WormBase Tree Display for Gene: WBGene00001808

WBGene00001808 Evidence: Person_evidence: WBPerson1846
  SMap: S_parent: Sequence: T10G3
  Identity: Version: 1
    Name: CGC_name: gut-2 Person_evidence: WBPerson579
      Sequence_name: T10G3.6
      Molecular_name: T10G3.6a
        T10G3.6a.1
        CE37990
        T10G3.6b
        CE45330
        T10G3.6b.1
      Other_name: lsm-2 CGC_data_submission
        CELE_T10G3.6 Accession_evidence: NDB BX284605
      Public_name: gut-2
    DB_info: Database: AceView gene 5N979
        WormQTL gene WBGene00001808
        WormFlux gene WBGene00001808
        NDB locus_tag CELE_T10G3.6
        Panther gene CAEEL|WormBase=WBGene00001808|UniProtKB=P92022
          family PTHR13829
        NCBI gene 179833
        RefSeq protein NM_001269582.2
            NM_001269583.3
        TREEFAM TREEFAM_ID TF314960
        TrEMBL UniProtAcc P92022
            E1B6V1
        UniProt_GCRP UniProtAcc P92022
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gut
    Allele (31)
    Legacy_information: [C.elegansII] lw6 : E cells fail to gastrulate, division rate does not slow; mutant EMS not responsive to WT P2 induction. lw6/Df similar. OA>10: it92, lw63 (Gro, sterile). Cloned: cosmid rescue (T10G8). [EH; CB]
      [Shaw JE] lw6 and it92 are not null alleles. lw6 and it92 are recessive, strict maternal effect lethal. Dead embryos arrest development with approximately normal cell number but no morphogenesis. Dead embryos are highly penetrant for lack of both differentiated gut cells and pharyngeal muscle. Other tissues (hypodermal, neuronal, body-wall muscle) are present. Early defects in E lineage,i.e. early 2E to 4E division and failure to gastrulate, highly penetrant. Null phenotype likely recessive slow-growing, sterile adult.
    Strain: WBStrain00036163
      WBStrain00036228
    RNASeq_FPKM (74)
    GO_annotation (19)
    Ortholog: WBGene00052810 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00178269 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00219508 Caenorhabditis brenneri From_analysis: WormBase-Compara
      WBGene00225169 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g752 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g11031 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g19820 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g3074 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g19093 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g12092 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g8261 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g1971 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g9165 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g7743 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cni-gut-2 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold282.g735 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      FL83_03811 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_018587 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g04456 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g23206 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_50160300 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrV_pilon.g16259 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00239021 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00112087 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00264816 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00290231 Trichuris muris From_analysis: WormBase-Compara
      WBGene00301162 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000000122 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0036277 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-000616-10 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:13940 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:90676 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1598536 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
    Structured_description: Concise_description: gut-2 encodes a member of the Sm protein family with highest similarity to human U6 snRNA-associated Sm-like protein, LSm2, that affects embryonic viability. Paper_evidence: WBPaper00012624
            WBPaper00023072
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to contribute to RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in P-body. Predicted to be part of Lsm1-7-Pat1 complex and ribonucleoprotein complex. Is an ortholog of human LSM2 (LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T10G3.6a
      T10G3.6b
    Corresponding_CDS_history: T10G3.6:wp138
    Corresponding_transcript: T10G3.6a.1
      T10G3.6b.1
    Other_sequence (54)
    Associated_feature: WBsf647462
      WBsf662028
      WBsf232784
  Experimental_info: RNAi_result (28)
    Expr_pattern: Expr1016964
      Expr1031059
      Expr1156677
      Expr2012349
      Expr2030585
    Microarray_results (20)
    Expression_cluster (131)
    Interaction: WBInteraction000008467
      WBInteraction000008468
      WBInteraction000008469
      WBInteraction000008470
      WBInteraction000032737
      WBInteraction000034529
      WBInteraction000034685
      WBInteraction000034906
      WBInteraction000035140
      WBInteraction000035261
      WBInteraction000035267
      WBInteraction000035315
      WBInteraction000035511
      WBInteraction000035630
      WBInteraction000035966
      WBInteraction000036256
      WBInteraction000036411
      WBInteraction000036412
      WBInteraction000036500
      WBInteraction000036501
      WBInteraction000036548
      WBInteraction000036927
      WBInteraction000037054
      WBInteraction000037679
      WBInteraction000038147
      WBInteraction000038148
      WBInteraction000038149
      WBInteraction000038150
      WBInteraction000038188
      WBInteraction000039095
      WBInteraction000039568
      WBInteraction000039670
      WBInteraction000039671
      WBInteraction000039672
      WBInteraction000040120
      WBInteraction000040485
      WBInteraction000041479
      WBInteraction000041480
      WBInteraction000041481
      WBInteraction000041712
      WBInteraction000042039
      WBInteraction000042040
      WBInteraction000042695
      WBInteraction000043227
      WBInteraction000043228
      WBInteraction000043251
      WBInteraction000043696
      WBInteraction000043760
      WBInteraction000044940
      WBInteraction000044957
      WBInteraction000044958
      WBInteraction000044959
      WBInteraction000044960
      WBInteraction000044961
      WBInteraction000044962
      WBInteraction000044963
      WBInteraction000045543
      WBInteraction000045700
      WBInteraction000045701
      WBInteraction000046598
      WBInteraction000046599
      WBInteraction000046600
      WBInteraction000046601
      WBInteraction000046602
      WBInteraction000047214
      WBInteraction000048408
      WBInteraction000049746
      WBInteraction000050108
      WBInteraction000050518
      WBInteraction000050561
      WBInteraction000051874
      WBInteraction000051907
      WBInteraction000101436
      WBInteraction000101462
      WBInteraction000101480
      WBInteraction000101541
      WBInteraction000101817
      WBInteraction000101970
      WBInteraction000102652
      WBInteraction000103431
      WBInteraction000103433
      WBInteraction000103751
      WBInteraction000105241
      WBInteraction000106468
      WBInteraction000106778
      WBInteraction000106790
      WBInteraction000108931
      WBInteraction000108932
      WBInteraction000108933
      WBInteraction000108937
      WBInteraction000110358
      WBInteraction000110424
      WBInteraction000111404
      WBInteraction000111801
      WBInteraction000111944
      WBInteraction000111991
      WBInteraction000112058
      WBInteraction000119716
      WBInteraction000119717
      WBInteraction000120145
      WBInteraction000120414
      WBInteraction000120522
      WBInteraction000120671
      WBInteraction000120786
      WBInteraction000121035
      WBInteraction000121089
      WBInteraction000123995
      WBInteraction000124077
      WBInteraction000124078
      WBInteraction000127519
      WBInteraction000127620
      WBInteraction000127774
      WBInteraction000127850
      WBInteraction000127896
      WBInteraction000128258
      WBInteraction000128259
      WBInteraction000128260
      WBInteraction000128261
      WBInteraction000128262
      WBInteraction000128263
      WBInteraction000128264
      WBInteraction000128265
      WBInteraction000128266
      WBInteraction000128267
      WBInteraction000128268
      WBInteraction000128269
      WBInteraction000128270
      WBInteraction000128271
      WBInteraction000128272
      WBInteraction000128273
      WBInteraction000128274
      WBInteraction000128275
      WBInteraction000128276
      WBInteraction000128277
      WBInteraction000128282
      WBInteraction000128374
      WBInteraction000128407
      WBInteraction000128533
      WBInteraction000128597
      WBInteraction000128657
      WBInteraction000128784
      WBInteraction000128858
      WBInteraction000128882
      WBInteraction000128907
      WBInteraction000128938
      WBInteraction000128966
      WBInteraction000130152
      WBInteraction000130188
      WBInteraction000130234
      WBInteraction000130646
      WBInteraction000130707
      WBInteraction000130863
      WBInteraction000131029
      WBInteraction000131133
      WBInteraction000131224
      WBInteraction000131317
      WBInteraction000131374
      WBInteraction000131409
      WBInteraction000131482
      WBInteraction000131832
      WBInteraction000131945
      WBInteraction000132035
      WBInteraction000132102
      WBInteraction000132196
      WBInteraction000132277
      WBInteraction000132325
      WBInteraction000132404
      WBInteraction000132454
      WBInteraction000132533
      WBInteraction000132672
      WBInteraction000132795
      WBInteraction000132846
      WBInteraction000133578
      WBInteraction000133745
      WBInteraction000134218
      WBInteraction000134219
      WBInteraction000136380
      WBInteraction000138205
      WBInteraction000138206
      WBInteraction000138828
      WBInteraction000139157
      WBInteraction000141554
      WBInteraction000142685
      WBInteraction000142686
      WBInteraction000142720
      WBInteraction000146976
      WBInteraction000152930
      WBInteraction000157611
      WBInteraction000161388
      WBInteraction000162988
      WBInteraction000172106
      WBInteraction000182351
      WBInteraction000190347
      WBInteraction000190640
      WBInteraction000191680
      WBInteraction000199948
      WBInteraction000203510
      WBInteraction000205965
      WBInteraction000206325
      WBInteraction000209406
      WBInteraction000216969
      WBInteraction000223792
      WBInteraction000223793
      WBInteraction000229459
      WBInteraction000233066
      WBInteraction000238627
      WBInteraction000241796
      WBInteraction000241797
      WBInteraction000243321
      WBInteraction000243401
      WBInteraction000243456
      WBInteraction000247240
      WBInteraction000281022
      WBInteraction000290499
      WBInteraction000291575
      WBInteraction000299476
      WBInteraction000299740
      WBInteraction000334206
      WBInteraction000340015
      WBInteraction000342927
      WBInteraction000342928
      WBInteraction000346271
      WBInteraction000352018
      WBInteraction000352019
      WBInteraction000352020
      WBInteraction000353218
      WBInteraction000355574
      WBInteraction000355575
      WBInteraction000359183
      WBInteraction000359184
      WBInteraction000361597
      WBInteraction000362751
      WBInteraction000363067
      WBInteraction000363068
      WBInteraction000365535
      WBInteraction000365536
      WBInteraction000373616
      WBInteraction000376095
      WBInteraction000378200
      WBInteraction000383490
      WBInteraction000383491
      WBInteraction000386863
      WBInteraction000386864
      WBInteraction000386865
      WBInteraction000390174
      WBInteraction000390175
      WBInteraction000394305
      WBInteraction000394306
      WBInteraction000398670
      WBInteraction000398671
      WBInteraction000401415
      WBInteraction000402950
      WBInteraction000408903
      WBInteraction000410361
      WBInteraction000410362
      WBInteraction000410363
      WBInteraction000413418
      WBInteraction000413419
      WBInteraction000413420
      WBInteraction000414970
      WBInteraction000414971
      WBInteraction000415335
      WBInteraction000418165
      WBInteraction000418166
      WBInteraction000421323
      WBInteraction000421324
      WBInteraction000422876
      WBInteraction000426137
      WBInteraction000431007
      WBInteraction000431008
      WBInteraction000435967
      WBInteraction000446877
      WBInteraction000448008
      WBInteraction000448009
      WBInteraction000449739
      WBInteraction000449740
      WBInteraction000449741
      WBInteraction000453319
      WBInteraction000453320
      WBInteraction000453321
      WBInteraction000454830
      WBInteraction000455195
      WBInteraction000455684
      WBInteraction000462497
      WBInteraction000462498
      WBInteraction000462903
      WBInteraction000464011
      WBInteraction000464012
      WBInteraction000464409
      WBInteraction000464410
      WBInteraction000464411
      WBInteraction000464412
      WBInteraction000464413
      WBInteraction000464734
      WBInteraction000465286
      WBInteraction000466055
      WBInteraction000466503
      WBInteraction000466504
      WBInteraction000466793
      WBInteraction000467252
      WBInteraction000467253
      WBInteraction000467254
      WBInteraction000467521
      WBInteraction000467522
      WBInteraction000468676
      WBInteraction000468677
      WBInteraction000468678
      WBInteraction000468913
      WBInteraction000468914
      WBInteraction000469427
      WBInteraction000469428
      WBInteraction000469429
      WBInteraction000469430
      WBInteraction000471191
      WBInteraction000471707
      WBInteraction000472763
      WBInteraction000472764
      WBInteraction000473080
      WBInteraction000473081
      WBInteraction000473737
      WBInteraction000473738
      WBInteraction000473739
      WBInteraction000474111
      WBInteraction000474761
      WBInteraction000475429
      WBInteraction000475430
      WBInteraction000534766
      WBInteraction000542475
      WBInteraction000555541
      WBInteraction000576300
  Map_info: Map: V Position: 5.35258 Error: 0.004597
    Well_ordered
    Positive: Positive_clone: K10B8
        T10G3 Inferred_automatically: From sequence, transcript, pseudogene data
    Negative: Negative_clone: R11G10
    Mapping_data: 2_point: 7109
      Multi_point: 3848
  Reference: WBPaper00012624
    WBPaper00014687
    WBPaper00015015
    WBPaper00021955
    WBPaper00022720
    WBPaper00023072
    WBPaper00038491
    WBPaper00046572
    WBPaper00055090
    WBPaper00059527
  Remark: The gut-2 gene was merged with lsm-2 following advice from the CGC. gut-2 is the main name for this gene. CGC_data_submission
  Method: Gene