WormBase Tree Display for Gene: WBGene00020436

WBGene00020436 SMap: S_parent: Sequence: T12A2
  Identity: Version: 2
    Name: CGC_name: amdh-1 Person_evidence: WBPerson42707
            WBPerson917
      Sequence_name: T12A2.1
      Molecular_name: T12A2.1
        T12A2.1.1
        CE44585
      Other_name: CELE_T12A2.1 Accession_evidence: NDB BX284603
      Public_name: amdh-1
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:03 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 19 Apr 2021 01:27:01 WBPerson1983 Name_change: CGC_name: amdh-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: amdh
    Allele (254)
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog (48)
    Structured_description: Automated_description: Predicted to enable imidazolonepropionase activity. Predicted to be involved in histidine catabolic process. Predicted to be located in cytoplasm. Is an ortholog of human AMDHD1 (amidohydrolase domain containing 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T12A2.1
    Corresponding_CDS_history: T12A2.1:wp212
    Corresponding_transcript: T12A2.1.1
    Other_sequence (47)
    Associated_feature: WBsf645257
      WBsf659043
      WBsf992692
      WBsf992693
      WBsf225078
  Experimental_info: RNAi_result (13)
    Expr_pattern: Expr1013414
      Expr1038912
      Expr1156745
      Expr2006116
      Expr2024330
    Regulate_expr_cluster: WBPaper00064232:amdh-1(uth29)_downregulated
      WBPaper00064232:amdh-1(uth29)_upregulated
    Microarray_results (19)
    Expression_cluster: WBPaper00031040:Cluster_5
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032425:down_in_zfp-1
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037682:sma-2_downregulated
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:germline-precursors_embryo_enriched
      WBPaper00037950:germline-precursors_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_embryo_enriched
      WBPaper00037950:hypodermis_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00041075:hcf-1(-)_skn-1(+)_upregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:flat_dev_expression
      WBPaper00046121:ecdoderm_unique
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00049098:heat-induced_N2
      WBPaper00049217:TCER-1_upregulated
      WBPaper00049290:rsks-1(sv31)_upregulated
      WBPaper00049736:15deg-then-25deg(12hr)_upregulated_N2
      WBPaper00050193:dpy-27(RNAi)_downregulated_L1
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_specific
      WBPaper00051558:fog-2(q71)_regulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053814:15C_downregulated_OP50
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00054872:egl-9(sa307)_downregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Psora_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055364:uaf-1(n4588)_downregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056218:daf-16(mu86)_downregulated_Day7
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056826:SGP_biased
      WBPaper00057288:Cold_downregulated_protein
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059117:B.subtilis_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:B_F_K_Kp_U_Y
      WBPaper00061340:hyp7_C_lineage
      WBPaper00061340:Rectal_gland
      WBPaper00061340:T
      WBPaper00061340:Tail_hypodermis
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061405:S.aureus_downregulated_starvation
      WBPaper00061527:F55G1.15_14159-ncx-6
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062590:Aging_downregulated_hypodermis
      WBPaper00062590:Aging_downregulated_neuron
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064232:amdh-1(uth29)_downregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065158:25C_vs_15C_upregulated_WholeAnimal
      WBPaper00065258:anchor-cell_enriched
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:2_0
      WBPaper00065841:30_1
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_3_5
      cgc4489_group_10
      WBPaper00035227:heat_shock_regulated
      WBPaper00035560:ahr-1_downregulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036123:Cadmium_regulated
      WBPaper00036286:Pattern_I
      WBPaper00037695:CC_3-day
      WBPaper00040963:TA200_down
      WBPaper00040963:TA300_down
      WBPaper00041002:HF_11d_0.2mM_Up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_3h
      WBPaper00042234:xpa-1_upregulated
      WBPaper00045015:nhr-25(RNAi)_downregulated
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
    Interaction: WBInteraction000108874
      WBInteraction000111143
      WBInteraction000134313
      WBInteraction000282862
      WBInteraction000464857
  Map_info: Map: III Position: -1.4071
    Positive: Positive_clone: T12A2 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00064232
    WBPaper00065140
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene