WBInteraction000571312
WBInteraction000571769
WBInteraction000574805
WBInteraction000577464
WBInteraction000579638
WBInteraction000579968
WBInteraction000582942
WBInteraction000585978
WBInteraction000586631
Map_infoMapIVPosition1.82105Error0.005501
PositivePositive_cloneT12E12Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (93)
RemarkSequence connection from [Labrousse AM, van der Bliek AM]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene