WormBase Tree Display for Gene: WBGene00003335
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WBGene00003335 | Evidence | Paper_evidence | WBPaper00005825 | ||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F56A12 | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001265 | |||||
Gene_class | mir | ||||||
Allele (11) | |||||||
Strain | WBStrain00027442 | ||||||
WBStrain00027449 | |||||||
WBStrain00027441 | |||||||
WBStrain00040223 | |||||||
WBStrain00040225 | |||||||
WBStrain00040228 | |||||||
WBStrain00051617 | |||||||
In_cluster | LET-7 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00106260 | ||||||
00106261 | |||||||
Structured_description | Concise_description | mir-241 encodes a microRNA, a small non-protein coding RNA and appears to have a potential ortholog in C. briggsae; based on RNA sequence identity, miR-241 belongs to the let-7 family of microRNAs along with C. elegans miR-48 and miR-84 and human let-7, miR-196-1 and miR-196-2; mir-241 acts redundantly with miR-48 and mir-84 to control L2 to L3 larval and larval to adult stage transitions; miR-241 is strongly expressed from the L3 larval stage into the adult stage in normal worms and in glp-4(bn2) mutant worms. | Paper_evidence | WBPaper00005825 | |||
WBPaper00010853 | |||||||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 08 Feb 2005 00:00:00 | ||||||
Automated_description | Involved in miRNA-mediated gene silencing by inhibition of translation and positive regulation of development, heterochronic. Expressed in body wall musculature; excretory canal; hermaphrodite distal tip cell; and touch receptor neurons. Used to study Parkinson's disease. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Experimental_model | DOID:14330 | Homo sapiens | Paper_evidence | WBPaper00035654 | ||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 06 Jan 2014 00:00:00 | ||||||
Disease_relevance | mir-241 is a small non-protein coding RNA that belongs to the let-7 family; microRNA expression profiling studies indicate that mir-241 is overexpressed in an elegans Parkinson''s disease model, the pdr-1 mutant (pdr-1 is orthologous to human PARKIN). | Homo sapiens | Paper_evidence | WBPaper00035654 | |||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 06 Jan 2014 00:00:00 | ||||||
Models_disease_in_annotation | WBDOannot00000268 | ||||||
Molecular_info | Corresponding_transcript | F56A12.4 | |||||
F56A12.4a | |||||||
F56A12.4b | |||||||
Associated_feature | WBsf034325 | ||||||
WBsf979128 | |||||||
WBsf1001991 | |||||||
WBsf1001992 | |||||||
WBsf1001993 | |||||||
WBsf1001994 | |||||||
WBsf1020828 | |||||||
WBsf1020829 | |||||||
WBsf1020830 | |||||||
WBsf1020831 | |||||||
Experimental_info | Expr_pattern | Expr2525 | |||||
Expr3740 | |||||||
Expr3770 | |||||||
Expr3771 | |||||||
Expr8400 | |||||||
Expr8424 | |||||||
Expr10881 | |||||||
Expr12018 | |||||||
Expr12024 | |||||||
Expr12555 | |||||||
Expr13379 | |||||||
Drives_construct | WBCnstr00005522 | ||||||
WBCnstr00011651 | |||||||
WBCnstr00015774 | |||||||
WBCnstr00015775 | |||||||
WBCnstr00017833 | |||||||
Construct_product | WBCnstr00015775 | ||||||
Expression_cluster (38) | |||||||
Interaction (17) | |||||||
WBProcess | WBbiopr:00000083 | ||||||
Map_info | Map | V | Position | 6.27847 | Error | 0.001234 | |
Positive | Inside_rearr | nDf51 | |||||
Positive_clone | F56A12 | Inferred_automatically | From CDS info | ||||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 5653 | |||||
Pos_neg_data | 10750 | ||||||
Pseudo_map_position | |||||||
Reference (52) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |