kin-3 encodes an ortholog of the catalytic subunit of casein kinase II alpha, which in Drosophila and mammals is required for normal circadian rhythms, and which directly phosphorylates the Drosophila PERIOD protein (which itself regulates circadian rhythms); by analogy, KIN-3 might be expected to help regulate heterochronic functions dependent on such proteins as LIN-42.
Enables protein serine/threonine kinase activity. Involved in response to hermaphrodite contact and vulval location. Located in neuronal cell body; nucleus; and plasma membrane bounded cell projection. Part of protein kinase CK2 complex. Expressed in oocyte. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human CSNK2A1 (casein kinase 2 alpha 1) and CSNK2A3 (casein kinase 2 alpha 3).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.