pfd-2 encodes a putative prefoldin subunit 2, orthologous to human PFDN2, that is required for normal microtubule growth; pfd-2(RNAi) animals have sterile progeny, and pfd-2(RNAi) embryos show a reduced microtubule growth rate; in mass RNAi assays, PFD-2 is required for normal pronuclear migration, embryonic and larval viability, body shape, and locomotion.
Predicted to enable protein folding chaperone. Predicted to be involved in protein folding. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Is an ortholog of human PFDN2 (prefoldin subunit 2).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.