WormBase Tree Display for Gene: WBGene00013747

WBGene00013747 SMap: S_parent: Sequence: Y113G7A
  Identity: Version: 2
    Name: CGC_name: spe-19 Person_evidence: WBPerson252
      Sequence_name: Y113G7A.10
      Molecular_name: Y113G7A.10
        Y113G7A.10.1
        CE40399
      Other_name: CELE_Y113G7A.10 Accession_evidence: NDB BX284605
      Public_name: spe-19
    DB_info: Database: AceView gene 5U510
        WormQTL gene WBGene00013747
        WormFlux gene WBGene00013747
        NDB locus_tag CELE_Y113G7A.10
        NCBI gene 190958
        RefSeq protein NM_075470.5
        TrEMBL UniProtAcc Q9U2Y6
        UniProt_GCRP UniProtAcc Q9U2Y6
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:55 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 20 Jul 2005 12:21:08 WBPerson2970 Name_change: CGC_name: spe-19
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: spe
    Allele (198)
    Strain: WBStrain00037605
      WBStrain00000052
    RNASeq_FPKM (74)
    GO_annotation (2)
    Ortholog (17)
    Structured_description: Concise_description: spe-19 is predicted to encode a novel single-pass transmembrane protein with no significant similarity to any other gene product; spe-19 is required for hermaphrodite spermiogenesis or sperm activation but not for male-derived sperm activation (sperm activation is the morphogenesis of a round non-motile spermatid to an amoeboid crawling sperm); however, spe-19 mutant hermaphrodite spermatids can transactivate to form functional sperm during mating with males; spe-19 is likely to be the receptor/co-receptor for the sperm activation signal; genetic and phenotypic evidence suggests that spe-19 acts in a common pathway with spe-8, spe-12, spe-27 and spe-29. Paper_evidence: WBPaper00025244
          Curator_confirmed: WBPerson324
          Date_last_updated: 26 Jul 2010 00:00:00
      Automated_description: Involved in spermatid development. Predicted to be located in membrane. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y113G7A.10
    Corresponding_CDS_history: Y113G7A.10:wp101
    Corresponding_transcript: Y113G7A.10.1
    Other_sequence: FG647849.1
    Associated_feature: WBsf1003417
  Experimental_info: RNAi_result: WBRNAi00055377 Inferred_automatically: RNAi_primary
      WBRNAi00036575 Inferred_automatically: RNAi_primary
      WBRNAi00019886 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1011349
      Expr1158893
      Expr2016035
      Expr2034269
    Construct_product: WBCnstr00022514
    Microarray_results (18)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00040209:B.thuringiensis_upregulated_N2
      WBPaper00042194:nhr-114(RNAi)_upregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00044037:eat-2_regulated_nhr-62_dependent
      WBPaper00044037:eat-2_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_upregulated
      WBPaper00044736:rising_dev_expression
      WBPaper00045521:Spermatogenic
      WBPaper00045809:rsd-2(yp10)_downregulated
      WBPaper00046805:csr-1(RNAi)_upregulated_Set1
      WBPaper00046805:csr-1(RNAi)_upregulated_Set2
      WBPaper00046805:P-granule-RNAi_upregulated_Set1
      WBPaper00049498:npr-1(ur89)_regulated_1
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00051404:alg-2(ok304)_downregulated
      WBPaper00053318:Aging_downregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_downregulated_mRNA
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00055013:hmg-3(bar24)_downregulated
      WBPaper00055226:adr-1(tm668)_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055648:sperm_expressed
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056284:ints-9(RNAi)_upregulated
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059754:E.faecalis_OG1RF_upregulated
      WBPaper00060014:set-2(zr2012)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061424:Diet_MYb131_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:Y40H4A.2-ZK1053.2
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062456:doxycycline_upregulated_CB4856_transcript
      WBPaper00062456:doxycycline_upregulated_N2_transcript
      WBPaper00062520:qui-1(db104)_upregulated
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
      WBPaper00062672:let-418(n3536)_upregulated
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064637:cox-5B(RNAi)_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day1_20C
      WBPaper00065096:npr-8(ok1439)_upregulated_Day10_20C
      WBPaper00065096:npr-8(ok1439)_upregulated_Day10_25C
      WBPaper00065841:13_1
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00066038:mip-1(how5)_upregulated
      WBPaper00066110:Cisplatin_upregulated_diploid
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      cgc4386_cluster_6_5
      cgc4489_group_14
      WBPaper00036286:Pattern_E
      WBPaper00040963:TA300_up
      WBPaper00041267:SpaceFlight_Upregulated
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045263:isp-1(qm150)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045263:ProLongevity-mtROS_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      [cgc6390]:mixed_spermatogenesis-somatic
    Interaction (153)
  Map_info: Map: V Position: 24.4739 Error: 0.009415
    Positive: Positive_clone: Y113G7A Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5371
        4745
    Pseudo_map_position
  Reference (21)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene