Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00018921

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00018921SMapS_parentSequenceF56A6
IdentityVersion3
NameCGC_namesago-2Paper_evidenceWBPaper00028800
Person_evidenceWBPerson419
Sequence_nameF56A6.1
Molecular_nameF56A6.1a
F56A6.1a.1
CE25906
F56A6.1b
CE33401
F56A6.1b.1
Other_namewago-6Paper_evidenceWBPaper00035262
Y65B4A.gCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_F56A6.1Accession_evidenceNDBBX284601
Public_namesago-2
DB_infoDatabaseAceViewgene1B93
WormQTLgeneWBGene00018921
WormFluxgeneWBGene00018921
NDBlocus_tagCELE_F56A6.1
PanthergeneCAEEL|WormBase=WBGene00018921|UniProtKB=A0A0U1RML5
familyPTHR22891
NCBIgene171653
RefSeqproteinNM_001392310.1
NM_058357.4
TREEFAMTREEFAM_IDTF316656
TrEMBLUniProtAccA0A0U1RML5
A0A0U1RML6
UniProt_GCRPUniProtAccA0A0U1RML5
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:01WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
211 Dec 2006 12:13:29WBPerson1847Name_changeCGC_namesago-2
326 Mar 2014 10:22:27WBPerson2970Name_changeOther_namewago-6
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsago
Allele (26)
Possibly_affected_byWBVar02158862
StrainWBStrain00040439
WBStrain00040440
WBStrain00040441
WBStrain00040446
WBStrain00054819
WBStrain00054832
In_clusterconserved_RDE-1_cluster
conserved_miRNA_siRNA_cluster
RNASeq_FPKM (74)
GO_annotation00001863
00001864
00123898
00123899
Ortholog (46)
Paralog (22)
Structured_descriptionConcise_descriptionsago-2 encodes an Argonaute homolog that is partially required for theamplification phase of RNAi responses; a multiply mutant strain (MAGO),consisting of ppw-1(tm914), sago-1(tm1195), sago-2(tm894),F58G1.1(tm1019), C06A1.4(tm887), and M03D4.6(tm1144) alleles, iscompletely resistant to both germline and somatic RNAi; sago-2 isgenetically redundant with ppw-1 and sago-1, with any one of these genesbeing able to transgenically partially restore the deficiency of MAGOworms; GFP-tagged SAGO-2 binds small secondary siRNAs produced by RNAiagainst GFP; SAGO-2 overexpression does not rescue RNAi defects in rrf-1mutants, and MAGO is not transgenically rescued by rde-1.Paper_evidenceWBPaper00028800
Curator_confirmedWBPerson567
Date_last_updated06 Jan 2007 00:00:00
Automated_descriptionPredicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Expressed in male.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF56A6.1a
F56A6.1b
Corresponding_transcriptF56A6.1a.1
F56A6.1b.1
Other_sequenceCJC01979_1
CR03009
CBC12181_1
CRC07614_1
CJC12846_1
Associated_featureWBsf643023
WBsf217148
WBsf217149
WBsf217150
Experimental_infoRNAi_result (8)
Expr_patternExpr16414
Expr1038163
Expr1152383
Expr2015582
Expr2033817
Microarray_results (44)
Expression_cluster (189)
Interaction (60)
Map_infoMapIPosition-18.7723Error0.068223
PositivePositive_cloneF56A6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (12)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene