WormBase Tree Display for Gene: WBGene00002064

WBGene00002064 SMap: S_parent: Sequence: T05G5
  Identity: Version: 1
    Name: CGC_name: iff-1 Person_evidence: WBPerson284
      Sequence_name: T05G5.10
      Molecular_name: T05G5.10a
        T05G5.10a.1
        CE37787
        T05G5.10b
        CE00503
        T05G5.10c
        CE46328
        T05G5.10b.1
        T05G5.10c.1
      Other_name: CELE_T05G5.10 Accession_evidence: NDB BX284603
      Public_name: iff-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:26 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: iff
    Allele (19)
    Strain: WBStrain00022686
      WBStrain00022688
    RNASeq_FPKM (74)
    GO_annotation: 00008864
      00008865
      00008866
      00008867
      00008868
      00008869
      00008870
      00008871
      00008872
      00008873
      00008874
      00008875
      00043233
      00043234
      00043235
      00043236
      00043237
      00043238
      00043239
      00109954
      00109955
      00109956
      00109957
      00109958
    Ortholog: WBGene00055037 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00031496 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00141291 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00103813 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00125787 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00234297 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g6921 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g3974 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g8170 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g9693 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g16883 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g20218 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g11993 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP39.g79 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g3431 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_14060.g24502 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_III.g10745 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp5_scaffold_00842.g15990 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_23729 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_009500 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g08107 Oscheius tipulae From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g13814 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g14846 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_30199310 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g8690 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00248246 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00263080 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00296906 Trichuris muris From_analysis: WormBase-Compara
      WBGene00299875 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000003808 Saccharomyces cerevisiae From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      SGD:S000000760 Saccharomyces cerevisiae From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0285952 Drosophila melanogaster From_analysis: Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-040426-2229 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-040426-2405 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:3300 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1933735 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:106248 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1308029 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog: WBGene00002065 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: iff-1 encodes an eIF-5A homolog that affects fertility and is required for germ cell proliferation and for some P granule components to localize properly; expression is germline specific and mRNA is expressed in the distal region of gonads where germ cells actively proliferate. Paper_evidence: WBPaper00012310
            WBPaper00018717
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable translation elongation factor activity. Involved in gamete generation and protein localization. Predicted to be located in cytoplasm. Expressed in germ line and gonad. Human ortholog(s) of this gene implicated in colorectal cancer. Is an ortholog of human EIF5A (eukaryotic translation initiation factor 5A). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9256 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3300)
  Molecular_info: Corresponding_CDS: T05G5.10a
      T05G5.10b
      T05G5.10c
    Corresponding_CDS_history: T05G5.10:wp135
    Corresponding_transcript: T05G5.10a.1
      T05G5.10b.1
      T05G5.10c.1
    Other_sequence (107)
    Associated_feature: WBsf651400
      WBsf667319
      WBsf667320
      WBsf993786
      WBsf1015666
  Experimental_info: RNAi_result (15)
    Expr_pattern: Expr2909
      Expr2911
      Expr2912
      Expr1021225
      Expr1031217
      Expr1156177
      Expr2012691
      Expr2030927
    Drives_construct: WBCnstr00036483
    Construct_product: WBCnstr00036483
    Regulate_expr_cluster: WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_upregulated_protein
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
    Antibody: WBAntibody00000726
    Microarray_results (23)
    Expression_cluster (235)
    Interaction (346)
  Map_info: Map: III Position: 0.949142 Error: 0.006732
    Positive: Positive_clone: T05G5 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4195
        4435
    Pseudo_map_position
  Reference (15)
  Remark: Sequence connection from [Iino Y]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene