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WormBase Tree Display for Gene: WBGene00006946

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Name Class

WBGene00006946SMapS_parentSequenceC34E10
IdentityVersion3
NameCGC_nameprx-10Paper_evidenceWBPaper00035972
Person_evidenceWBPerson2754
Sequence_nameC34E10.4
Molecular_name (12)
Other_namewrs-2
wars-2Person_evidenceWBPerson36
WBPerson10953
CELE_C34E10.4Accession_evidenceNDBBX284603
Public_nameprx-10
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:43WBPerson1971EventImportedInitial conversion from geneace
229 Jan 2010 14:16:16WBPerson2970Name_changeCGC_namewars-2
Other_namewrs-2
326 Jul 2010 11:40:25WBPerson2970Name_changeCGC_nameprx-10
Other_namewars-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classprx
Allele (47)
StrainWBStrain00034119
RNASeq_FPKM (74)
GO_annotation00006595
00006596
00006597
00006598
00006599
00006600
00006601
00006602
00006603
00006604
00006605
00006606
00006607
00006608
00006609
00006610
00006611
00006612
00006613
00006614
00006615
00115098
00115099
00115100
00115101
00115102
00115103
00115104
00115105
00115106
00115107
Contained_in_operonCEOP3268
Ortholog (37)
ParalogWBGene00006945Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionThis is a complicated gene locus that produces two distinct gene products, prx-10 and wars-2/wrs-2; transcription of this locus produces a large primary transcript containing the coding potential for functionally different proteins; the transcript can be processed (by an unknown mechanism) to allow for the translation of either the 5' (PRX-10) gene product or the 3' (WARS-2) gene product; prx-10 encodes a PeRoXisome assembly factor whereas wars-2/wrs-2 encodes a tryptophanyl (W) tRNA synthetase.Curator_confirmedWBPerson1983
Date_last_updated16 Nov 2011 00:00:00
Automated_descriptionPredicted to enable tryptophan-tRNA ligase activity. Predicted to be involved in mitochondrial tryptophanyl-tRNA aminoacylation. Predicted to be located in mitochondrial matrix. Used to study obesity. Is an ortholog of human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:9970Homo sapiensPaper_evidenceWBPaper00035972
Curator_confirmedWBPerson38202
Date_last_updated29 Jun 2018 00:00:00
Potential_modelEFO:MONDO:0013150Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12730)
Models_disease_assertedWBDOannot00000573
Molecular_infoCorresponding_CDSC34E10.4a
C34E10.4b
Corresponding_CDS_historyC34E10.4:wp134
Corresponding_transcript (8)
Other_sequence (32)
Associated_featureWBsf645156
WBsf224891
Experimental_infoRNAi_result (11)
Expr_patternExpr1016304
Expr1032960
Expr1145901
Expr2015118
Expr2033356
Drives_constructWBCnstr00037879
Construct_productWBCnstr00037879
Microarray_results (25)
Expression_cluster (85)
InteractionWBInteraction000043588
WBInteraction000213225
WBInteraction000274248
WBInteraction000289232
WBInteraction000310475
WBInteraction000315221
WBInteraction000379995
WBInteraction000396224
WBInteraction000442642
WBInteraction000567677
Map_infoMapIIIPosition-1.86188Error0.001995
PositivePositive_cloneC34E10Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00005877
WBPaper00027315
WBPaper00035972
WBPaper00038491
WBPaper00049625
WBPaper00055090
WBPaper00059323
WBPaper00062224
Remarkdl1 : probably mitochondrial
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene