WormBase Tree Display for Gene: WBGene00002070

WBGene00002070 Evidence: Person_evidence: WBPerson842
  SMap: S_parent: Sequence: K07A1
  Identity: Version: 1
    Name: CGC_name: ile-1 Person_evidence: WBPerson842
      Sequence_name: K07A1.8
      Molecular_name: K07A1.8
        K07A1.8.1
        CE11854
      Other_name: CELE_K07A1.8 Accession_evidence: NDB BX284601
      Public_name: ile-1
    DB_info: Database: AceView gene 1K186
        WormQTL gene WBGene00002070
        WormFlux gene WBGene00002070
        NDB locus_tag CELE_K07A1.8
        Panther gene CAEEL|WormBase=WBGene00002070|UniProtKB=G5EDE8
          family PTHR12223
        NCBI gene 172799
        RefSeq protein NM_060147.7
        TREEFAM TREEFAM_ID TF313311
        TrEMBL UniProtAcc G5EDE8
        UniProt_GCRP UniProtAcc G5EDE8
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:26 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ile
    Allele (33)
    Strain: WBStrain00055467
    RNASeq_FPKM (74)
    GO_annotation: 00013889
      00013890
      00013891
      00013892
      00013893
      00013894
      00013895
      00105739
      00109967
    Ortholog: WBGene00026516 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00161381 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00162423 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00077035 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00134596 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00193453 Caenorhabditis brenneri From_analysis: WormBase-Compara
      WBGene00225110 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g12299 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g6829 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g3643 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g7738 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g13477 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g25315 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP31.g575 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g8050 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g18630 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g10347 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g7686 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g622 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00869.g14650 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-ile-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g14681 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00194.g6746 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_11623 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_000547 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g05972 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g631 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_10067700 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g1856 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00206630 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00216559 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00237052 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00258749 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00287808 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000001846 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Panther
      SGD:S000004070 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Panther
      FB:FBgn0035909 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-060201-4 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:6631 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:6632 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
      MGI:1917611 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:2667537 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
      RGD:71020 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1310538 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
    Paralog: WBGene00002071 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: ile-1 is orthologous to the human gene human ERGIC-53, which when mutated leads to deficiency of coagulation factors V/VIII (OMIM:227300). Paper_evidence: WBPaper00004103
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable mannose binding activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in factor V deficiency and factor XIII deficiency. Is an ortholog of human LMAN1 (lectin, mannose binding 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:2211 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6631)
      DOID:2216 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6631)
  Molecular_info: Corresponding_CDS: K07A1.8
    Corresponding_transcript: K07A1.8.1
    Other_sequence (64)
    Associated_feature: WBsf649498
      WBsf664767
      WBsf976906
      WBsf976907
      WBsf976908
      WBsf976909
      WBsf984761
      WBsf220109
      WBsf220110
      WBsf220111
  Experimental_info: RNAi_result: WBRNAi00076548 Inferred_automatically: RNAi_primary
      WBRNAi00003946 Inferred_automatically: RNAi_primary
      WBRNAi00116834 Inferred_automatically: RNAi_primary
      WBRNAi00050093 Inferred_automatically: RNAi_primary
      WBRNAi00034034 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1018481
      Expr1031223
      Expr1153795
      Expr2012718
      Expr2030954
    Drives_construct: WBCnstr00036477
    Construct_product: WBCnstr00036477
    Microarray_results (23)
    Expression_cluster (138)
    Interaction: WBInteraction000038620
      WBInteraction000049182
      WBInteraction000109096
      WBInteraction000113731
      WBInteraction000144675
      WBInteraction000147651
      WBInteraction000151310
      WBInteraction000161670
      WBInteraction000171006
      WBInteraction000178042
      WBInteraction000183368
      WBInteraction000195596
      WBInteraction000195900
      WBInteraction000202319
      WBInteraction000212194
      WBInteraction000213653
      WBInteraction000218675
      WBInteraction000226567
      WBInteraction000227689
      WBInteraction000228974
      WBInteraction000229199
      WBInteraction000232328
      WBInteraction000241725
      WBInteraction000244608
      WBInteraction000258942
      WBInteraction000270767
      WBInteraction000281640
      WBInteraction000285759
      WBInteraction000286966
      WBInteraction000287556
      WBInteraction000294361
      WBInteraction000295581
      WBInteraction000310134
      WBInteraction000313662
      WBInteraction000315844
      WBInteraction000317103
      WBInteraction000319624
      WBInteraction000331160
      WBInteraction000333518
      WBInteraction000336572
      WBInteraction000339101
      WBInteraction000347371
      WBInteraction000348570
      WBInteraction000353712
      WBInteraction000355429
      WBInteraction000358890
      WBInteraction000362135
      WBInteraction000367260
      WBInteraction000376568
      WBInteraction000385905
      WBInteraction000386084
      WBInteraction000386352
      WBInteraction000394966
      WBInteraction000400293
      WBInteraction000404601
      WBInteraction000405484
      WBInteraction000429559
      WBInteraction000430694
      WBInteraction000432552
      WBInteraction000439680
      WBInteraction000448275
      WBInteraction000539551
      WBInteraction000557852
      WBInteraction000559365
      WBInteraction000563118
      WBInteraction000563967
      WBInteraction000571887
      WBInteraction000573447
      WBInteraction000579046
      WBInteraction000579060
      WBInteraction000579238
      WBInteraction000579402
      WBInteraction000582787
      WBInteraction000583015
      WBInteraction000586010
  Map_info: Map: I Position: 3.8072 Error: 0.000397
    Positive: Positive_clone: K07A1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00064057
    WBPaper00064339
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene